GI tract Flashcards
When does GI tract development occur
3rd to 12th weeks embryonic age (5 to 14 weeks LMP)
What occurs during GI tract development
Primary germ layer formation, gut tube formation, regionalised changes caused by rotation, swelling, elongation
Organs and glands produced by budding from the gut tube
Describe primary germ layer formation
Gastrulation - Third week, embryo implanted into uterine wall, embryo is a flat disc, comprised of epiblast and hypoblast.
Primitive streak forms
What is the mesoderm
Surrounding muscle, connective tissue and mesenteries
What is the endoderm
EPithelium of the gut tube
What is ectoderm
Innervation of the gut
What does hypoblast give rise to
Extra-embryonic tissue
Describe initial gut folding and tube formation
Gut tube is formed by folding of sheets of cells in two directions
Folding towards the midline along the cranial-caudal axis
Folding towards yolk sac at the cranial and caudal ends
What are hox gene expression boundaries
Specify position of GI tract structures