GI Secretory Meds Flashcards
What is the primary therapeutic action of cimetidine?
Selectively block H2 receptors
H2 antagonists reduce gastric acid secretion by blocking H2 receptors
Which condition is an indication for taking antacids?
Conditions causing hyperacidity
Includes peptic ulcer, gastritis, and hiatal hernia
What common adverse effect should be monitored in a patient taking omeprazole?
Dizziness and headache
CNS effects are common with Proton Pump Inhibitors
Misoprostol is primarily used to prevent which condition?
NSAID-induced gastric ulcers
Typically prescribed for patients at high risk for ulcer development
When administering sucralfate, when should it be given?
On an empty stomach
Food can interfere with its ability to adhere to ulcer sites
Which drug classification neutralizes stomach acid through a chemical reaction?
Antacids
Antacids work by neutralizing stomach acid directly
Patients with renal impairment should exercise caution when taking which medication due to possible electrolyte imbalance?
Antacids
Potential electrolyte imbalances can occur
What is the pregnancy category of misoprostol?
Category X
Associated with risks such as miscarriage and excessive bleeding
How should H2 antagonists be taken?
With or before meals or at bedtime
This timing helps with absorption and effectiveness
What is a potential drug-drug interaction with Proton Pump Inhibitors?
Benzodiazepines or phenytoin (antiseizure meds)
Can lead to toxicity or decreased effectiveness
How does sucralfate work?
Forming an ulcer-adherent complex
Protects ulcer sites from acid, pepsin, and bile salts
When should pancreatic enzymes be administered?
With meals and snacks
Aids in digestion when taken with food
What is a key side effect of misoprostol in women?
Menstrual irregularities
Can also include miscarriages and excessive bleeding
Proton Pump Inhibitors should NOT be:
Opened, chewed, or crushed
This can affect the drug’s effectiveness
What should be monitored in a patient on carbonates?
Electrolyte imbalances
Important to check renal function and electrolyte levels
What CNS effects can H2 antagonists cause?
CNS effects
Dizziness, headache, and confusion
Misoprostol is relatively contraindicated in which group?
Pregnant women
Significant risks associated with pregnancy
How should saliva substitutes be administered?
Swish and NOT swallow
Ensures proper use for dry mouth relief
Sucralfate should be administered when?
On an empty stomach
To ensure it effectively adheres to ulcer sites
What is a potential adverse effect of pancreatic enzymes?
Nausea, abdominal cramps, and diarrhea
Common side effects reported
Proton Pump Inhibitors are indicated for treating which conditions?
Ulcers, GERD, and pathological hypersecretory conditions like Zollinger-Ellison syndrome
What should the nurse assess in a patient on misoprostol?
Pregnancy/lactation and abdominal assessment
Includes monitoring for miscarriage and menstrual disorders
H2 antagonists can affect drug metabolism how?
Slow down metabolism
Can lead to potential toxicity
Antacids can cause what issue?
Rebound acidity
Alkaline stomach makes more acid increasing symptoms and pt takes more antacids
