GI & Respiratory

Question 1

Lactulose

Answer 1

Generlac
MOA: osmotic LAXATIVE decreases intestinal 
used for hepatic encephalopathy
absorption of ammonia
-laxative
-can take 48 hours to take affect

Question 2

Linactolide

Answer 2

Linzess
BOXED WARNING NOT FOR PEDS
MOA: selective Guanalyl Cyclase C agonist on luminal surface
30 min before breakfast on empty stomach
can treat IBS , for weight loss use once a day 30 min b/f meal
SE: diarrhea
swallow whole; can be opened and taken with applesaice

Question 3

Lubiprostone

Answer 3

Amitiza
MOA: CIC 2 chloride channel activator
take 30min before breakfast
for constipation use 24mcg BID
for IBS use 8mcg BID
SE: N/D
CI: bowel obstruction
take with food and water

Question 4

Dexlansoprazole

Answer 4

Dexilant

PPI

Question 5

Esomeprazole

Answer 5

Nexium

PPI

Question 6

Lansoprazole

Answer 6

Prevacid

PPI

Question 7

Pantoprazole

Answer 7

Protonix

PPI

Question 8

Famotidine

Answer 8

Pepcid
H2RA receptor blocker
SE: Confusion
Inc ECG, QT prolong

Question 9

Sucralfate

Answer 9

Carafate

Question 10

Ranitidine

Answer 10

Zantac
h2ra
inc ALT

Question 11

Omeprazole

Answer 11

Prilosec

PPI

Question 12

Dicyclomine

Answer 12

Bentyl
antispasmodic
CI; gi obst.
anticholinergic in >65yo
SE: dry mouth,N/V.blurry vision

Question 13

Hyoscamine

Answer 13

Levsin

Question 14

Promethazine

Answer 14

Phenergan

antihistamine

Question 15

Ondansetron

Answer 15

Zofran

5ht3 antagonist

Question 16

Metoclopramide

Answer 16

Reglan
dopamine antagonist
must take w food
inc mobility and LES tone
BOXED WARNING: tarditive dyskinesia
CI parkinsons GI obstruction
MUST HAVE WITH FOOD
SE Drowsiness

Question 17

Diphenoxylate/Atropine

diphenoxylate inhibits gi motility, atropine discourages abuse

Answer 17

Lomotil
antidiarrheal; d/c if no improvement after 10days
CI; respiratory depression in children
SE; euphoria
liquid for children <13

Question 18

Azelastine

Answer 18

Astepro

histamine antagonist

Question 19

Fluticasone Propionate(nasal)

Answer 19

Flonase

Question 20

Benzonotate

Answer 20

Tessalon Perles

Question 21

Codeine Phosphate with Codeine

Answer 21

Codeine Contin

Question 22

Albuterol

Answer 22

Proair
MDI/DPI
warning CVD,glaucoma,hyperthyroid
SE nervous, tremor, tachycardia, hypoK
shake well b/f use

Question 23

Ipratropium

Answer 23

Atrovent
caution patient with glaucoma, bph
SE dry mouth

Question 24

Albuterol/Ipratropium

Answer 24

Duoneb

Question 25

Tiotropium

Answer 25

Spiriva

LAMA

Question 26

Umeclidinium and Vilanterol

Answer 26

Anoro Ellipta

LAMA/LABA/ICS

Question 27

Montelukast

Answer 27

SIngulair
inhibits leukotrienes
allergic rhinitis and exercise induced bronchoconstriction
BOXED; neuropsychotic events
CI Zariflukast Zileuton
SE: INC LFT URTI

Question 28

Budesonide/formoterol

Answer 28

Symbicort

ICS/LABA

Question 29

Fluticasone/vilanterol

Answer 29

Breo Ellipta

ICS/LABA

Question 30

Fluticasone/salmeterol

Answer 30

Advair

ICS/LABA

Question 31

Hydroxyzine Hydrochloride

Answer 31

Orgatrax

Question 32

Hydroxyzine Pamoate

Answer 32

Vistsril

Question 33

Budesonide

Answer 33

Entocort
3mg for CD
9mg for UC(Uceris)
CI; fungal infection and live vaccines
SE: inc appetite wt gain emotional instability
avoid long term use
assess bone density
avoid grapefruit
first pass; decreased systemic exposure
swallow no crush or chew

Question 34

Fluticasone Propionate

Answer 34

Flovent

Question 35

Umeclidinium

Answer 35

Incruse