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Physio 2 > GI phys-NTs and neuromodulators in the enteric nervous system > Flashcards

GI phys-NTs and neuromodulators in the enteric nervous system Flashcards

1
Q

Acetylcholine (ACh)

A 
Source: Cholinergic neurons
Contraction of smooth muscle in wall of GI organs.
Relaxation of sphincters.
↑ Salivary secretion 
↑ Gastric secretion
↑ Pancreatic secretion
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2
Q

Norepinephrine (NE)

A

Source: Adrenergic neurons
Relaxation of smooth muscle in wall of GI organs.
Contraction of sphincters
↑ Salivary secretion

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3
Q

Vasoactive Intestinal Peptide

A

Source: Neurons of smooth muscle and mucosa.
Relaxation of smooth muscle
↑ Intestinal secretion
↑ Pancreatic secretion

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4
Q

Gastrin-Releasing Peptide (GRP), or Bombesin

A

Source:Neurons of gastric mucosa

↑ Gastrin secretion

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5
Q

Enkephalins (opiates)

A

Source: Neurons of mucosa and smooth muscle.
Contraction of smooth muscle
↓ Intestinal secretion

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6
Q

Neuropeptide Y (NPY)

A

Source: Neurons of mucosa and smooth muscle.
Relaxation of smooth muscle.
↓ Intestinal secretion

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7
Q

Substance P

A

Cosecreted with ACh.
Contraction of smooth muscle
↑ Salivary secretion

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Physio 2 (6 decks)

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