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NUR 326- Patho 1 Exam 3 > GI pharm > Flashcards

GI pharm Flashcards

1
Q

2 ways to treat upper GI disorders/infections

A
  1. inc protective factors
  2. dec aggressive factors
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2
Q

pharm classes of protective factors

A

antacids
sucralfate

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3
Q

pharm classes of aggressive factors

A

H. polyri
H2 blockers
proton pump inhibitors

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4
Q

H. pylori tx

A

several antibiotics + gastric acid inhibitor
combo dec drug resistance

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5
Q

how long is H. pylori tx

A

10-14 days

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6
Q

problems with H. pylori tx

A

dec adherence d/t $$$$

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7
Q

H2 receptor blockers drugs

A

cimetidine, famotidine (2 dines = 20c)

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8
Q

H2 receptors blockers moa

A

blocks H2 in stomach –> dec gastric acid secretion (inc stomach pH)

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9
Q

H2 receptor blockers treat

A

GERD, PUD, heartburn

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10
Q

SE H2 receptors

A

CNS in elderly
inc pneumonia risk

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11
Q

H2 nursing considerations

A

give at least hour apart from antacids
may given prophylaxis (avoid aspiration)
CYP450 inhibitor
*can increase Warfarin effects
give slow in IV push (can cause bradycardia)

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12
Q

Proton pump inhibitor drugs

A

omeprazole, pantoprazole, esomeprazole magnesium

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13
Q

PPI drugs moa

A

blinds and inhibit proton pump (irreversibly inhibits secretion of HCl)

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14
Q

which are more effective: PPI or H2

A

PPI

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15
Q

PPI SE

A

short-term = safe
long-term = inc pneumonia risk, bone loss, stomach cancer

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16
Q

PPI nursing care

A

really only for short-term use

17
Q

sucralfate class

A

mucosal protectant

18
Q

sucralfate moa

A

alters when exposed to gastric acid –> creates thick, sticky (protective barrier)

19
Q

sucralfate treats

A

duodenal + gastric ulcer

20
Q

sucralfate nursing care

A

PO, before meals, dec drug absorption- take after (2h) post other drugs

21
Q

sucralfate SE

A

constipation

22
Q

antacids

A
23
Q

Ondansetron drug class

A

serotonin blocker

24
Q

ondansetron AKA

A

zofran

25
Q

ondansetron moa

A

blocks serotonin receptors in brain and afferent vagal nerves in stomach

NUR 326- Patho 1 Exam 3 (20 decks)

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