GI Pancreatic/Biliary/Intestin Secretions

Question 1

Name the 3 principal enzyme production of the exocrin pancreas?

Answer 1

1. Amylases
2. Lipases
3. Proteases

Question 2

What are the 3 principal proteases?

Answer 2

1. Trypsinogen
2. Chymotrypsinogen
3. Procarboxipeptidase

Question 3

Enzyme in charge of trypsinogen—-> trypsin?

Answer 3

Enterokinase

Question 4

How are chymotrypsinogen and procarboxypeptidase —> into their active forms?

Answer 4

1. Trypsin

Question 5

Principal hormone responsible for the neutralization of gastric acid in the duodenum?

Answer 5

1. Secretin —> ⬆️⬆️HCO3-

Question 6

CCK responds mainly to these substances to ⬆️pancreatic exocrine enzyme secretion ?

Answer 6

1. Fatty acids, amino acids and peptides

Question 7

Secretin acts via the following transporter to ⬆️HCO3- secretion and Cl- reabsorption?

Answer 7

1. CFTR (cystic fibrosis transmembrane regulator)

Question 8

Name 2 of the Primary Bile Acids?

Answer 8

1. Cholic Acid

2. Chenodeoxycholic acid

Question 9

What are Primary Bile Acids conjugated with to become hydrosoluble ?

Primary Bile Acids—-> Primary Bile Salts

Answer 9

1. Glycine

2. Taurine

Question 10

What do Primary Bile Salts form in order to transport liposoluble substances ?

Answer 10

1. Micelles!

Question 11

Where are the micelles (bile salts) actively reabsorbed ?

Answer 11

1. Terminal Ileum!!

Question 12

Main form of cholesterol elimination ?

Answer 12

Micelles

Question 13

Ion transporter responsable maintenance of gradient in enterocytes?

Answer 13

Na-K-Cl Cotransporter

Question 14

Main electrolyte secreted by the intestinal glands (Crypts of Lieberkühn)?

Answer 14

Cl-

Question 15

Cholera toxins main site of action ?

Answer 15

Gs Proteins —> ⬆️cAMP —> ⬆️Cl- —-> ⬆️H2O (secretory diarrhea )