GI Opening Round Flashcards
Case 1
In ischemia, bowel wall may be hyperdense on non-contrast CT
T/F
True
Case 1
What is the best initial study for SBO?
Plain film
Air-fluid levels are typically seen within 48-72 hrs of obstruction
Case 2
What is the best initial study for the diagnosis of appendicitis in children and pregnant women?
Ultrasound
Case 2
Pericolic stranding of the right colon with sparing of the cecal pole is suggestive of what?
Cecal diverticulitis
Case 3
What is the most common type of colonic volvulus?
Sigmoid volvulus (50-75%) is most common
Cecal volvulus is 2nd MC (20-40%)
Case 3
Subtype of cecal volvulus where the cecum flips up and over an adhesion across the ascending colon and presents as an air filled subhepatic structure
Cecal bascule
Case 3
Sign of cecal volvulus on CT
Bird beak sign
Case 3
Purpose of CT in the setting of cecal volvulus
Influence treatment by detecting complications of volvulus
Case 4
What type of diaphragmatic hernia is most associated with GERD?
Sliding-type
Case 4
T/F
1. Bulimia patients are at an increased risk for GERD
- Episodic insomnia is a manifestation of chronic GERD
- True
2. True
Case 4
Four fluoroscopic findings of chronic GERD
Fold Thickening
Granular Appearance
Superficial Ulcerations
Luminal Narrowing
Case 4
Three complications of chronic GERD
Barrett’s Metaplasia
-precursor of AdenoCA
Stricture
Ulceration
Case 5
Which of the following is true regarding colonic diverticulitis?
A. Colonic diverticula are true diverticula
B. Diverticulitis is the MC cause of colovesical fistula
C. Diverticular hemorrhage usu. ensues if diverticulitis is untreated
D. Diverticulitis of the right colon is more likely to progress rapidly to complications
B. Diverticulitis is the MC cause of colovesical fistula
Case 5
What is the role of BE for diverticular disease?
Useful in chronic diverticulosis. Can be helpful for operative planning.
Case 5
What is the finding on BE of acute diverticulitis?
Appearance of an intramural tract
Case 6
What is the MC type of enteric cyst?
Esophageal duplication cyst (25%)
They are most commonly asymptomatic
Case 6
What nucs study can be helpful for the diagnosis of esophageal duplication cysts?
Tc-99m perctechnetate is positive in up to 50% of cases
Case 6
Name three Foregut Congenital Cysts
Neurogenic
Bronchogenic
Enteric duplication
Case 7
What is the MC malignancy of distal small bowel?
Carcinoid
Case 6
Most common symptom of esophageal duplication cyst
- None
Case 7
What is the MC tumor of small bowel?
GIST
Second MC - Lipoma
Case 7 What polyposis syndrome is associated with increased risk of small bowel cancer? A. Lynch syndrome B. Peutz-Jeghers C. Cronkhite-Canada D. Cowden syndrome
B. Peutz-Jeghers
Case 7
What is the MC location for intussusception in adults?
MC etiology?
In Children?
Location - ileoileal
Etiology - polyp / tumor
Location - ileocolonic
Etiology - lymphoid hyperplasia
Case 7
Typical manifestations of small bowel tumors
Bleeding Bowel Obstruction Intussusception (5-15% in adults) - mainly in children 2o to Lymphoid hyperplasia - most are transient SB tumors are typically asymptomatic
Case 8
What is the BE sign at the site of torsion with sigmoid volvulus?
Bird’s beak
Case 8
T/F
1. Volvulus is the 3rd most common cause of colonic obstruction, sigmoid is the most common type of volvulus.
2. Laparotomy and sigmoidopexy are the therapy of choice for sigmoid volvulus
3. A redundant sigmoid colon is a predisposing factor to sigmoid volvulus
4. The development of gangrene is suggested by clinical signs of peritonism or imaging signs of pneumoperitoneum or pneumatosis
- T
- F
- T
- T
Case 9 Which of the following features is most suggestive of a malignant gastric ulcer? A. Gastric antrum location B. Ulcer projects outside gastric lumen C. Clubbed surrounding rugal folds D. Associated duodenal ulcer E. Hampton's line present
C. Clubbed surrounding rugal folds.
B and E are suggestive of benign ulcer
Case 9
Describe clubbing of gastric folds
The termination of a fold swells into a clublike configuration
Case 9 Yes / No Associated with gastric malignancy 1. AIDS 2. Benign gastric ulcer 3. H. Pylori 4. Nitrites and nitrates 5. Partial gastrectomy
- Yes
- No
- Yes
- Yes
- Yes
Case 9
Best imaging study for gastric cancer staging
CT
Case 10
DDx for widening of the presacral space
Rectal perforation - abscess
Sacral chordoma - other sacral bony process (metastasis)
Anorectal carcinoma
Pelvic lipomatosis
Case 9
Define Hampton’s line
- Well-defined thin lucency at the base of the ulcer
- Ulcer collar
- Characteristic of benign ulcer
Case 9
What is clubbing?
- Indicative of malignant gastric ulcer
- The termination of a fold swells into a club-like configuration
Case 10
What is the most common retrorectal tumor
Ependymoma
Case 11
Cause of duodenal obstruction in young female with h/o weight loss that is worsened in supine position compared to upright?
SMA syndrome
Case 11
What is the abnormal SMA angle in SMA syndrome?
Aortomesenteric angle of less than 25 degrees
Case 11
Four predisposing conditions to SMA syndrome
Young women with eating disorders
Burn patients
Patients in body casts
Severe illness and sudden weight loss
Case 11
What is the surgical intervention for SMA syndrome?
Gastrojejunostomy
Case 12
What is the MC type of solid organ injury in blunt trauma?
Splenic injury (25%)
Case 12
What is a potential latent complication in patients who have undergone splenectomy
Encapsulated bacterial sepsis
Case 12
What is a grade 1 splenic injury?
What is a grade 5 splenic injury?
Grade 1: Subcapsular hematoma less than 10% of surface area and /or capsular tear of less than 1 cm, non-expanding and not actively bleeding
Grade 5: Shattered spleen with involvement of vascular pedicle
Case 13
What is the Borchardt triad and what is it diagnostic of?
Pain
Nonproductive retching
Inability to pass NGT
Diagnostic of gastric volvulus
Present 70% of the time
Case 13
What subtype of gastric volvulus results in the antrum being displaced toward the fundus?
Mesenteroaxial volvulus
Case 14
What is the MC histologic subtype of colonic adenomatous polyp
Tubular adenoma (80%) - Very little risk for malignant degeneration
Case 13
What type of gastric volvulus is most common?
Which type is most serious?
What is the typical anatomic defect?
Most common: organoaxial
Most serious: mesenteroaxial (due to increased risk of strangulation)
Abnormal laxity of the gastric ligaments
Case 14
What type of colonic polyp is associated with malignancy?
Villous adenoma
Case 14
What is the malignant potential of a colonic villous adenoma based on size?
1-2 cm
>2 cm
- 10% risk
- 30-40% risk
Case 15 Which of the following is an iatrogenic cause of pneumatosis intestinalis? A. O2 therapy B. Hyperbaric oxygen C. Chemotherapy D. Dialysis
C. Chemotherapy
Also, ischemia, C diff colitis, NEC, steroids, obstruction, trauma, endoscopy, malignancy, Crohn’s dz
Case 15
What is pneumatosis intestinalis cystica?
Benign condition with subserosal blebs in the distal bowel.
Caused by migration of air along bronchovascular pathways to mesentery (Macklin’s pathway)
Case 16
What is the minimal volume for free air to be visible on upright film?
1-2 cc
Case 16
How long does it take for free air to reabsorb following surgery?
Usually 3-10 days.
Case 16
What can affect the reabsorption of pneumoperitoneum?
Body habitus - thin patients taking longer
Postoperative ileus or peritonitis - can prolong
Case 17
What can occur in the duodenum as a result of hyperacidity?
Brunner gland hypertrophy
Case 17
DDx for multiple small filling defects in the duodenal bulb?
Heterotopic Gastric Mucosa
Benign Lymphoid Hyperplasia
Brunners Gland Hyperplasia
Pancreatic Rests
Case 17
Name 4 polyposis syndromes
Familial Adenomatous Polyposis
Peutz-Jeghers Syndrome
Cronkhite-Canada Syndrome
Filiform Polyposis
Case 17
Which polyposis syndrome does not involve the duodenum?
Filiform polyposis
Case 17
Name 4 benign tumors of the duodenum?
What is the MC benign tumor of the duodenum?
Adenoma
Neurofibroma
Leiomyoma (GIST)
Mesenchymal tumors
Mesenchymal tumors
Case 18
Which of these viscera are not related to the descending duodenum?
Aorta, Gallbladder, Common bile duct, Right Kidney, Pancreas
Aorta
Case 18
What adjacent organs bear a close relationship with the duodenum and may result in thickened duodenal folds?
Pancreas
Right Kidney
- Duodenal folds may also be thickened due to spasm from pancreatitis
Case 18
MC cause of duodenal inflammation?
Hyperacidity and peptic ulcer dz
Case 18
Other causes of thickened duodenal folds?
Zollinger-Ellison synd
Eosinophilic Enteritis
Crohn’s disease
Whipple’s disease
Amyloid
Malignancies
Hypoproteinemia
Intramural bleeding
Case 18
What is the MC malignancy of the duodenum?
Adenocarcinoma (64%)
Followed by carcinoid (21%), lymphoma (10%), sarcoma (4%)
Case 19
What is the MC cause of acute pancreatitis in Western society?
Other causes?
Alcohol
- mainly younger patients
- oder patients -> billiary
Trauma Drugs Iatrogenic - ERCP Idiopathic
Case 19
Cullen sign?
Grey Turner sign?
Bluish discoloration around umbilicus
Discoloration along the flanks
Case 19
Nearly all cases of pancreatitis result in some change in which lung base?
Left
- atelectasis
- effusion
- airspace disease
Case 20
What is the MC primary lymphoma of the stomach?
MALT
Mucosa-associated Lymphoid Tissue
Case 20
Name 4 known risk factors for gastrointestinal lymphoma
AIDS
H. Pylori
Celiac Dz
Epstein Bar Virus
Case 20
What is the most common area of the GI tract affected by lymphoma?
Stomach
- half primary and half generalized dz
Lymphoma accounts for only 5% of gastric malignancies
Most are Non-Hodgkins
Primarily affects men and older age groups
Case 21
T or F: Arterial obstruction is the MC cause of ischemic colitis
False
Most commonly caused by low-flow states
- Hypotension
- Heart failure
Case 21
Prognosis of ischemic colitis?
Most patients improve and fully recover
Case 22
What are the MC type of splenic cyst?
Post-traumatic cysts
Congenital epidermoid cysts
Case 22
What is the MC benign neoplasm of the spleen?
Hemangioma
Case 22
What is the MC splenic malignancy?
Lymphoma
Case 23
What are the normal extrinsic impressions of the esophagus on barium swallow?
- Aortic arch
- Left mainstem bronchus
- Left atrium
- Diaphragmatic Hiatus
Case 23
What can produce an anterior esophageal impression on barium swallow?
Pulmonary sling
Case 23
What is dysphagia lusoria?
Impression on the esophagus by any vascular structure
Case 24
What abdominal neoplasms are seen in VHL?
RCC (clear cell) Pheochromocytoma Pancreas - Cystic - Islet cell
Case 24
Describe von Hippel-Lindau dz
AD inheritance
- Capillary angiomatous hamartomas
- CNS involvement of brain and retina
- Typically hemangioblastoma of posterior fossa
- Abd tumors - RCC, pheo, cystic islet cell pancreas
- Mult panc cysts of various sizes
- -> suspect VHL
Case 25
What is the most likely lesion to cause large masses in the gut without obstruction?
Lymphoma
Case 25
What small bowel lesion results in eleveated 5-HIAA in the URINE?
Carcinoid
Case 25
Describe aneurysmal dilation of small bowel
Large mass encasing the small bowel, in which the gut lumen is channeled through the lesion, leaving a false channel surrounded by tumor but without obstruction
- This is a particular characteristic of NH Lymphoma in the SB
Case 26
What is the MC herniated organ in patients with traumatic diaphragmatic rupture?
Stomach
Case 27
What is the MC type of GB polyp?
Cholesterol
Followed by
- Adenoma
- Papilloma
Case 27
Although uncommon, what can metastasize to the gallbladder
Melanoma
Breast CA
Lymphoma
Case 28
What conditions are associated with emphysematous gastritis?
Pulmonary dz
Peptic Ulcer dz
Gastric Outlet Obstruction
Endoscopy (esp w intervention)
Case 28
What is the MC location for intramural gas to occur in the GI tract?
Colon
Case 28
What infectious processes can result in emphysematous gastritis?
Hemolytic Strep
Clostridium species
Coliform bacteria
Case 28
Ingestion of what substances can cause emphysematous gastritis?
Ingestion of corrosive substances
- such as in suicide attempts
Case 29
What is the MC malignancy at the GE junction?
Adenocarcinoma
Case 29
What inflammatory condition predisposes to Adeno CA of the GE junction?
Barrett’s metaplasia
Case 30
What is the Carmen meniscus sign and what does it indicate?
How is CMS best seen?
Large semi-lunar or lenticular shaped hypodense zone
- Seen in ulcerating gastric adenoCAs
- Flattened polypoid mass with a broad central ulceration
- Gastric mucosa adjacent to the polyp forms a smooth inner margin
- Must be located along lesser curvature or antrum to see this sign
Single-contrast or biphasic studies
Case 30
What is the Kirkland (Kirklin’s) complex?
- Seen in ulcerated gastric cancer
- Concave lucent margin around the ulceration
Case 31
Which type of inflammatory bowel disease is associated with higher risk of malignancy?
Ulcerative colitis
Case 31
Is the terminal ileum involved with UC?
Never
Case 31
Which is most likely to cause fistulas - UC vs Crohn’s?
Crohn’s
Case 31
Which IBD has the greatest risk for malignancy?
UC
Case 32
How can you distinguish portal venous gas from pneumobilia?
Portal venous gas is more peripheral
Case 32
What are some benign causes of portal venous gas?
Bowel obstruction
Instrumentation
Bowel surgery
Case 32
In the setting of portal venous gas - what must be excluded?
Catastrophic bowel necrosis
Case 33
How is a malignant gastric stromal tumor distinguished from a benign one on imaging?
Presence of metastasis
- No other imaging characteristics are specific
Case 33
Most common benign submucosal tumor of the stomach?
Stromal tumor (leiomyoma)
Ectopic pancreatic rest is a congenital abnormality that mimics leiomyoma
Case 34 Which of the following is a predisposing factor to the development of cholangiocarcinoma? A. Postviral hepatic fibrosis B. Recurrent bacterial infection C. Echinococcal cyst D. Sclerosing cholangitis
D. Sclerosing cholangitis
Case 34
What is a Klatskin’s tumor
Cholangiocarcinoma that arises from the confluence of the right and left bile ducts
- Typically scirrhous cholangiocarcinoma
- Grows along the ducts
- Can result in a central mass with focal lobar atrophy
Case 35
What is the MC complication of ovarian dermoids?
Torsion
- Malignant degeneration is rare
Case 34
What are the different forms in which cholangiocarcinoma can present?
Biliary Stricture
Biliary Polyp
Liver Mass
Case 35
What sign is pathogmonic of ovarian dermoid?
Fat-fluid level on imaging
Case 35
What variety of tissues are recognized within ovarian dermoids?
Fat
Skin
Teeth
Hair
Case 36
What is glycogenic acanthosis?
Benign condition of the esophagus
- Nodular esophageal epithelium
- Occurs in elderly
- Not clinically important
Case 36
Most common cause of infectious esophagitis?
Candida albicans
Case 36
Esophageal papillomatosis is associated with which skin condition?
Acanthosis nigricans
Case 35
How often are ovarian dermoids bilateral?
15%
Case 36
What imaging feature distinguishes esophageal Candida infection in immunocompromised vs immunocompetent patient?
Immunocompromised
- shaggy esophagus
Immunocompetent
- nodular esophagus
Case 36
Name three skin conditions that are associated with multiple tiny esophageal nodular lesions
Acanthosis nigricans
Bullous pemphigoid
Pyoderma gangrenosum
Case 37
What is the definitive treatment for acalculous cholecystitis?
Cholecystectomy
Drainage of any associated abscess
Case 37
What conditions are associated with acalculous cholecystitis?
Surgery Trauma Shock Ischemia Mechanical Ventilation AIDS Burns Vasculitis Parenteral Nutrition
Case 38
What is the MC source of hematogenous mets to stomach?
Melanoma
Case 38
What is the MC site of melanoma mets to GI tract?
Small bowel
Case 38
In recent decades, what is the most common cause of bull’s eye lesions in the stomach?
Kaposi’s sarcoma
- AIDS
Case 38
Name five sources of metastasis to the stomach
Melanoma Lung Breast Kaposi's Sarcoma Lymphoma
Case 38
Define the classic bull’s eye lesion
Rounded filling defect with a barium collection at its center (ulceration)
Case 39
What polyposis syndrome is assoc with osteomas and cortical hyperostosis?
Familial Adenomatous Polyposis
- Gardner syndrome
- Now a part of FAPS
Case 39
Which polyposis syndrome is autosomal recessive inhertiance?
Cronkhite-Canada
All others are AD
- FAP / Gardner’s
- Peutz-Jegher’s Syn
- Cowden’s Syn
Case 39
What are clinical features of Cronkhite-Canada syn?
Rash
Alopecia
Diarrhea
Case 39
What are the two most common malignancies associated with polyposis syndromes?
Colon is most common
Periampullary carcinoma
- Thyroid increased in women
Case 39
Which polyposis syndrome is associated with CNS tumors such as glioblastomas and medulloblastomas?
Turcot’s Syndrome
Case 40
What is the most common etiology of colorectal carcinoma?
Adenoma
Case 40
Name 4 risk factors associated with colon cancer
Adenomatous polyp
Ulcerative colitis
Patient Diet
Family history
Case 40
How common is colon CA relative to other malignancies?
Fourth
Lung
Breast
Prostate
Colon
Case 41
What is the likely cause of GB wall calcification (porcelain GB)?
Chronic cystic duct obstruction with subacute inflammation
Case 40
What is the correlation between polyp size in the colon and chance of malignancy?
Less than 1 cm 1 %
1 to 2 cm 10 %
Over 2 cm 40%
Case 41
What is the MC complication of porcelain GB?
GB carcinoma (up to 30%)
Case 42
What conditions are associated with esophageal intramural pseudodiverticulosis?
- Strictures
- Candida esophagitis
- Other inflammatory conditions
Case 42
Describe Esophageal Intramural Pseudodiverticulosis
- Barium filling of exretory ducts of the mucous glands
- Normal anatomic structures
- Dilate due to underlying inflammatory process
- –> Fill with barium
- Commonly mistaken for ulcers
- Candida organisms commonly found in pts w/ this condition
- May result in benign strictures
- Slightly increased risk of adenocarcinoma
Case 43
How do malignant and benign pelvic lesions affect bowel differently?
Benign masses
- obstruct
Malignant masses
- invade adjacent serosal surface
Case 44
What fungal infection is known to be locally aggressive and breach fascial barriers?
Actinomycosis
Case 44
What would be the MC cause of psoas abscess worldwide?
Tuberculosis
Case 45
What is the MC specific histologic subtype of pancreatic malignancy
Ductal epithelial adenocarcinoma
Case 45
What is the most common clinical presentation of pancreatic cancer?
Pain
Case 45
Where are most pancreatic cancers located?
Head
Case 46
What is the best imaging modality to assess for local spread of gastric cancer?
Endoscopic ultrasound
Case 46
What percentage of gastric cancers are linitis plastica type?
About 10%
Case 46
What is the name of the association of gastric cancer metastatic to the left axilla?
Irish node
Case 47
What is the 2nd MC solid organ injured in blunt trauma?
Liver
Case 48
What is the moulage sign and what is it associated with?
Seen on SBFT. Barium forms smooth, featureless elongated columns or clumps in the jejunum.
Associated with celiac dz.
Case 49
What is the cause of feline esophagus?
Transient spasm of longitudinal muscularis mucosa
Case 48
What is the MC finding seen on SBFT in pts with celiac disease?
- Diffuse dilation of distal small bowel
2. Jejunization of ileum
Case 49
What is the MC symptom of eosinophilic esophagitis?
Solid dysphagia
Case 50
In diverticular hemorrhage, where is the diverticulum typically located?
Right colon
Case 49
What is the ‘ringed esophagus’ and what is it associated with?
A segment of fixed transverse folds
Eosinophilic esophagitis
Case 50
Are colonic diverticula true diverticula?
What is thought to be the pathogenesis of diverticulitis?
No
Infection secondary to impacted fecal matter
Case 50
What percentage of patients older than 60 in the U.S. have colonic diverticula?
60%
Case 51
Through what anatomic area does the hernia sac pass in a spigelian hernia?
Linea semilunaris
- Fibrous band of tissue joining the rectus with the oblique muscles
- Probably a result of weakness or congenital defect
Case 51
What is a Littre hernia?
A hernia containing a Meckel diverticulum
Case 52
What is the MC clinical manifestation of Crohn’s disease?
Diarrhea
Case 51
What is the unusual hernia which contains only a portion of the bowel loop and not the entire lumen?
Richter’s hernia!!
Important b/c it can incarcerate without obstruction
Case 52
DDx for wall thickening of the terminal ileum
Crohn’s
TB
Yersinia
UC -never involves TI but can appear patulous from backwash ileitis
Case 52
Cardinal presentation of Crohn’s
Diarrhea
Abdominal pain
Weight Loss
Case 52
What is the MC part of the GI tract involved in Crohn’s disease?
Small bowel
Commonly a string sign of the TI on a SBS
Case 53
What is filiform polyposis of the colon?
Diffuse colonic polyps in the colon secondary to chronic ‘burned out’ ulcerative colitis
Case 53
Most common acute complication of severe UC?
Toxic Megacolon
Case 54
What neoplasm most commonly produces thickened gastric folds?
Lymphoma
Case 54
What causes isolated gastric fundal varices?
Splenic vein thrombosis
Case 54
What is the MC infectious cause of thickened gastric folds?
H. pylori
Case 54
DDx for gastric fold thickening
Gastritis
- EtOH
- Eosinophilic
H. Pylori
Sarcoid
Amyloid
Crohn’s
Menetrier’s dz
Mets
Adeno CA
Zollinger- Ellison Syn
Case 54
What is Menetrier’s disease?
Rare disease characterized by gastric mucosal hypertrophy (giant rugal folds)
Achlorhydria, hypoproteinemia, and edema
Case 55
What lobe is typically spared in hepatic cirrhosis?
Caudate lobe
-derives blood supply from IVC
Case 56
How can radiating folds help determine whether a gastric ulcer is benign or malignant?
If the radiating fold extends to the center of the edge of the crater - it is most likely benign.
If it stops short, could be benign or malignant.
Case 57
What is required for GI carcinoid tumor to produce carcinoid syndrome?
Liver metastases
Case 56
Most common cause of benign gastric ulcer?
Does the size of an ulcer have any bearing on malignant potential?
H. Pylori
No
Case 57
How often are carcinoid tumors multiple?
20%
Case 56
What is a Hampton line sign and is the ulcer benign or malignant?
Thin lucent line at the base or neck of an ulcer
Indicates that the ulcer is benign
Case 57
What substance is produced by carcinoid tumors?
Serotonin
Case 57
What non-imaging test can be used to confirm the diagnosis of carcinoid?
Urine test for 5-HIAA
Case 57
What is the most common site from which carcinoid tumor arises?
Appendix
Case 58
What part of the bowel is typically affected with TB?
Viral infections?
TB - ileocecal area
Viral - colon
Case 58
What is the most common cause of viral colitis?
CMV
Case 59
What type of ulcer suggest Crohn’s dz rather than UC?
Aphthous ulcers
Case 59
What diseases produce bowel fistulae?
Crohn’s disease, diverticulitis (and rarely, TB)
Case 59
DDx for colonic fistula formation
Crohn’s
TB: Deep ulcers that progress to fistulae
Diverticulitis (colovesical)
- Fistulas are never seen w UC
Case 60
What are the tiny diverticula called in adenomyomatosis?
Rokitansky-Aschoff Sinuses
Case 59
What diseases are associated with long, linear mucosal ulcers?
Crohn’s
TB
Diverticulitis (colovesical)
- Fistulas are never seen w UC
Case 59
What diseases are associated with long, linear mucosal ulcers?
Crohn’s disease
TB rarely
Case 56
How can location of gastric ulcers help predict benignity?
Lesser curvature - tend to be benign
Fundus - tend to be malignant
Case 57
What is the MC site in the GI tract for carcinoid?
Appendix
Case 60
What is the clinical significance of GB adenomyomatosis?
None