GI Motility DSA Flashcards
What GI layer faces the lumen?
mucosal layer with the epithelial cells that have absorptive and secretion functions. also villi to increase surface area
What muscle layer is more densely innervated and its contraction shortens the diameter of the segment?
Circular smooth muscle layer
What muscle layer is thin with few nerve fibers and its contraction causes propulsion of food?
longitudinal smooth muscle layer (outer)
What is the importance of gap junctions in smooth muscle?
Cells electrically coupled via low resistance pathways
Permit rapid cell-to-cell spread of actions potential
Sympathetic stimulation by NE causes GI sm m to do what?
hyperpolarization - inhibiting
Parasympathetic stimulation by ACh causes GI sm m to do what?
increase amplitude of slow wave
cause depolarization
stimulating
Describe phasic contraction vs tonic contraction
Phasic: periodic contractions followed by relaxation
Tonic: constant level of contraction or tone without regular period of relaxation
What do subthreshold action potentials produce?
Small contraction/basal contractions
How many slow waves per minute occurs in the GI tract?
3 to 12
stomach 3 w/m
duodenum 12 w/m
Where do slow waves originate?
intestinal cells of Cajal