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GI Self > GI Micro > Flashcards

GI Micro Flashcards

1
Q

ANUG

A

Fusospirochetal Complex

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2
Q
A

ANUG

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3
Q

Aggressive periodontitis

A

Aggregatibacter Actinomycetemcomitans

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4
Q
A

Aggregatibacter Actinomycetemcomitans

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5
Q

Noma

A

Aggressive ANUG

Cancrum Oris

Gangrenous Stomatitis

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6
Q

Cervicofacial Actinomycosis

A

Actinomyces Israelii

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7
Q

Lumpy Jaw

A

Actinomyces Israelii

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8
Q
A

Actinomyces Israelii

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9
Q

Thrush

A

Candida

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10
Q
A

Candida

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11
Q
A

Porphyromonas Gingivalis

Prevotella Intermedia

Tannerella Forsythia

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12
Q

Chronic Periodontitis

A

Porphyromonas Gingivalis

Prevotella Intermedia

Tannerella Forsythia

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13
Q

Normal flora - possibly proctective

A

Veillonella Spp

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14
Q
A

Veillonella Spp

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15
Q
A

Primary colonizer of dental plaques

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16
Q

Actinomyces Viscosus

A

Primary colonizer of dental plaques

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17
Q

Shigella Disease

A

Dysentery

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18
Q

Shigella Characteristics

A

Gram negative

Rod

Non-sporulating

Facultative Anaerobe

Non-motile

Non-lactose fermenting

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19
Q

Dysentery

A

Watery to bloody diarrhea

Fever

Cramps

Tenesmus

Multiple shallow ulcers on scope - looks like IBD

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20
Q

Shigella Toxins

A

Pic -Mucus cleaving enterotoxin

Sig A - Cytotoxin

Sep A - Unknown

LPS - O antigen

Actin binding protein (uses cells own transporters)

Shigatoxin

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21
Q

Shiga toxin

A

60S ribosome inactivator

Endothelial dammage

Induce inflammatry cytokines

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22
Q

Shigella Complications

A

HUS - especially after ABx

Autoimmune disease

Reiter’s syndrome/reactive arthritis (HLA-B27)

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23
Q

Vibrio

A

Cholera

24
Q

Cholera

A

Profuse watery diarrhea

Cramps

Nausea/Vomitting

25
Q

Vibrio characteristics

A

Gram - comma shaped rod

Motile

Flagellated

Grows yellow on TCBS agar

26
Q

Vibrio Toxins

A

Cholera Toxin A and B - perm upregulate Adenylate cylcase

Heat labile enterotoxin

Ctx A is similar to LT in E. Coli

27
Q

Clostridium Characteristics

A

Gram postivie rod

Spore forming

Obligate anaerobe

Catalase negative

Oxidase negative

Motile

28
Q

C diff

A

Psuedomambranous colitis

Post antibiotics

Diarrhea - watery or bloody

Cramps, fever

Leukocytosis

29
Q

Clostridium Toxins

A

Toxin A - Enterotoxin increases secretion

Toxin B- Cytotoxin disrupts cytoskeleton

30
Q

Clostridium Perfringens Differences

A

Enterotoxin (like cdiff toxin A)

Without fever

Alpha toxin - Degrades cell mbe

Myonecrosis - Muscle breakdown (gas gangrene)

Double zone of hemolysis on blood agar

31
Q

Enterobacteriacea Characteristics

A

Gram negative rods

Catalse positive

Oxidase negative

Facultative anaerobe

Ferment glucose

Ferment lactose (E. coli)

32
Q

E. Coli

A

Travelers Diarrhea

Related to shigella

33
Q

SS Agar

A

Salmonella black centers

E. Coli Pink

Shigella Teal

34
Q

ETEC - Enterotoxigenic E. Coli

A

LT and ST cytotoxins

Travelers diarrhea

Foodborne or contaminated water supply

35
Q

AEEC- Attaching and effacing E. Coli

A

Destroy surface - form actin pedestals

Microvilli are effaced from surface

Enterocyte exfoliation

EPEC - Peds

STEC = Shigella like

36
Q

EHEC - Enterohemorrhagic

STEC

A

SHiga toxin producing

Zoonotic

Can cause HUS like shiga

37
Q

EAEC- Enteroaggregative E. Coli

A

Common in US

Acute or chronic

Dangerous in HIV

38
Q

EIEC- Enteroinvasive E. Coli

A

Dysentery like symptoms - bloody stool

Similar presentation to shigella (more so than EHEC???)

39
Q

Heat stabile proteins

A

Released upon lysis

STa/b - Hypersecretion and malaboption

EAST1 - Enhances effect of other toxins

40
Q

Campylobacter Characteristics

A

Gull-winged shaped (spiral)

Gram negative

Microaerophilic (strict)

Grows in high heat

Oxidase positive

Catalase variable

Grows on Skirrow agar

41
Q

Campylobacter enteritis

A

Severe Abd pain

Fever

Watery to dysentery (sometimes)

Reactive arthritis

Guillan-Barre

42
Q

Campylobacter toxicity

A

Major outer mbe protein (adhesion)

Cholera-like toxin = enterotoxin (increases cAMP)

Cytolethal distending toxin (DNAse) - distends host cells

S. Layer (sweater layer)

43
Q

Yersinia Enterocolitica

A

Emerging diarrheal pathogen

Enteric like illness

May mimic appendicitis

44
Q

Enterococcus

A

VRE (e. faecalis, e. faecium)

45
Q

Salmonella

A

Fever, cramps, diarrhea, vomiting

2-3 duration

Shed for weeks

46
Q

Salmonella characteristics

A

Gram negative rod

Non-spore forming

Facultative Anaerobe

Motile

Does not ferment lactose

47
Q

S. enterica typhi, typhimurium, enteritidis

A

Typhoid fever

Septic

Enterocolitis

48
Q

SS Agar - Salmonella

A

Black growth - especially in center of colony

49
Q

Clostridium botulinum

A

Toxin A, B, E, and F

Intoxication

Cleaves SNARE proteins which prevents exocytosis of neurotransmitters

50
Q

Clostridium Boltulinum Characteristics

A

Gram positive bacilli

Obligate anaerobe

Endospore in soils and H20

51
Q

Botulism vectors

A

Bulging cans and honey

52
Q

Bacillus Cerus

A

Espec. Rice linked to vomitting illness

Veggies/meat linked to diarrheal

53
Q

B. Cerus Characteristics

A

Gram positive sporultation

Motile

No Capsule

54
Q

Listeria Monocytogenes

A

Bacteria highly resistant to food safety

Food sickness

Granulomatosis infantiseptica

Meningitis

55
Q

Listeria Characteristics

A

Gram positive

Non-sporulating

Catalase positive

Motile - actin binding

Growth in wide range of environments

End-over-end motility at room temp

56
Q

Granulomatosis infantiseptica

A

In utero infection

Neonatal sepsis

Pustular lesions

Granulomas with listeria inside

GI Self (2 decks)

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