GI Meds Flashcards

1
Q

What is the MOA of stimulant laxatives

A

increases acetylcholine-regulated GI motility (peristalsis) and alters electrolyte transport in the mucosa

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2
Q

What is the MOA of fiber

A

retains water and improves GI transit

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3
Q

What is the MOA of osmotic laxatives

A

Causes H20 retention in stool (osmotic effect pulls H20 into gut)

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4
Q

What is the MOA of bulk forming laxatives

A

Absorbs water and increases fecal mass (increases frequency and softens the consistency of stool with minimal effects)

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5
Q

Lactulose is a

A

osmotic laxative

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6
Q

Bisacodyl is a

A

stimulant laxative

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7
Q

What dextran is a

A

bulk forming laxative

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8
Q

Psyllium is a

A

bulk forming laxative

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9
Q

Sorbitol is a

A

osmotic laxative

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10
Q

Methylcellulose is a

A

bulk forming laxative

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11
Q

Senna is a

A

stimulant laxative

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12
Q

What are the 2 types of saline laxatives and what “class” do they fall under

A

Milk of magnesia, Magnesium citrate

osmotic laxatives

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13
Q

Polycarbophil is a

A

bulk forming laxative

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14
Q

Polyethylene glycol (PEG) is a

A

osmotic laxative

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15
Q

Psyllium, methylcellulose, polycarbophil, and wheat dextran are:

A

bulk forming laxatives

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16
Q

PEG, lactulose, sorbitol, milk of magnesia, and magnesium citrate are:

A

osmotic laxatives

17
Q

Bisacodyl and Senna are:

A

stimulant laxatives

18
Q

What are the adverse effects of bulk forming laxatives

A

Flatulence, bloating

19
Q

What are the adverse effects of PEG

A

Flatulence, bloating

20
Q

What are the adverse effects of sorbitol

A

Bloating, flatulence (cheap synthetic sugar)

21
Q

What are the adverse effects of milk of magnesia and magnesium citrate?

A

Hypermagnesemia (esp. with chronic renal disease)

22
Q

What are the adverse effects of stimulant laxatives

A

Diarrhea, abdominal pain