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Medicines (Stage 2) > GI Meds > Flashcards

GI Meds Flashcards

1
Q

What are the GI meds for Stage 2?

A
  • H.Pylori eradication therapy (Amoxicillin, Clarithromycin or metronidazole)
  • Ibuprofen
  • PPIs
  • Sodium alginate (Gaviscon)
  • Senna
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2
Q

How is a H.Pylori infection usually treated with

A
  • Without penicillin allergy: PPI, amoxicillin and either clarithromycin or metronidazole
  • With penicillin allergy: PPI, clarithromycin and metronidazole.
  • Need to consider previous treatment with antibiotics
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3
Q

What are contraindications and side effects of Clarithromycin

A
  • dizziness, GI discomfort, dry mouth.
  • Contraindcation with DOACs (monitor side effects), CCB (monitor+adjust), statin (avoid/adjust rhabdomyolysis), Corticosteroid (monitor adverse effects), salbutamol (avoid)
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4
Q

What are some councelling points for Clarithromycin?

A
  • Make sure to take the complete the treatment as prescribed. Antibiotic resistance and return if no improvement in symptoms in 3 days
  • Can take with food
  • Alcohol in moderation unlikely to cause harm
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5
Q

What are some contraindications and side effects of Metronidazole

A
  • Dont drink alcohol until 48hrs after treatment
  • Side effects: nausea, vomiting, GI discomfort
  • Contraindication with warfarin - monitor INR + adjust dose
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6
Q

What are some counselling points for Metronidazole

A
  • Take with or after food with a full glass of water and don’t drink alcohol until 48hrs after stopping
  • Make sure to take full course of treatment and return if no improvement in 3 days
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7
Q

What are the contraindications and side effects of amoxicillin

A
  • Do not give with penicillin allergy
  • Contraindicated with warfarin (monitor INR and adjust dose)
  • Side Effects: Diarrhoea, nausea, skin reactions
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8
Q

What are the counselling points for amoxicillin

A
  • Take with/without food
  • Alcohol in moderation is unlikely to cause problems
  • Take full prescribed dose
  • Return if no improvement in 3 days/ worsening
  • Rash - medical advice
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9
Q

What are the indications of Ibuprofen

A
  • Pain and inflammation musculoskeletal disorders, pain
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10
Q

What are some contraindications and side effects of Ibuprofen

A
  • Stop in active gastrointestinal bleeding and AKI
  • Side Effects: GI discomfort, dizziness, skin reactions
  • Contraindications with DOACs, Aspirin, Beclomethasone, diuretics, Warfarin, ACE (nephrotoxicity)
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11
Q

What are some counselling points for Ibuprofen

A
  • If any sign of stomach discomfort/pain. Ask about stools and bleeding. Refer + stop ibuprofen
  • Should take a lowest dose for the shortest duration to avoid side effects
  • Take with a meal - less likely for side effects + avoid lying down after taking
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12
Q

What are the indications for PPIs

A
  • Helicobacter Pylori Infection
  • Gastric and duodenal ulcers
  • GORD/ Oesophagitis
  • Dyspepsia
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13
Q

What are some examples of PPIs

A
  • Omeprazole
  • Esomeprazole
  • Lansoprazole
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14
Q

What are some contraindications and side effects of PPIs

A
  • Rebound Hypersecretion: more acid after stopping
  • Osteoporotic fractures
  • Hypomagnaesia
  • Side Effects: Abdominal pain, dizziness, headache
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15
Q

What are some counselling points of PPIs

A
  • Measurement of serum magnesium should be considered in prolonged treatment
  • Dont stop abruptly - rebound hypersecretion
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16
Q

What are the indications of Gaviscon

A
  • Dyspepsia and GORD
17
Q

What are the contraindications and side effects of gaviscon

A
  • Dont take ibuprofen or aspirin with it
  • Long term use not recommended in GORD
  • Can increase salt levels in body
18
Q

What are the counselling points of Gaviscon

A
  • Take after meals or at bedtime
  • Do not double dose
19
Q

What is the indication of Senna

A
  • Constipation
20
Q

What are the contraindications and side effects of Senna

A
  • Side effects: GI discomfort, diarrhoea, electrolyte imbalances
  • Prolonged use can cause hypokalaemia

Medicines (Stage 2) (3 decks)

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