GI Histology Flashcards

1
Q

What type of epithelium lines the oral cavity

A

stratified squamous

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2
Q

What type of epithelium lines the esophagus

A

stratified squamous

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3
Q

What type of epithelium lines the stomach

A

simple columnar

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4
Q

What type of epithelium lines the intestines

A

simple columnar

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5
Q

which layer of the mucosa is home to a lareg number of leukocytes

A

lamina propria

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6
Q

What layer separates the mucosa from the submucosa

A

Muscularis mucosae

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7
Q

Miessner’s plexus is located where

A

In the submucosa

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8
Q

Muscle layers in the muscularis externa (exception: stomach)

A

Inner circular

Outer longitudinal layer

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9
Q

Aurbach’s plexus is located where

A

in the muscularis externa between the inner circular and outer longitudinal layer

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10
Q

Serosa vs Adventitia

A
Serosa = in the peritineal cavity 
Adventitia = outside the peritneal cavity (whispy fibers that blend with surrounding connective tissue)
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11
Q

Serosa is made up of what type of epithelium

A

Simple squamous

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12
Q

Which layers are missing in the oral cavity>?

A

Muscularis Mucosa
Muscularis Externa
Serosa/adventitia

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13
Q

Minor salivart glads

A

intrinsic
mucous secreting
branched tubular

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14
Q

mucous secreting glands of the oral cavity

A

mostly watery part of saliva not very many enzymes

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15
Q

lingual papillae of the tongue

A

Filiform
Fungiform
Circumvallate
Foliate

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16
Q

Filiform papilla

A
most abundant 
mostly anterior 
Highly keratinized 
Mechanical function (grab onto food) 
NO TASTE BUDS
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17
Q

Fungiform papillae

A

mushroom shaped most abundant near the tip of the tonge

taste bud located at apical surface

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18
Q

Circumvallate papillae

A

row of saucer shaved papillae that for the V in front of the terminal sulcus
tastebuds placed laterally within the surrounding moat
Von Ebners glands open at the base of the moat and secrete watery saliva to flush the moat

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19
Q

Foliate papillae

A

parallel ridge that run on the side of the tongue, laterally placed tased buds, moat with vonebners glands between the ridges

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20
Q

Cell types within tase buds

A

sensory - modified neuron

Support cells - fibroblasts

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21
Q

where are taste buds located

A

tongue (fungiform, circumvallate, foliate) oral cavity (glossopharyngeal arch, soft palate, Epiglottis)

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22
Q

Functions of Saliva

A

lubricates oral cavity
Digestive enzymes (amylase -cabs, lipase- fats)
Antibacterial
Immune - IgA
Source of calcium and phosphate ions essential for normal tooth development

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23
Q

Are major salivary glands intrisnic or extrinsic

A

Extrinsic

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24
Q

Three components of major salivary glads

A

Stroma
Secretory part
Ductal system

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25
Q

three types of acini within the secretory part of major salivary glands

A

Serous Acini
Mucous Acini
Mixed Acini

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26
Q

Serous Acini of major salivary glands

A

Protein secreting:
Euchromatic nucleaus, dark basophillic base due to abundant RER, lighter staining (orange) granules in apical domain

Pyramidal shaped cells - gland is spherical in shape

27
Q

Mucous acini of major salivary glands

A

mucous secreting:

Heterochromatic nucli that are squished at the base. Frothy appearance

28
Q

Mixed acini of major salivary glands

A

tubular mucous component with serous cap (seorus demilune)

29
Q

Myoepithelial cells of major salivary glands

A

nonsecreting cells within the acini

contractile cells that embrace the basal part of acinar secretory cells

30
Q

Subdivisions of intralobule ducts in major salivary glands

A
  1. Interacalated

2. Striated

31
Q

Intercalated ducts of major salivary glands

A

intra lobular
begins directly from the acini
lined with low cuboidal
nuclei near the base

32
Q

what kind of epithelium line intercalated ducts

A

low cuboidal

33
Q

Striated ducts of major salivary glands

A

Columnar epithelial cells
Basal membrane infoldings
nuclei in the midd part of the cell (pushed up by basal infoldings

34
Q

type of columnar epithelium lining striated ducts of major salivary glands

A

columnar

35
Q

Purpose of basal membrane inflodings within striated ducts of major salivary glands

A

increase surface area for ion absorption
Pumps transport ions into saliva AGAINST they gradient
Mictochondria are stacked in the infoldings to provide ATP for the pumps

36
Q

what kind of epithelium lines interlobular ducts of major salivary glands

A

Stratifed colimnar (can also be simple columnar and stratifed cuboidal)

37
Q

Which of the major salivary glands is completely serous?

A

parotid

38
Q

Which of the major salivary glands is mixed but is mostly serous?

A

Submandibular

39
Q

Which of the major salivary glands is mixed but is mostly mucous

A

Sublingual

40
Q

three major salivary glands

A

parotid
submandibular
sublingual

41
Q

what is unique about the muscularis mucosae of the esophagus?

A

longitudinally oriented bundles of smooth muscle separated by connective tissue

42
Q

Mucosal (esophageal cardiac glands)

A

present in the terminal part of the esophagus

43
Q

Esophageal glands proper

A

located in the submucosa
tubuloalveolar glands
scattered along the length of the esophagus

44
Q

serosa/adventitia of the esophagus

A

mostly adventitia

very distal part that projects through the hiatus of the diaphragm (serosa)

45
Q

Functions of the stomach

A

storage of food
digestion
regulation of GI hormones

46
Q

what layers form the rugae of the stomach

A

mucosa and submucosa fold into rugae

47
Q

Histological regions of the stomach

A
  1. Cardiac region (contains cardiac glands)
  2. Fundic region (contains fundic glands)
  3. Pyloric region (contains pyloric glands)
48
Q

surface mucosal cells

A

mucosa of the stomach (simple columnar)

secrete tough, thick, gel like mucous that forms a coat that protects the epithelium from HCl

49
Q

Gastric pits

A

located on surface epithelium- lined with surface mucous cells

50
Q

how does the lamina propria differ in the stomach from other region?

A

unique glands (depending on area- cardiac, fundic, pyloric)

51
Q

what makes muscularis externa unique in the stomach

A

three layers instead of 2

inner oblique
middle circular layer
outer longitudinal

52
Q

Parietal cells

A

mostly found in the neck of the fundic gland
“Fried egg” appearance

produces HCl

Proceds intrinsic factor

53
Q

Secreting vs nonsecreting parietal cell

A

Secreting - microvilli extend into inracellular canaliculi to increas surace area to pump H and Cl

non-secreting- folds down into tubovesicular system

54
Q

gastric cells

A

located in the base of the fundic gland

protein secreting cell- abdundant RER at base, secretory granules in the apical portion

secrete pepsiongen

55
Q

Mucous neck cells

A

located in the neck of the fundic glands

secretion of soluble mucous to dilute secretions and create a smooth environment

56
Q

enteroendocrine cells

A

concentrated at the base of fundic glands

secrete gastrin and ghrelin

secrete to lamina propria

57
Q

Pogenitor cells

A

located in the isthmus of the gland

replace both mucous cells and fundic gland cells

58
Q

Fundic gland cells

A
Parietal cells 
gastric cheif cells 
enteroendocrine cells 
mucous neck cells 
Porgenitor cells
59
Q

Cadiac gland cells

A

narrow ring around esophageal orifice

Branched tubular

produces muscous that protect the esophogeal eipthelim form acid reflux

shallow gastric pits (less than 1/2 depth of mucosa)

60
Q

Pyloric Glands

A

located in pyloric antrum

Branched coiled

produce mucous that protects the pyloric mucosa

gastric pits extend beyond 1/2 depth of mucosa

61
Q

Functions of the small intestine

A
Principle site of digestion of food 
absorption 
synthesis and secretion of digestive enzymes 
control of microbial growth 
regulation of GI function
62
Q

Plicae Circularis

A

unique feature of the small intestine

core contains both mucosa and submucoa

most numerous in the distal duodenum and proximal jejunum

63
Q

Villi

A

unique feature to the small intestine

core formed by connective tissue and lamina propria