GI High Yield HO Flashcards

1
Q

differential dx for hematochezia

A
hemorrhoids
anal fissures
diverticular bleed
IBD
infectious colitis
ischemic colitis
AV malformation
rapid upper GIB
polyps 
rectal ulcers
colorectal cancer
radiation colitis
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2
Q

painless bleeding associated with bowel movement, coats the stool at the end of the defecation. blood may also drip into the toilet or stain toilet paper

A

hemorrhoids

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3
Q

dx from the hx, tearing pain with the passage of bowel movements, a small amount on the toiilet paper or on the surface of stool

A

anal fissures

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4
Q

which IBD is more likely to present with hematochezia

A

ulcerative colitis

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5
Q

hematochezia developed weeks to years after abdominal or pelvic irradiation

A

radiation colitis

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6
Q

what are important history and physical points to ask/perform on a GIB patient

A

prior episodes of GI bleeding?
pregnancy?
hx of IBD, cancer, CV disease, diverticulosis, PUD
medications - NSAIDS, anticoagulants, antiplatelets
PE - assess hemodynamic stability - look for signs of hypovolemia
general exam - CP, skin, abdominal, DRE

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7
Q

signs of hypovolemia include

A

mild to moderate hypovolemia will present with resting tachycardia
15% blood volume loss - orthostatic hypotension (decrease in systolic of more than 20 mmhg and/or increase in HR of 20bpm when moving from recumbency to standing)
40% decrease - supine hypotension

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8
Q

medications of interest in GIB patients

A

NSAIDS
anticoagulants
antiplatelets

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9
Q

ulcerative colitis assocation with smoking

A

stopping smoking is a risk factor for UC

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10
Q

crohn disease assocaition with smoking

A

starting smoking can induce flare or first episode

continued smoking leads to a poorer prognosis

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11
Q

bun:cr ratio in upper GIB patients

A

30:1

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12
Q

ast:alt ratio in an alcoholic

A

2:1

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13
Q

anatomical division between the upper GI and lower GI

A

ligament of trietz

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14
Q

pt abruptly stops using a beta blocker – what are they at risk of developing

A

rebound sinus rhythm

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15
Q

what dx study should be performed in any femal of child-bearing age with abdominal pain?

A

pregnancy test

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16
Q

fastest rate K can be given in a peripheral IV

A

10mEq/hour

otherwise it is irritating

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17
Q

how many g/dl would you expect hemoglobin to rise after infusing 1 unit of PRBCs

A

1 unit should raise Hgb by 1g/dL

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18
Q

primary tx for acute IBD flare up

A

corticosteroids

IV or PO

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19
Q

red nodular areas on the shins seen in many inflammatory conditions

A

erythema nodosum

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20
Q

initial management of an acute lower GIB

A

supportive: IV ccess, appropriate setting (outpatient/inpatient/ICU) O2, IVF, blood products, assessment and management of coagulopathies
in patients with ongoing bleeding or high risk clinical features
colonoscopy w/in 24h

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21
Q

before recieving a colonoscopy, what should be patients be adminsitered

A

4-6L of PEG

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22
Q

if patient presenting with a subacute GIB has a stable

but low hemoglobin, how should you manage

A

type and screen

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23
Q

at what hemoglobin level do young patients without cormorbid illness recieve transfusion

A

< 7 g/dL

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24
Q

at what hemoglobin level do older patients with comorbid illnesses such as CAD require transfusion

A

<9 g/dL

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25
before transfusing any PRBCs, what lab test should you perform?
iron studies | otherwise they will be inaccurate
26
pros to radionuclide imaging
noninvasive sensitive to low rates of bleeding can be repeated for intermittent bleeding cons - has to be performed during active bleeding poor localization of bleeding site not widely available
27
pros to CT angiography
noninvasive accurately localizes bleeding source provides anatomic detail widely available cons - has to be performed during active bleeding not therapeutic radation and IV contrast exposure
28
pros to angiogrpahy
localization therapy w/ super selective embolization does not require bowel prep cons active bleeding potential for serious complicatiosn
29
pros to colonoscopy
precise dx and therapeutic endoscopic therapy is possible cons - need to prep colon - risk of sedation in acutely bleeding patient definite bleeding source infrequently IDd
30
patients with UC are at an increased risk for what complications?
toxic megacolon PSC ankylosing spondylitis pyoderma gangrenosum colon cancer and DVT
31
pt with crohns are at an increased risk for what complications
``` fistulas/strictures fissures pigmented gallstone formation malabsorption kidney stones ``` colon cancer and DVT
32
grey turner sign and cullen sign are two clinical signs of what event
retroperitoneal hemorrhage cullen - periumbilical ecchy grey turner - flank ecchy
33
people who are in good health, with no risk factors, and with a life expectancy of more than 10 years are recommended to get colorectal cancer screening how often?
beginning at age 45, every 10 years until 75
34
people ages 76-85 recommendation for colorectal cancer screening
decision to be screening should be based on a persons preferences, life expectancy, overall health and prior screening hx
35
at what age are patients no longer recommended to get colorectal cancer screening?
over 85
36
risk factors for colorectal cancer
personal hx of colorectal cancer or certain polyps family hx of colorectal cancer personal hx of IBD confirmed or suspected FAP or lynch hx of radiation to the abdomen or pelvic area to treat prior cancer
37
if you have a first degree relative with colorecgtal cancer/adenoma diagnosted before 60 or two first degree relative of any age, when should you start getting screened for colorectal cancer?
40, or 10 years before first diagnosis in relative, whichever is sooner
38
if you have a first degree relative who had colorectal cancer after the age of 60 or two second degree relatives with colorectal cacner, when should you start getting screened for colorectal cancer?
start at 40
39
patients at risk of inherited FAP should begin screening at?
sigmoidoscopy at 10-12, with genetic testing
40
patients at risk of inherited HNCC should begin screening at what age?
20-25 or 10 years younger than youngest age of colorectal cancer dx in family colonoscopy every 2 years concurrent genetic testing
41
stool based tests for colorectal cancer screening?
gFOBT FIT FIT-DNA
42
direct visualization tests for colorectal cancer screening?
colonoscopy ***** CT colonoscopy flexible sigmoidoscopy flexible sigmoidoscopy with FIT
43
gold standard for colorectal cancer screening
colonoscopy
44
crohns or UC: mucosal layer only
UC
45
crohns or UC: transmural thickness affected
crohns
46
crohns or UC: affects only the colon
UC
47
crohns or UC: continuous lesinos
UC
48
crohns or UC: skip lesions
crohns
49
crohns or UC: occurs anywhere along the GI tract
crohns
50
crohns or UC: ASCA positive
crohns
51
crohns or UC: pANCA positive
UC
52
crohns or UC: noncaseating granulomas
crohns
53
crohns or UC: blood diarrhea is common
UC
54
crohns or UC: crypt abcesses on histology
UC
55
crohns or UC: strictures and obstructions
crohns
56
crohns or UC: weight loss, fistulas, peri-anal disease
corhns
57
crohns or UC: aphthous ulcers
crohns
58
crohns or UC: pseudopolyps
UC
59
crohns or UC: toxic megacolon
UC
60
crohns or UC: creeping fat and cobblestoning
crohns
61
crohns or UC: smoking is protective
UC
62
crohns or UC: smoking worses the dz
crohns
63
prophylaxis for DVT
sequential compression stockings/devices TED hose anticoagulation early ambulation
64
before starting an immunomodulatory or biologic medication, waht should be checked?
TPMT enzyme activity before azathiopurine PPD skin test or quantiferon gold to check for TB viral hepatitis serology
65
risk factors for AAA
65+ male hx of smoking first degree relative with hx of AAA
66
iv, not hooked up to any infusion, flushed with saline and then locked
saline lock
67
iv, not hooked up to any infusion, flushed with heparin then locked
heparin lock
68
hooked up to infusion at slo rate
KVO
69
maintenance IVF
125cc/hr
70
rapid rehydration IVF volume
1L bolus
71
unnaceptable treatment for jehovahs witnesses
transfusion of allogeneic whoel blood, red blood cells, white blood cells, platelets or plasma preoperative autologous blood donation