GI High Yield HO Flashcards

1
Q

differential dx for hematochezia

A
hemorrhoids
anal fissures
diverticular bleed
IBD
infectious colitis
ischemic colitis
AV malformation
rapid upper GIB
polyps 
rectal ulcers
colorectal cancer
radiation colitis
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2
Q

painless bleeding associated with bowel movement, coats the stool at the end of the defecation. blood may also drip into the toilet or stain toilet paper

A

hemorrhoids

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3
Q

dx from the hx, tearing pain with the passage of bowel movements, a small amount on the toiilet paper or on the surface of stool

A

anal fissures

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4
Q

which IBD is more likely to present with hematochezia

A

ulcerative colitis

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5
Q

hematochezia developed weeks to years after abdominal or pelvic irradiation

A

radiation colitis

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6
Q

what are important history and physical points to ask/perform on a GIB patient

A

prior episodes of GI bleeding?
pregnancy?
hx of IBD, cancer, CV disease, diverticulosis, PUD
medications - NSAIDS, anticoagulants, antiplatelets
PE - assess hemodynamic stability - look for signs of hypovolemia
general exam - CP, skin, abdominal, DRE

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7
Q

signs of hypovolemia include

A

mild to moderate hypovolemia will present with resting tachycardia
15% blood volume loss - orthostatic hypotension (decrease in systolic of more than 20 mmhg and/or increase in HR of 20bpm when moving from recumbency to standing)
40% decrease - supine hypotension

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8
Q

medications of interest in GIB patients

A

NSAIDS
anticoagulants
antiplatelets

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9
Q

ulcerative colitis assocation with smoking

A

stopping smoking is a risk factor for UC

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10
Q

crohn disease assocaition with smoking

A

starting smoking can induce flare or first episode

continued smoking leads to a poorer prognosis

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11
Q

bun:cr ratio in upper GIB patients

A

30:1

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12
Q

ast:alt ratio in an alcoholic

A

2:1

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13
Q

anatomical division between the upper GI and lower GI

A

ligament of trietz

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14
Q

pt abruptly stops using a beta blocker – what are they at risk of developing

A

rebound sinus rhythm

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15
Q

what dx study should be performed in any femal of child-bearing age with abdominal pain?

A

pregnancy test

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16
Q

fastest rate K can be given in a peripheral IV

A

10mEq/hour

otherwise it is irritating

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17
Q

how many g/dl would you expect hemoglobin to rise after infusing 1 unit of PRBCs

A

1 unit should raise Hgb by 1g/dL

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18
Q

primary tx for acute IBD flare up

A

corticosteroids

IV or PO

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19
Q

red nodular areas on the shins seen in many inflammatory conditions

A

erythema nodosum

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20
Q

initial management of an acute lower GIB

A

supportive: IV ccess, appropriate setting (outpatient/inpatient/ICU) O2, IVF, blood products, assessment and management of coagulopathies
in patients with ongoing bleeding or high risk clinical features
colonoscopy w/in 24h

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21
Q

before recieving a colonoscopy, what should be patients be adminsitered

A

4-6L of PEG

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22
Q

if patient presenting with a subacute GIB has a stable

but low hemoglobin, how should you manage

A

type and screen

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23
Q

at what hemoglobin level do young patients without cormorbid illness recieve transfusion

A

< 7 g/dL

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24
Q

at what hemoglobin level do older patients with comorbid illnesses such as CAD require transfusion

A

<9 g/dL

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25
Q

before transfusing any PRBCs, what lab test should you perform?

A

iron studies

otherwise they will be inaccurate

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26
Q

pros to radionuclide imaging

A

noninvasive
sensitive to low rates of bleeding
can be repeated for intermittent bleeding

cons - has to be performed during active bleeding
poor localization of bleeding site
not widely available

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27
Q

pros to CT angiography

A

noninvasive
accurately localizes bleeding source
provides anatomic detail
widely available

cons - has to be performed during active bleeding
not therapeutic
radation and IV contrast exposure

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28
Q

pros to angiogrpahy

A

localization
therapy w/ super selective embolization
does not require bowel prep

cons
active bleeding
potential for serious complicatiosn

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29
Q

pros to colonoscopy

A

precise dx and therapeutic
endoscopic therapy is possible

cons - need to prep colon - risk of sedation in acutely bleeding patient
definite bleeding source infrequently IDd

30
Q

patients with UC are at an increased risk for what complications?

A

toxic megacolon
PSC
ankylosing spondylitis
pyoderma gangrenosum

colon cancer and DVT

31
Q

pt with crohns are at an increased risk for what complications

A
fistulas/strictures
fissures
pigmented gallstone formation
malabsorption
kidney stones 

colon cancer and DVT

32
Q

grey turner sign and cullen sign are two clinical signs of what event

A

retroperitoneal hemorrhage
cullen - periumbilical ecchy
grey turner - flank ecchy

33
Q

people who are in good health, with no risk factors, and with a life expectancy of more than 10 years are recommended to get colorectal cancer screening how often?

A

beginning at age 45, every 10 years until 75

34
Q

people ages 76-85 recommendation for colorectal cancer screening

A

decision to be screening should be based on a persons preferences, life expectancy, overall health and prior screening hx

35
Q

at what age are patients no longer recommended to get colorectal cancer screening?

A

over 85

36
Q

risk factors for colorectal cancer

A

personal hx of colorectal cancer or certain polyps
family hx of colorectal cancer
personal hx of IBD
confirmed or suspected FAP or lynch
hx of radiation to the abdomen or pelvic area to treat prior cancer

37
Q

if you have a first degree relative with colorecgtal cancer/adenoma diagnosted before 60 or two first degree relative of any age, when should you start getting screened for colorectal cancer?

A

40, or 10 years before first diagnosis in relative, whichever is sooner

38
Q

if you have a first degree relative who had colorectal cancer after the age of 60 or two second degree relatives with colorectal cacner, when should you start getting screened for colorectal cancer?

A

start at 40

39
Q

patients at risk of inherited FAP should begin screening at?

A

sigmoidoscopy at 10-12, with genetic testing

40
Q

patients at risk of inherited HNCC should begin screening at what age?

A

20-25 or 10 years younger than youngest age of colorectal cancer dx in family colonoscopy every 2 years
concurrent genetic testing

41
Q

stool based tests for colorectal cancer screening?

A

gFOBT
FIT
FIT-DNA

42
Q

direct visualization tests for colorectal cancer screening?

A

colonoscopy *****
CT colonoscopy
flexible sigmoidoscopy
flexible sigmoidoscopy with FIT

43
Q

gold standard for colorectal cancer screening

A

colonoscopy

44
Q

crohns or UC: mucosal layer only

A

UC

45
Q

crohns or UC: transmural thickness affected

A

crohns

46
Q

crohns or UC: affects only the colon

A

UC

47
Q

crohns or UC: continuous lesinos

A

UC

48
Q

crohns or UC: skip lesions

A

crohns

49
Q

crohns or UC: occurs anywhere along the GI tract

A

crohns

50
Q

crohns or UC: ASCA positive

A

crohns

51
Q

crohns or UC: pANCA positive

A

UC

52
Q

crohns or UC: noncaseating granulomas

A

crohns

53
Q

crohns or UC: blood diarrhea is common

A

UC

54
Q

crohns or UC: crypt abcesses on histology

A

UC

55
Q

crohns or UC: strictures and obstructions

A

crohns

56
Q

crohns or UC: weight loss, fistulas, peri-anal disease

A

corhns

57
Q

crohns or UC: aphthous ulcers

A

crohns

58
Q

crohns or UC: pseudopolyps

A

UC

59
Q

crohns or UC: toxic megacolon

A

UC

60
Q

crohns or UC: creeping fat and cobblestoning

A

crohns

61
Q

crohns or UC: smoking is protective

A

UC

62
Q

crohns or UC: smoking worses the dz

A

crohns

63
Q

prophylaxis for DVT

A

sequential compression stockings/devices
TED hose
anticoagulation
early ambulation

64
Q

before starting an immunomodulatory or biologic medication, waht should be checked?

A

TPMT enzyme activity before azathiopurine
PPD skin test or quantiferon gold to check for TB
viral hepatitis serology

65
Q

risk factors for AAA

A

65+
male
hx of smoking
first degree relative with hx of AAA

66
Q

iv, not hooked up to any infusion, flushed with saline and then locked

A

saline lock

67
Q

iv, not hooked up to any infusion, flushed with heparin then locked

A

heparin lock

68
Q

hooked up to infusion at slo rate

A

KVO

69
Q

maintenance IVF

A

125cc/hr

70
Q

rapid rehydration IVF volume

A

1L bolus

71
Q

unnaceptable treatment for jehovahs witnesses

A

transfusion of allogeneic whoel blood, red blood cells, white blood cells, platelets or plasma
preoperative autologous blood donation