GI Emergencies - McGowan Flashcards

1
Q

Hematemesis associated with alcohol use and persistent vomiting, in an otherwise healthy person is most likely _

A

Mallory Weiss tear

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2
Q

GI Ulcer associated with elevated intracranial pressure

A

Cushing’s ulcer

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3
Q

GI ulcer associated with severe burn

A

Curling ulcer

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4
Q

what is red wale marking

A

endoscopic sign suggestive of recent hemorrhage, or propensity to bleed, seen in people with esophageal varices

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5
Q

best initial treatment of active bleed to lower risk of rebleeding of the esophagus

A

Variceal banding

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6
Q

what is fetor hepaticus

A

aka breath of the dead or hepatic foetor, seen in portal HTN where portosystemic shunting allows thiols to pass directly into lungs

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7
Q

Upper GI bleed is proximal to

A

ligament of Treitz

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8
Q

Common causes of upper GI bleed

A
  1. peptic ulcer disease (MOST COMMON)
  2. Portal HTN
  3. mallory-Weiss Tears
  4. Angiodysplasias
  5. Telangiectasias
  6. Dieulfoy lesion
  7. Neoplasms
  8. Erosive gastritis
  9. Aortoenteric fistula
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9
Q

Systemic blood pressure lower than _ is at high risk of acute bleed

A

100

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10
Q

T or F: pt with acute bleed needs to have one 18 gauge or larger IV lines

A

False. Needs to have two*

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11
Q

Pt with BUN:Cr 30:1 with no renal issues, think what

A

Upper GIB - absorption of blood nitrogen from small intestine and prerenal azotemia

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12
Q

If a patient shows hemodynamic compromise or overt active bleed, what is the first thing you should try to fix?

A

Replenish fluid with 0.9 % (Normal) saline or LR

- type and cross match 2-4 units of PRBCs

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13
Q

Pt with active bleed, packed RBC should be given to maintain hbg at what level?

A

7-9

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14
Q

when is blood transfusion indicated in a GIB pt?

when is platelet transfuction indicated? plasma?

A

Transfuse blood in an actively bleeding pt whose hgb is below 7.
Transfuse platelet if count is <50,000
Transfuse fresh frozen plasma if pt has coagulopathy with INR > 1.8

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15
Q

EGD are usually safe with INR less than

A

2.5

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16
Q

what are clinical predictors of increased risk of rebleeding and death?

A
  • age over 60
  • comorbid illnesses
  • SBP <100
  • HR >100
  • bright red blood in NG aspirate or on rectal exam
17
Q

Virtually all patients with UGIB should undergo _ within 24 hrs of arriving to ED

A

endoscopy

18
Q

Portal HTN pts with UGIB should be given what meds?

A

PPI plus IV octreotide which reduces splanchnic blood flow and decreases portal blood pressure

19
Q

when is transvenous intrahepatic portosystemic shunts (TIPS) indicated?

A

in liver patient that fails endoscopic modalities

20
Q

when is surgery for peptic ulcer disease indicated?

A
  • uncontrolled bleeding
  • performation
  • obstruction
  • intractable disease
  • suspected malignancy
21
Q

How is esophageal variceal bleed treated?

A
  • Hemodynamic resuscitation
  • FFP for coagulopathy, platelet if indicated
  • ABX prophylaxix (3rd gen cephalosporin)
  • Somatostatin and octreotide
  • Endoscopic therapy (banding)
  • Vit K for cirrhotic pts
  • Lactulose for encephlopathy
  • Balloon tube tamponade used if cannot be controlled by meds or endoscopic techniques
22
Q

How is esophageal variceal rebleed prevented?

A
  • BB (nadolol, propranolol) plus banding
  • TIPS
  • Liver transplant
23
Q

what are some etiologies of lower GI bleed?

A
  • < 50: infectious colitis, anorectal disease, IBD
  • > 50: diverticulosis, angioectasias, malignancy, or ischemia
  • Diverticulosis: most common cause of major LGIB (acute, painles, large volume, maroon or bright red hematochezia
  • Angioectasias (common in pts >70 with CKD
  • neoplasms
  • IBD
  • anorectal disease
  • Ischemic colitis: crampy abd pain followed by rectal bleeding and no more abd pain, self limited
24
Q

most common cause of intestinal obstruction

A

peritoneal adhesions. can occur at anytime after a laparotomy. intra-abd infection, ischemia, and peritonitis are at increased risk

25
Q

How does intestinal obstruction present/

A
  • colicky abd pain, nausea, vomiting (including feculent vomit), abd distention, and absence of flatus or stooling
  • CT may show air-fluid levels, dilated bowels and decompressed bowel distal to the site of obstruciton
26
Q

how is intestinal obstruction treated?

A
  • NG tube decompression and fluid resuscitation

- urgent laparotomy for lysis of adhesions must be performed before bowel ischemia develops

27
Q

what are some complications of hernias?

A
  • Irreducible (hernia contents cannot be manipuated back into abd cavity
  • Incarcerated (contents of sac are literallly inprisoned in the sac of hernia)
  • Obstruction ( the loop of bowel become non functioning with normal blood supply)
  • Strangulated (cut off the blood supply to the content sac )
28
Q

Toxic megacolon is a comlication of

A

IBD and C diff colitis. risk of performation

29
Q

How would a pt with spontaneous bacterial peritonitis present?

A
  • fever, abd pain, peritoneal signs, ascitic fluid netrophil count >250, change in mental status
30
Q

Common bugs associated with spontaneous bacterial peritonitis

A

Gram (-): E coli, Klebsiella

Gram (+): strep pneumo, strep viridans, enterococcus

31
Q

what drugs can help prevent spontaneous bacterial peritonitis?

A
  • once daily nofloxacin or ciprofloxacin or TMP-SMX
32
Q

How is Spontaneous bacterial peritonitis treated?

A

3rd gen cephalosproin or combo beta lactam/lactamase agents

  • IV albumin to increase effective arterial circulating volume and renal perfusion helps decrease kidney injury (hepatorenal syndrome) and mortality
  • Stop BB, it increases risk of hepatorenal syndrome
33
Q

What are secondary cause of bacterial peritonitis?

A
  • treatment with broad spectrum enteric coverage for aerobic and anaerobic flora (3rd gen cephalosproin and metronidazole)
34
Q

major sign of hallow organ perforation

A
  • pneumoperitoneum

- free air on xray or CT

35
Q

what is the most common abd surgical emergency?

A

appendicitis

36
Q

common cause of appendicitis

A

obstruction of appendix by a fecalith, inflammation, foreign body, or neoplasm –> increase intraluminal pressure, venous congestion, infection, thrombosis of intramural vessels –> gangrenous and perforates within 36hrs if untreated

37
Q

what is familial mediterranean fever?

A

autosomal recessive disorder of unkown pathogenesis, seen in younger than 20 of mediterranean ancestry, lacks protease in serosal fluids that normally inactivates IL8 and complement factor 5A

38
Q

how do familial mediterranean fever patients present?

A
  • episodic bouts of acute peritonitis

- associated with serositis invlving joints and pleura

39
Q

what’s the treatment for familial mediterranean fever?

A
  • self limited within 24-48 hours.
  • symptoms resmeble surgical peritonitis and pts undergo unnecessary explorative laprotomy
  • Colchicine can decrease severity and attacks