Gi Emergencies Flashcards

1
Q

What is SBP

A

Most commonly seen in patients with end stage liver disease (patients with cirrhosis) Spontaneous bacterial peritonitis (SBP) is an infection of ascitic fluid that cannot be attributed to any intra-abdominal, ongoing inflammatory, or surgically correctable condition
• Ascites is a pathological collection of fluid within the peritoneal cavity •In cirrhosis it is caused by a combination of:
• Portal hypertension- Causing increased hydrostatic pressure in the veins draining the gut
• Decreased liver function resulting in less albumin production- Decreased intravascular oncotic pressure
• The result is the net movement of fluid into the peritoneal cavity

  • Symptoms of abdominal pain, fever, vomiting
  • Commonly symptoms are mild
  • Diagnosed by aspirating ascitic fluid- neutrophil count >250 cells/mm³
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2
Q

What is secondary peritonitis

A

Secondary (surgical) peritonitis is a result of an inflammatory process in the peritoneal cavity secondary to inflammation, perforation, or gangrene of an intra-abdominal or retroperitoneal structure
• Remember the peritoneal cavity is normally a sterile environment
•If a viscera perforates then the contents will enter the peritoneal cavity
•Common causes of secondary bacterial peritonitis include:
• Peptic ulcer disease (perforated)
• Appendicitis (perforated)
• Diverticulitis (perforated)
• Post surgery

  • Non bacterial causes
  • Tubal pregnancy that bleeds (the peritoneal cavity is not enclosed in females)
  • Ovarian cyst
  • Blood is highly irritant to the peritoneal cavity
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3
Q

What are teh symptoms of peritonitis

A

Abdominal pain is the most common symptom
• This may come on gradually or acutely
•Diffuse abdominal pain is common in perforated viscera
•Patients often lie very still as any movement makes the pain worse
• Often have knees flexed
• Shallow breathing
•Treatment approaches

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4
Q

Wha are the treatment approaches for peritonitis

A
Treatment approaches
•Control the infectious source
• Surgery •Eliminate bacteria and toxins
• Antibacterial therapy •Maintain organ system function
• Intensive care
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5
Q

What is bowel obstruction and wat are common causes

A

Bowel obstruction is a mechanical or functional problem that inhibits the normal movement of gut contents
• This can affect the large and small intestine
•All ages can be affected

  • Common causes in children include:
  • Intussusception • Intestinal atresia
  • Common causes in adults include:
  • Adhesions • Incarcerated hernias
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6
Q

What is intussusception and what is thr treatment

A

Intussusception is when one part of the gut tube telescopes into an adjacent section
• The cause is not well known
• Potential motility issues
• ‘Lead point’ (a mass that precipitates the telescoping action)
- Meckel’s diverticulum
- Enlarged lymph node
•The intussusception can extend quite far (even prolapse out of rectum)
•As soon as the lymphatic and venous drainage is impaired you get oedema
• Enough oedema can impede arterial supply (infarction)
•Classically you get abdominal pain, vomiting and haematochezia
•Treatment
• Air enema
• Surgery

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7
Q

What are the Cuba’s of small bowel obstction

A

Nausea and vomiting (bilious) are most common symptom (early) • Abdominal distension •Absolute constipation (late) •Caused by:
• Intra-abdominal adhesions (abnormal fibrous bands between organs or tissues or both in the abdominal cavity that are normally separated)
• Arise after more than 50% of abdominal surgeries
• Greater omentum involved in 80%, bowel in 50% • Damage to mesothelium (direct trauma, post operative infection)
• Capillary bleeding leads to exudation of fibrinogen • Other consequences of adhesions
• Abdominal pain, secondary infertility

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8
Q

How can hernias cause small bowell obstructing

A
  • Hernias can narrow lumen enough to cause obstruction
  • Incarcerated groin hernias most common
  • Inflammatory bowel disease
  • Crohn’s
  • Repeated episodes of inflammation/healing causes narrowing
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9
Q

Descrbe the small bowell obstruction diagnosis

A

Diagnosis
• History- abdominal pain is crampy, intermittent
• Physical examination- abdominal distension, increased/absent bowel sounds, presence of hernia
• Imaging-

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10
Q

Wha are common causes and symptoms of large bowel obstruction

A
Typically affects older generation 
• Common causes include:
• Colon cancer (60% of mechanical obstructions) 
• Diverticular disease (20%) 
• Volvulus- Sigmoid, Caecal (5%)
  • Symptoms often appear gradually if caused by cancer but are abrupt with volvulus
  • Change in bowel habit (cancer)
  • Abdominal distension
  • Crampy abdominal pain
  • Nausea/vomiting (later)
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11
Q

What is volvulus

A

Derived from Latin ‘to twist’
• Part of the colon twists around its mesentery
•Most common in sigmoid colon (60%) and caecum (but can technically occur anywhere)
•Results in obstruction
•Can result from overloaded sigmoid colon (constipation)
- Extra mass predisposes elongates the sigmoid (relatively smaller mesenteric attachment)
- High fibre diets can also lead to sigmoid overload and twisting
•Caecal volvulus results in small and large bowel obstruction

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12
Q

Omapre small vs large bowel obstruction

A

Ss

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13
Q

Compare small and large bowel obstruction imaging

A

Ss

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14
Q

What is acute mesenteric ischaemia

A

Symptomatic reduction in blood supply to the GI tract
• More common in females (75%) and if you have a history of peripheral vascular disease
•Acute occlusion (70% of cases)
- Arterial embolism in SMA (50%)
•Non occlusive mesenteric ischaemia (20%)
- Low cardiac output
•Mesenteric venous thrombosis (5-10%)
- Systemic coagulopathy, malignancy

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15
Q

Describe teh diagnosis and investigations of acute mesenteric ischaemia

A

Most cases are in more elderly patients with a cardiovascular risk factors
• Can be difficult to diagnose because the symptoms can be fairly non-specific
•Abdominal pain (if present) is disproportionate to the clinical findings
- Classically pain comes on 30 minutes after eating (and last 4 hours)
•Nausea and vomiting are often present
•Pain can often left sided because the blood supply to the splenic flexure is most fragile

  • Investigations
  • Blood tests
  • Metabolic acidosis/increased lactate levels
  • Erect chest x-ray (to check for perforation)
  • CT angiography is used (sensitivity is >90%) –intravenous contrast
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16
Q

What are the treatments for acute mesenteric ischaemia

A

Treatment • Surgery- resection of ischaemic bowel
• bypass graft •Thrombolysis/angioplasty
•Mortality is high (arterial thrombosis up to 70% mortality)
• Often older patients with comorbidities

17
Q

Describe oesophageal varices

A

Oesophageal varices
• This is an example of a porto-systemic anastomosis
• 12-14% of acute upper GI bleeding
• In case of oesophageal varices
• Portal drainage- Oesophageal veins drain into left gastric vein, drains into portal vein
• Systemic drainage- Oesophageal veins drain into azygous vein, drains into superior vena cava

18
Q

What is band ligation

A

-

19
Q

What are treatments of oesophageal varices

A

If bleeding is not controlled by the ‘banding’
• TIPS (Transjugular intrahepatic portosystemic shunt)
- An expandable metal is placed within the liver
- Bridges the portal vein to an hepatic vein
• Decompresses the portal vein pressure
• Reduction in variceal pressure
• Reduction in ascites

  • Drug treatment
  • Terlipressin
  • Reduces portal venous pressure
20
Q

What are AAAs

A

Abdominal aortic aneurysm (AAA) is a permanent pathological dilation of the aorta with a diameter >1.5 times the expected anteroposterior (AP) diameter of that segment, given the patient’s sex and body size. The most commonly adopted threshold is a diameter of 3 cm or more. More than 90% of aneurysms originate below the renal arteries

Usually due to the degeneration of the media layer of the arterial wall
• Media- smooth muscle cells with elastin & collagen
- AAAs form due to degradation of elastin and collagen
• Lumen gradually starts to dilate
Most AAAs are infrarenal (>90%)

Risk factors
• Male
• Inherited risk
• Increasing age
• Smoking
21
Q

Whar are the symptoms of aaa

A

Normally asymptomatic until acute expansion or rupture
• Can cause symptoms by compressing other nearby structures
• Stomach, bladder, vertebra
- Nausea, urinary frequency and back pain
•Usual presentation of rupture
• Abdominal pain (+/-flank and groin pain)
• Back pain
• Pulsatile abdominal mass
• Transient hypotension
- Syncope
- Retroperitoneum can temporarily tamponade the bleed
• Sudden cardiovascular collapse (65% of ruptured AAAs die before hospital)

22
Q

Desrube the diagnosis of aaa

A

Physical examination
• Presence of a pulsatile abdominal mass (less than 50% of cases)

Ultrasonography
• Non invasive and in the right hands very sensitive and specific
• Can also detect free peritoneal blood

Computed Tomography (CT)
• Can detect a lot of surrounding anatomy that may be relevant
• Planning for elective surgery

Plain x-rays
• If aneurysm has calcified then can be seen on plain x-rays

23
Q

What are non surgical treatment of aaa

A

Non surgical
• Smoking cessation
• Hypertension control
•Surveillance of AAA
• Less than 5.5cm (most grew slowly enough to not need treatment)
• More than 5.5 cm- refer to vascular surgeons

24
Q

What are surgical treatment of aaa

A

Surgery •Endovascular repair- relining the aorta using an endograft (an exoskeleton of metallic stents over a fabric lining)
• Inserted through the femoral artery (seals below renal arteries and above common iliacs)

Open surgical repair
• Clamp aorta
•Open the aneurysm (remove thrombus and debris)
•Suture in a synthetic graft to replace diseased segment