GI embryology Flashcards

1
Q

which germ layers are the GI tract derived from

A

endoderm, visceral mesoderm, neural crest

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2
Q

what does endoderm form in GI tract

A

epithelium of mucosa

associated ducts and glands

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3
Q

what does visceral mesoderm form in GI tract

A
lamina propria
muscalris mucosa
muscalris externa 
submucosa connective tissue 
external connective tissue
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4
Q

what does the neural crest form in GI tract

A

ENS
Myenteric plexus
Aucherbach’s plexus

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5
Q

when is the myenteric plexus visible

A

week 8

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6
Q

when is the aucherbach’s plexus visible

A

week 12

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7
Q

what are mesenteries of the gut derived from

A

mesoderm

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8
Q

what are ventral mesenteries derived from

A

remenants of septum transversum

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9
Q

what are the dorsal mesenteries derived from

A

connection between visceral and somatic part of lateral plate mesoderm

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10
Q

what are the ventral mesenteries

A

falciform ligament

lesser omentum

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11
Q

what are the dorsal mesenteries

A

dorsal mesogastrium
dorsal mesoduodenum
mesentery proper
dorsal mesocolon

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12
Q

which structures are retroperitoneal

A
thoracic oesophagus 
pancreas
duodenum
ascending colon
descending colon 
rectum 
anus
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13
Q

when is the oesophagus distinguishable

A

end of week 4

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14
Q

when does the circular muscle of the oesophagus develop

A

week 5

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15
Q

when is the spleen present

A

week 5

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16
Q

what is the spleen derived from

A

dorsal mesentery

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17
Q

when does the spleen become a lymphatic organ

A

week 15-18

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18
Q

what is the spleen before it is an lymphatic organ

A

haematopoietic

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19
Q

what is the liver and gallbladder an outgrowth of

A

duodenum

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20
Q

the endoderm males up what part of the liver and gallbladder

A

liver cells and lining of the biliary tree

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21
Q

the septum transverse makes up what part of the liver and gallbladder

A

Hematopoietic cells
Kupffer cells
connective tissue

22
Q

during development what is the main site of RBC production

A

liver

23
Q

what does the pancreas start as two outgrowths from

A

duodenum

24
Q

which pancreatic bud is larger

A

dorsal

25
Q

which pancreatic bud grows at the same point as the liver bud

A

ventral

26
Q

what duct migrates with the ventral bud to the dorsal bud

A

common bile duct

27
Q

what part of the pancreas does the ventral bud form

A

uncinate process

28
Q

what part of the pancreas does the dorsal bud form

A

upper part
body
tail

29
Q

what is a minor duodenal papilla

A

when the dorsal pancreatic bud keeps its communication into duodenum

30
Q

what is an annular pancreas

A

pair of ventral buds develop
one moves posterior
one moves anterior
surrounds duodenum putting pressure on it

31
Q

which artery supplies the foregut

A

celiac artery

32
Q

which artery supplies the midgut

A

superior mesenteric artery

33
Q

which artery supplies the hindgut

A

inferior mesenteric artery

34
Q

when is the swelling of the forgut (stomach) distinguishable

A

end of week 4

35
Q

when the stomach rotates 90 degrees along its longitudinal axis where do the vagus nerves lie

A

left vagus nerve becomes anterior

right vagus nerve becomes posterior

36
Q

which mesentery grows faster

A

dorsal

37
Q

what does the midgut communicate with for most of its development

A

yolk sac

38
Q

what does the primary intestinal loop rotate around

A

superior mesenteric artery

39
Q

where does the caecal bud form

A

caudal limb of primary intestinal loop

40
Q

when does re entry to body cavity occur

A

week 10

41
Q

when is the vitelline duct to the yolk sac lost

A

after re-entry

42
Q

what is a Meckel diverticulum

A

vitelline duct doesn’t regress after re entry and there is an anchor point for small intestine

43
Q

what does a vitelline cyst cause

A

anchoring point for small intestine

44
Q

what is a vitelline fistula

A

when vitelline duct remains open at umbilicus

45
Q

what does non rotation of small intestine cause

A

displaced midgut structures

46
Q

what does malrotation of midgut on re entry cause

A

duodenum crosses transverse colon anteriorly not posteriorly

47
Q

what divides the cloaca into anterior and posterior segments

A

urorectal septum

48
Q

what does the anterior segment of cloaca form

A

primitive urogenital sinus

49
Q

what does the posterior segment of cloaca form

A

anorectal canal

50
Q

what is a urorectula fistula

A

failure of complete separation of cloaca in males

51
Q

what is a rectoperineal fistula

A

communication between rectum and bladder