GI Drugs Flashcards
Bismuth salicylate
Class as trade name
Antidiarrheal, Pepto-Bismol
Imodium Multi-Symptom Relief
Class and what two drugs?
Antidiarrheal, loperamide + simethicone
Lomotil
Class and what two drugs? What do you need to know when giving a new Rx?
Antidiarrheal, diphenoxylate + atropine
Controlled substance!
Loperamide
Class and trade name?
Antidiarrheal, Imodium
Motofen
Class and what two drugs?
Antidiarrheal; difenoxin + atropine
Opium tincture
Class?
Antidiarrheal
Dolasteron
Class and MOA?
Antiemetic; 5-HT3 antagonist
Granisteron
Class and MOA?
Antiemetic; 5-HT3 antagonist
Odansteron
Class, MOA, trade and ADRs?
Antiemetic; 5-HT3 antagonist.
Zofran, ADRs include SJS, TEN, QT prolongation, HA/N/D/V
Palonosteron
Class?
Antiemetic; 5-HT3 antagonist
Aprepitant
Class?
Antiemtetic (Other)
Diclegis
Class and what two drugs?
Antiemtetic (Other); doxylamine + pyridoxine
Dimenhydrinate
Class and trade?
hint: think Modest Mouse….
Antiemtetic (Other); Dramamine
Domperidone
Class?
Antiemtetic (Other)
Doxylamine
Class?
Antiemtetic (Other)
Dronabinol
Class, trade and what do you need to know when giving a new Rx?
Antiemtetic (Other); Marinol, controlled substance, this is a cannabis derivative!
Droperidol
Class?
Antiemtetic (Other)
Metoclopramide
Class and trade?
Antiemtetic (Other); Reglan
Nabilone
Class?
Antiemtetic (Other)
Phosporated Carbohydrates
Class and trade?
Antiemtetic (Other); Emetrol
Prochlorperazine
Class and trade?
Antiemtetic (Other); Compazine
Promethazine
Class and trade?
Antiemtetic (Other); Phenegran
Scopolamine
Class?
Antiemtetic (Other)
Trimethobenzamide
Class?
Antiemtetic (Other)
Alka-Seltzer
Class and what three components?
Antiulcer- Antacid; acetylsalicylic acid + citrate + bicarbonate
Aluminum Hydroxide
Class and trade?
Antiulcer- Antacid; Alternagel
Gaviscon
Class and what two components?
Antiulcer- Antacid; aluminum hydroxide + magnesium carbonate
Maalox
Class and what two components?
Antiulcer- Antacid; aluminum hydroxide + magnesium carbonate
Magaldrate
Class?
Antiulcer- Antacid
Mylanta
Class and what three components?
Antiulcer- Antacid; aluminum hydroxide + magnesium carbonate + simethicone
Rolaids
Class and what two components?
Antiulcer- Antacid; calcium carbonate + magnesium hydroxide
Cimetidine
Class, MOA, trade and what do you need to worry about?
Antiulcer- H2 antagonists; Tagament and COOMADIN
Famotidine
Class, MOA and trade?
Antiulcer- H2 antagonists; Pepcid
Nizatidine
Class and MOA?
Antiulcer- H2 antagonists
Pepcid complete
Class, MOA and what three components?
Antiulcer- H2 antagonists; famotidine + calcium carbonate + magnesium hydroxide
Ranitidine
Class, MOA and trade?
Antiulcer- H2 antagonists; Zantac
Helidac
Class and what three components?
Antiulcer- Helicobacter pylori treatment; bismuth subsalicylate + metronidazole + tertracycline
Prevpac
Class and what three components?
Antiulcer- Helicobacter pylori treatment; lansoprazole + amoxicillin + clarithromycin
Pylera
Class and what three components?
Antiulcer- Helicobacter pylori treatment; bismuth subcitrate potassium + metronidazole + tetracycline
Esomeprazole
Class, MOA and trade?
Antiulcer- PPI; Nexium
Heliobacter Pylori Therapy
Triple therapy PO 10-14 days
Clarithromycin 500mg BID + Amoxicillin 1g BID (or metronidazole 500mg BID) + PPI
Lansoprazole
Class, MOA and trade?
Antiulcer- PPI; Prevacid
Omeprazole
Class, MOA, trade and some indications?
Antiulcer- PPI; Prilosec. GERD, duodenal ulcer, erosive esophagitis and heartburn
Pantoprazole
Class, MOA and trade?
Antiulcer- PPI; Protonix
Raberprazole
Class, MOA and trade?
Antiulcer- PPI; AcipHex
Zegerid
Class, MOA and what two components?
Antiulcer- PPI; omeprazole + bicarbonate
Dicyclomine
Class and trade?
Antiulcer- other; Bentyl
Donnatal
Class and what four components?
Antiulcer- other; phenobarbital + hyoscyamine + atropine + scopolamine
GI Cocktail
Indication, trade and what components?
Acute GI upset; Maalox + Mylanta + lidocaine + Donnatal
Hyoscine
Class and trade?
Antiulcer- other; Buscopan
Hyoscyamine
Class and trade?
Antiulcer- other; Anaspaz
Misoprosotol
Class, trade and special indication?
Antiulcer- other; PGE1/Cytotec. Cervical ripening…..the slipn n’ slide
Propantheline
Class and trade?
Antiulcer- other; Pro-banthine
Simethicone
Class and trade?
Antiulcer- other; Mylicon, Gas-X
Sucralfate
Class and trade?
Antiulcer- other; Carafate
Methylcellulose
Class and trade?
Laxatives- bulk forming; Cirtucel
Polycarbophil
Class and trade?
Laxatives- bulk forming; Fibercon
Psyllium
Class and trade?
Laxatives- bulk forming; Metamucil
Glycerin
Class and trade?
Laxatives- osmotic; Fleet
Lactulose
Class and trade?
Laxatives- osmotic; Enulose
Magnesum citrate
Class?
Laxatives- osmotic
Mangesium hydroxide
Class and trade?
Laxatives- osmotic; Milk of Magnesia
Polyethylene glycol
Class and trade?
Laxatives- osmotic; Miralax/Glycolax
Polyethylene glycol w/electrolytes
Class and indication?
Laxatives- osmotic; bowel prep
Prepopik
Class?
Laxatives- osmotic
Sodium phosphate
Class, trade and indication?
Laxatives- osmotic; Fleet enema, prep prior to colonoscopy
Sorbitol
Class?
Laxatives- osmotic
Suprep
Class and components?
Laxatives- osmotic; sodium sulfate + postassium sulfate + magesium sulfate
Bisacodyl
Class and trade?
Laxatives- stimulant; Correctol/Ducolax
Cascara
Class?
Laxatives- stimulant
Castor Oil
Class?
Laxatives- stimulant
Senna
Class and trade?
Laxatives- stimulant; Senokot
Docusate
Class and trade?
Laxatives- stool softener; Colace
Lubiprostone
Class and trade?
Laxatives- other; Amitiza
Mineral oil
Class and trade?
Laxatives- other; Fleet Mineral Oil
Peri-Colace
Class and what two components?
Laxatives- other; docusate + semosides
Senokot-S
Class and what two components?
Laxatives- other; senna + docusate
Balsalazide
Indication?
Ulcerative Colitis
Mesalamine
Indication and trade?
Ulcerative Colitis; 5-Aspirin, Apriso
Olsalazine
Indication and trade?
Ulcerative Colitis; Dipentum
Sulfasalazine
Indication and trade?
Ulcerative Colitis; Azulfidine
Alosteron
Indication?
Diarrhea predominant IBS in women who failed conventional therapy
Alpha-Galatosidase
Trade?
Beano
Alvimopan
Trade and indication?
Entereg; short term for bowel resection surgery w/primary anastomosis, speeds up healing
Budesonide
Trade and indication?
Entocort; Crohn’s and Ulcerative Colitis
Certolizumab
Trade and indications?
Cimzia; Crohn’s and RA
Chlordiazepoxide-Clidinium Trade, class and indications?
Librax; benzodiazepine. For PUD and IBS
Crofelemer
Trade and indication?
Fulyzaql non infectious AIDS diarrhea
Glycopyrrolate
Trade and indications?
Robinul; PUD and chronic drooling in children
Lactase
Trade?
Lactaid
Linaclotide
Trade and indications?
Linzess; IBS and chronic idiopathic constipation
Lorcaserin
Trade and indications?
Belviq; obesity or overweight with comorbidities
Methylnaltrexone
Trade and indication?
Relistor; opioid induced constipation
Neomycin Oral
Indication?
Hepatic encephalopathy
Octreotide
Trade and indication?
Sandostatin; Variceal bleeding and AIDS diarrhea
Orilstat
Trade and indication?
Alli/Zenical; weight loss
Pancreatin
Trade and indications?
Creon; contains digestive enzymes and is reported to helped with food allergies and Celiac
Pancrelipase
Trade and indications?
Creon; contains digestive enzymes and is reported to helped with food allergies and Celiac
Pinaverium
Trade and indications?
Dicetel; helps restore bowel function
Qsymia
Alternate name and indication?
Phentermine and topiramate; obesity or overweight with comorbidities
Rectiv
Alternate name and indication?
Nitroglycerin; painful chronic anal fissures
Secretin
Trade and indication?
SecreFlo; peptide hormone that regulates water balance
Teduglutide
Trade and indication?
Gattex; Short bowel syndrome patients recieving IV TPN
Ursodiol
Trade and indications?
Actigall; gallstone solution, gallstone prevention associated with rapid weight loss and primary billiary cirrhosis