GI drugs Flashcards

1
Q

compazine moa?

A

antiemetic

dopamine receptor antagonist

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2
Q

compazine uses?

A

motion sickness

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3
Q

compazine adverse effects (AE)?

A

dystonia, tardive dyskinesia, depression, hypotension

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4
Q

zofran moa?

A

antiemetic

serotonin receptor antagonist

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5
Q

zofran uses?

A

most widely used for chemotherapy induced emesis

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6
Q

zofran ae?

A

well tolerated
mild HA
constipation
dizziness

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7
Q

reglan moa?

A

antiemetic

dopamine receptor antagonist

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8
Q

reglan uses?

A

modest antiemetic
speeds gastric emptying
increases tone in lower esophageal sphincter

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9
Q

reglan ae?

A

CROSSES BLOOD BRAIN BARRIER!!

BLACK BOX WARNING: tardive dyskinesia (irreversible)

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10
Q

marinol/THC moa?

A

antiemetic

cannabinoid (actual moa unk)

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11
Q

marinol/THC uses?

A

stimulates appetite, reduces nausea in chemotherapy, AIDs, anorexia pts

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12
Q

marinol/THC ae?

A

vertigo, xerostomia, hypotension, dysphoria

use with caution in pts with subs. abuse hx

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13
Q

activated charcoal moa?

A

binding the toxin

absorbs ingested poisons w/in gut lumen, allowing the complex to be evacuated w/ stool

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14
Q

activated charcoal uses?

A

> 90% of toxin is absorbed when ratio of charcoal to toxin is 10:1

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15
Q

activated charcoal ae?

A

contraindications:
bowel obst/perforation
depressed LOC
not for acidic or alkaline corrosives

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