GI Cancer

Question 1

Intestinal type Gastric cancer

Answer 1

exophytic/polypoid mass

Question 2

Diffuse type Gastric cancer

Answer 2

expands/infiltrates stomach wall

signet rings on biopsy
lintis plastica

Question 3

Anaemia, mass in RIF, cachexia (wasting)

Answer 3

cancer in ascending colon, RHS

Question 4

rectal bleeding, change in bowel, colicky pain

Answer 4

cancer in LHS

Question 5

HNPCC

Answer 5

right sided
mucinous
cancer aged under 50
autosomal dominant, defect in DNA mismatch repair
no polyps

Question 6

FAP

Answer 6

desmoid tumour
thyroid carcinoma
throughout colon
autosomal dominant, forms polyps
gardener's syndrome

Question 7

Screening for colorectal cancer

Answer 7

Faecal occult blood test

Question 8

Investigation for colorectal cancer

Answer 8

colonoscopy, sigmoidoscopy if under 45 + biopsy

then do barium enema, CT to stage it

XRAY - apple core sign

Question 9

Tumour marker for colorectal

Answer 9

CEA

Question 10

Gastrinoma

Answer 10

G cell
associated with zollinger ellison
inc acid, peptic ulcer

Question 11

Pancreatic cancer

Answer 11

painless jaundice
back pain sometimes
steatorrhea, malaena
charred meat, diabetes, smoking, obesity

Question 12

Oral cancer

Answer 12

most common on ventral surface, floor of mouth, lateral tongue