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GI Pathogens > GI Bacteria: Colonization (+/- toxin) mediated > Flashcards

GI Bacteria: Colonization (+/- toxin) mediated Flashcards

1
Q

Epi of Salmonella (non typhoidal)

A
  • Contaminated animal products e.g. meat/eggs
  • Reptiles
  • 10% food borne illness USA
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2
Q

Epi of Salmonella (typhoidal)

A

human-human evolution; human feces/carriers

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3
Q

Epi of Shigella

A

Human-human fecal oral (4 Fs); High infectivity; daycare centers

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4
Q

Yersinia Epi (3)

A

Animal hosts (rodents, pets, etc; contaminated pork/beef; anemia and infants high risk

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5
Q

contaminated animal product (POULTRY, milk)

10-15% food poisoning in USA

A

Campy Epi

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6
Q

H Pylori EPi

A

person to person saliva

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7
Q

EHEC

A

Ground beef, cattle refuse: water, radishes, spinach, apple juice

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8
Q

uncooked foods (salad fruits); childhood diarrhea developing countries

A

ETEC

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9
Q

B. Cereus

A

Fried rice is risk for emetic form. Cream milk sauce is risk for diarrheal form.

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10
Q

Listeria

A

cheeses, milk, veggies. Pregnant mothers, immunocompromised, neonates

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11
Q

Vibrio

A

contaminated water/seafood/fish

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12
Q

ddx for acute bloody diarrhea in bacterial setting

A 
EHEC (starts watery)
EIEC
Campy
Shigella
Salmonella (non-typhoidal)
Yersinia Entercolitica
C. diff (possibly)
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13
Q

List bacteria that are invasive and could result in bloody stools

A 
Salmonella
Campy
Shigella
Yersinia
EIEC (similar but milder bloody diarrhea than shigellosis)
Vibrio (not bloody)
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14
Q

invades terminal ileum and stops in lamina propria

A

non typhoidal salmonella

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15
Q

invades intestinal epithelium and causes ulceration/bleeding of mucosa

A

campy

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16
Q

shigella entry

A

invades m cells and lyses phagosome

17
Q

sort salmonella (both forms), shigella, vibrio (all forms), e coli (EPEC, EHEC, EAEC, DAEC, EIEC) as intracellular or extracellular

A

all intracellular except for vibrio cholerae and EPEC, EHEC, ETEC, EAEC, DAEC. Vib Vuln is either or.

18
Q

travelers diarrhea

A

ETEC or EAEC

19
Q

infants can get this form of E Coli

A

EPEC

20
Q

describe clinical presentation of typhoidal salmonella

A

malaise, fever, headache, myalgia, ROSE SPOT, constipation

21
Q

describe clinical presentation of EPEC

A

copious watery mucoid infant diarrhea everywhere

22
Q

describe clinical presentation of ETEC

A

travelers diarrhea (watery, profuse). Also, infant diarrhea in developing countries.

23
Q

describe clinical presentation of shigella

A

abd cramps, TENESMUS, frequent scant bloody stools with pus, fever. Can be just watery diarrhea, OR start out watery and progress.

24
Q

describe clinical presentation of yersinia

A

bloody diarrhea, mesenteric lymphadenitis

25
Q

describe clinical presentation of campy

A

diarrhea (bloody), fever, abd pain. Can have GBS or Reiters too.

26
Q

describe clinical presentation of Salmonella (both types)

A

Salmonella non typhoidal: NV, abd cramping, non bloody diarrhea x3-4 days, +/- bloody diarrhea, fever, septicemia, meningitis, osteomyelitis;

Salmonella typhoidal: fever malaise constipation myalgia, headache, ROSE SPOTS, +/- GI hemmorhage, perf, metastatic spread, colonize GB

27
Q

name 8 causes of acute non inflammatory diarrhea (bacteria +virus +protozoa)

A

virus: rotavirus, norovirus
protozoa: giardia, cryptosporidium
Bacteria: staph aureus(?), vibrio cholerae, ETEC, bacillus cereus

28
Q

name 9 cases of acute inflammatory diarrhea (bacteria +virus+protozoa)

A

virus: cmv
protozoa: entamoeba histolytica, schistosomiasis
bacteria: campy, salmonella, shigella, ehec, c. diff, yersinia

29
Q

is small bowel mostly the target for inflammatory or non inflammatory diarrhea?

A

non inflammatory (exception: salmonella more often in small bowel)

30
Q

which conditions require abx therapy (5) (bacteria and protozoa)

A

shigella, salmonella, c diff, giardia, e histolytica

31
Q

what can you use for inflammatory diarrhea in terms of antimotility?

A

bismuth subsalicylate

32
Q

name infectious and inflammatory (but still infectious) causes of chronic diarrhea

A

v cholera, ETEC, whipple disease, c. diff, yersinia, cmv, e histolytica

GI Pathogens (5 decks)

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