GI Agents Flashcards
sucralfate
Pharmacologic Category: Antiulcer Protectant
Brand Name: Carafate
Indication: Duodenal Ulcer
Pearls: Administer on an empty stomach
famotidine
Pharmacologic Category: Histamine H2 antagonist (H2RA)
Brand Name: Pepcid
Indication: GERD
Pearls: Take 10-60 min minutes before meals causing heartburn
pantoprazole
Pharmacologic Category: Proton Pump Inhibitor (PPI)
Brand Name: Protonix
Indication: GERD
Pearls: Take 30-60 minutes before meals (formulation specific); Do NOT crush, cut, or chew tablets/capsules
omeprazole
Pharmacologic Category: Proton Pump Inhibitor (PPI)
Brand Name: Prilosec
Indication: GERD
Pearls: Take 30-60 minutes before meals (formulation specific); Do NOT crush, cut, or chew tablets/capsules
esomeprazole
Pharmacologic Category: Proton Pump Inhibitor (PPI)
Brand Name: Nexium
Indication: GERD
Pearls: Take 30-60 minutes before meals (formulation specific); Do NOT crush, cut, or chew tablets/capsules
dexlansoprazole
Pharmacologic Category: Proton Pump Inhibitor (PPI)
Brand Name: Dexilant
Indication: GERD
Pearls: Take 30-60 minutes before meals (formulation specific); Do NOT crush, cut, or chew tablets/capsules
lansoprazole
Pharmacologic Category: Proton Pump Inhibitor (PPI)
Brand Name: Prevacid
Indication: GERD
Pearls: Take 30-60 minutes before meals (formulation specific); Do NOT crush, cut, or chew tablets/capsules
dronabinol
Pharmacologic Category: Cannabinoid
Brand Name: Marinol; Syndros
Indication: Chemotherapy-induced nausea and vomiting
Pearls: Scheduled: Marinol (C-III); Syndros (C-II)
Side Effects: euphoria, paranoia, drowsiness
metoclopramide
Pharmacologic Category: Dopamine antagonist; Prokinetic; Serotonin 5-HT4 Receptor Agonist/5-HT3 Receptor Antagonist
Brand Name: Reglan
Indication: Gastroparesis; Chemotherapy-induced nausea and vomiting
Pearls: Boxed Warning: Tardive Dyskinesia; Avoid use in patients with Parkinson Disease
promethazine
Pharmacologic Category: Histamine H1 antagonist; Phenothiazine
Brand Name: Phenergan
Indication: Nausea/vomiting
Pearls: Boxed Warning: 1) Avoid use <2 years old = respiratory depression. 2) Severe tissue injury risk from injection.
Side Effects: CNS depression, anticholinergic effects, EPS
ondansetron
Pharmacologic Category: Selective 5-HT3 Receptor Antagonist
Brand Name: Zofran
Indication: Chemotherapy-induced nausea and vomiting
Pearls: Side Effects: constipation, HA, QT prolongation
scopolamine
Pharmacologic Category: Antivertigo; Antimuscarinic
Brand Name: Transderm Scop
Indication: Motion Sickness
Pearls: Motion sickness: apply 1 patch behind the ear at least 4 hours before effect is needed; new patch every 3 days
Side Effects: dry mouth, drowsiness, dizziness, confusion, blurred vision
mesalamine
Pharmacologic Category: Anti-inflammatory; 5-Aminosalicylic Acid Derivative
Brand Name: Asacol HD; Pentasa; Apriso; Lialda; Rowasa (rectal); Canasa (rectal)
Indication: Ulcerative colitis; IBD treatment (mild disease)
Pearls: Swallow whole; do not break, chew, cut, or crush
diphenoxylate / atropine
Pharmacologic Category: Antidiarrheal / Antimuscarinic
Brand Name: Lomotil
Indication: Diarrhea
Pearls: Side Effects: CNS depression; Scheduled: C-V
dicyclomine
Pharmacologic Category: Anticholinergic
Brand Name: Bentyl
Indication: Irritable Bowel Syndrome (IBS)
Pearls: Side Effects: dizziness, dry mouth, nausea, blurred vision