GI Agents Flashcards

1
Q

sucralfate

A

Pharmacologic Category: Antiulcer Protectant
Brand Name: Carafate
Indication: Duodenal Ulcer
Pearls: Administer on an empty stomach

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2
Q

famotidine

A

Pharmacologic Category: Histamine H2 antagonist (H2RA)
Brand Name: Pepcid
Indication: GERD
Pearls: Take 10-60 min minutes before meals causing heartburn

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3
Q

pantoprazole

A

Pharmacologic Category: Proton Pump Inhibitor (PPI)
Brand Name: Protonix
Indication: GERD
Pearls: Take 30-60 minutes before meals (formulation specific); Do NOT crush, cut, or chew tablets/capsules

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4
Q

omeprazole

A

Pharmacologic Category: Proton Pump Inhibitor (PPI)
Brand Name: Prilosec
Indication: GERD
Pearls: Take 30-60 minutes before meals (formulation specific); Do NOT crush, cut, or chew tablets/capsules

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5
Q

esomeprazole

A

Pharmacologic Category: Proton Pump Inhibitor (PPI)
Brand Name: Nexium
Indication: GERD
Pearls: Take 30-60 minutes before meals (formulation specific); Do NOT crush, cut, or chew tablets/capsules

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6
Q

dexlansoprazole

A

Pharmacologic Category: Proton Pump Inhibitor (PPI)
Brand Name: Dexilant
Indication: GERD
Pearls: Take 30-60 minutes before meals (formulation specific); Do NOT crush, cut, or chew tablets/capsules

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7
Q

lansoprazole

A

Pharmacologic Category: Proton Pump Inhibitor (PPI)
Brand Name: Prevacid
Indication: GERD
Pearls: Take 30-60 minutes before meals (formulation specific); Do NOT crush, cut, or chew tablets/capsules

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8
Q

dronabinol

A

Pharmacologic Category: Cannabinoid
Brand Name: Marinol; Syndros
Indication: Chemotherapy-induced nausea and vomiting
Pearls: Scheduled: Marinol (C-III); Syndros (C-II)
Side Effects: euphoria, paranoia, drowsiness

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9
Q

metoclopramide

A

Pharmacologic Category: Dopamine antagonist; Prokinetic; Serotonin 5-HT4 Receptor Agonist/5-HT3 Receptor Antagonist
Brand Name: Reglan
Indication: Gastroparesis; Chemotherapy-induced nausea and vomiting
Pearls: Boxed Warning: Tardive Dyskinesia; Avoid use in patients with Parkinson Disease

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10
Q

promethazine

A

Pharmacologic Category: Histamine H1 antagonist; Phenothiazine
Brand Name: Phenergan
Indication: Nausea/vomiting
Pearls: Boxed Warning: 1) Avoid use <2 years old = respiratory depression. 2) Severe tissue injury risk from injection.
Side Effects: CNS depression, anticholinergic effects, EPS

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11
Q

ondansetron

A

Pharmacologic Category: Selective 5-HT3 Receptor Antagonist
Brand Name: Zofran
Indication: Chemotherapy-induced nausea and vomiting
Pearls: Side Effects: constipation, HA, QT prolongation

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12
Q

scopolamine

A

Pharmacologic Category: Antivertigo; Antimuscarinic
Brand Name: Transderm Scop
Indication: Motion Sickness
Pearls: Motion sickness: apply 1 patch behind the ear at least 4 hours before effect is needed; new patch every 3 days
Side Effects: dry mouth, drowsiness, dizziness, confusion, blurred vision

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13
Q

mesalamine

A

Pharmacologic Category: Anti-inflammatory; 5-Aminosalicylic Acid Derivative
Brand Name: Asacol HD; Pentasa; Apriso; Lialda; Rowasa (rectal); Canasa (rectal)
Indication: Ulcerative colitis; IBD treatment (mild disease)
Pearls: Swallow whole; do not break, chew, cut, or crush

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14
Q

diphenoxylate / atropine

A

Pharmacologic Category: Antidiarrheal / Antimuscarinic
Brand Name: Lomotil
Indication: Diarrhea
Pearls: Side Effects: CNS depression; Scheduled: C-V

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15
Q

dicyclomine

A

Pharmacologic Category: Anticholinergic
Brand Name: Bentyl
Indication: Irritable Bowel Syndrome (IBS)
Pearls: Side Effects: dizziness, dry mouth, nausea, blurred vision

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16
Q

lactulose

A

Pharmacologic Category: Ammonium Detoxicant; Laxative, Osmotic
Brand Name: Enulose; Constulose
Indication: Constipation; Hepatic encephalopathy
Pearls: Hepatic encephalopathy: goal of 2-3 stools/day

17
Q

polyethylene glycol and electrolyte solution

A

Pharmacologic Category: Laxative, Osmotic
Brand Name: Colyte; GoLYTELY
Indication: Bowel cleansing
Pearls: Side Effects: abdominal distention, nausea; May cause fluid and electrolyte disturbances

18
Q

polyethylene glycol 3350

A

Pharmacologic Category: Laxative, Osmotic
Brand Name: MiraLax
Indication: Constipation
Pearls: Side Effects: abdominal distention, nausea; May cause fluid and electrolyte disturbances