GI Flashcards
Unresectable pancreatic cancer factors?
Vascular encasement (SMA). Direct invasion of adjacent organs. Liver metastasis. Adenopathy. Ascites (peritoneal spread).
Paraneoplastic condition in pancreatic adenocarcinoma?
Trousseau’s sign (spontaneous venous thrombosis).
Normal size of duodenal papilla?
Less than 1.5 cm.
Perivaterian neoplasms?
Carcinoma. Polyps. Leiomyoma. (Familial polyposis syndrome and associated Gardner’s syndrome)
Two types of gastric volvulus?
Organoaxial. Mesenteroaxial.
Small bowel folds in Celiac disease and Scleroderma?
Celiac: Jejunum decreased folds, ileum increased folds. Scleroderma: Increased folds throughout. 5 folds per inch is normal.
Ileocecal valve upper limits of normal size?
3 cm, certainly abnormal if > 4 cm.
Most common cause of enlarged ileocecal valve?
Lipomatous infiltration.
Diseases that can enlarged the ileocecal valve?
Lipoma. Crohn’s disease. Lymphoma. Prolapsing ileal neoplasms.
2 conditions that can cause eccentric sacculations of the small bowel?
Crohn’s disease. Scleroderma.
What vitamin deficiency may occur with small bowel diverticula?
Vitamin B12 from bacterial overgrowth.
Causes of toxic megacolon?
Ulcerative colitis. Crohn disease. Infectious colitis (especially in AIDS). Ischemia. Pseudomembranous colitis.
Which colon segment is most commonly involved in toxic megacolon?.
Transverse colon (most non-dependent).
What causes the colonic dilation in toxic megacolon?
Transmural inflamation with destruction of ganglion cells (myenteric plexus).
3 causes of intramural tracking?
Diverticulitis. Crohn’s disease. Malignancy.
What disorders cause wide-mouth diverticula (pseudosacculations) in the colon?
Scleroderma. Crohn’s disease. Ischemia.
In what patient population does right-sided diverticulitis occur?
Young adults. Asians.
Main differential feature of diffuse esophageal spasms and presbyesophagus?
Diffuse esophageal spasm presents with chest pain. Presbyesophagus is asymptomatic.
Does emphysematous cholecystitis result in air in the biliary system outside of the gallbladder?
No, because the cystic duct is obstructed.
What tumors of the appendix can product pseudomyxoma peritonei?
Mucocele. Mucinous cystadenoma. Myoglobulosis.
What are the two categories of cecal volvulus?
Axial torsion. Bascule (folding of cecum on right colon without significant twisting).
What underlying condition do patients with emphysematous cholecystitis most likely have?
Diabetes.
What conditions can lead to superior mesenteric artery syndrome?
Rapid weight loss. Immobilization. Wearing a body cast. Decreased peristalsis. Drugs.
What’s the Bourne test?
In suspected enterovesical fistula, urine is collected, spun, and radiographed for dectection of barium.
What’s the difference between a fistula and a sinus tract?
Fistula tract connects two mucosal lined structures. Sinus tract ends blindly or in a cavity without normal mucosa.
What drug is associated with pneumatosis of the bowel?
Steroids.
What pulmonary and collagen vascular diseases can cause pneumatosis of the bowel?
Scleroderma. SLE. Dermatomyositis. Asthma. COPD. CF.
Factors that distinguish a pancreatic abscess from pseudocyst?
Abscess (forms earlier after pancreatitis, days to weeks, high HU 20-50, may contain air).
Gallstone ileus triad?
Air in biliary system. Radiopaque stone. Bowel obstruction. All 3 present probably only 30% of the time.
Causes of nodular filling defects in duodenal bulb and proximal duodenum?
Heterotopic gastric mucosa. Benign lymphoid hyperplasia. Brunner’s gland hyperplasia (large nodules).
What conditions may result in loss of haustral folds?
Most types of colitis. Laxative abuse. Scleroderma.
Most common location in stomach for a malignant ulcer?
Antrum (most common area for benign ulcers, too). Fundus ulcers, though uncommon, are more likely to be malignant.
What liver lesion exhibitis cetripetal opacification?
Hemangioma, peripheral to central enhancement over time.
Spigelian, Richter’s, and Littre’s hernias?
Spigelian: lower quadrant through semilunar line. Richter’s: only one wall of bowel involved. Littre’s: Meckel’s diverticulum hernia.
Disorder that causes thyroid and breast abnormalities, hyperkeratosis, and harmartomas of the small bowel?
Cowden disease.
Features of Cronkhite-Canada syndrome?
Weight loss. Anorexia. Alopecia. Multiple intestinal hamartomas.
Cutaneous masses and small bowel tumors?
Neurofibromatosis.
What conditions may cause focal strictures of the small bowel?
Crohn’s disease. Certain infections. Radiation therapy. Ischemia.
What neoplasms of the stomach grow exophytically?
Spindle cell tumors (GISTs, leiomyoma, leiomyosarcoma, leiomyoblastoma). Neurofibromas. Lymphomas.
Bony abnormalities in patients with adenomatous polyposis syndrome?
Osteomas. Cortical hyperostosis.
Possible extraintestinal neoplasms of FAPS?
Osteomas. Glioblastomas. Medulloblastomas. Thyroid carcinoma.
Congenital condition that may cause diffuse bowel edema?
Lymphangiectasia.
Complications of Caroli’s disease (Type V Choledochal Cyst or communicating cavernous ectasia of the bile ducts)?
Cholangitis. Fibrosis. Portal hypertension. Cholangiocarcinoma.
Most common cause of portal hypertension and varices worldwide (parasite)?
Shistosomiasis.
Unusual variant of esophageal carcinoma that spreads submucosally producing thickened folds?
Varicoid carcinoma of the esophagus.
Most common internal hernia?
Paraduodenal hernia.
A left paraduodenal hernia extends through the fossa of?
Landzert.
A right paraduodenal hernia etends through the fossa of?
Waldeyer.
Paraduodenal hernia is due to a congenital defect in the?
Transverse mesocolon.
Causes of rectal varices (not internal hemorrhoids)?
Portal hypertension. IVC obstruction. Severe abdominal adhesions.
Amyloidosis most commonly affects what part of the GI tract?
Small intestine, with valvulae thickening and mucosal granularity.
Causes of Booerrhaave’s syndrome?
Endoscopy. Seizures. Coughing. Asthma. Childbirth. Severe straining. Blunt trauma.
Pancreatic phlegmon (massive enlargement of the pancreas by inflammation tissue) complications?
Necrosis. Hemorrhage. Infection.
CREST?
Subcutaneous Calcinosis. Raynaud’s phenomenon. Esophageal dysfunction. Sclerodactyly. Telangiectasia.
Crowding of the valvulae by fibrosis (scleroderma) term?
Hidebound.
What age groups are symptomatic in annulary pancreas?
50% present as children. 50% present as adults.
Annular pancreas complications?
Duodenal obstruction. Increased susceptibility to pancreaatitis.
The substance secreted by this tumor causes an intense desmoplastic response, producing mesentery fibrosis, with tethering and kinging of small bowel?
Carcinoid tumor secreting serotonin.
Insulinoma facts?
90% benign. small less than 2 cm. Most difficult to detect on imaging.
Gastrinoma facts?
Major cause of Zollinger-Ellison syndrome. MEN-1 syndrome. 60% Malignant. Ectopic locations outside pancreas.
Glucagonoma facts?
Secrete glucagon. Produce Diabetes Mellitus. 80% Malignant.
VIPoma facts?
Secrete vasoactive intestinal peptide. WDHA (Watery Diarrhea, Hypokalemia, Achlorhydria). Variable malignancy.
Somatostatinoma facts?
Rare. Cause diarrhea.