GI

Question 1

MOA of bulk forming laxatives

Answer 1

polysaccharides that are converted into osmotically active metabolites that have the ability to draw water into the intestines –> increasing peristalsis

Question 2

bulk forming laxative drugs

Answer 2

methylcellulose, polycarbophil

Question 3

which type of laxative can also be used for diarrhea?

Answer 3

bulk forming laxatives

Question 4

bulk forming laxatives AEs

Answer 4

flatulence
sensation of abd fullness
intestinal/esophageal obstruction
fecal impaction

Question 5

surfactant laxatives MOA

Answer 5

emulsify fat and water in feces - NO EFFECT ON PERISTALSIS

Question 6

surfactant laxative drugs

Answer 6

sodium/potassium/calcium docusate (colace)

Question 7

surfactant laxatives AEs

Answer 7

bitter taste
diarrhea
throat irritation
mild, transient abd cramping

Question 8

nursing implications for bulk forming laxatives

Answer 8

mix with 240 mL and drink immediately…it congeals

DM patients need to check sugar content

Question 9

what drugs are H2 blockers

Answer 9

-tidine

Question 10

H2 blockers MOA

Answer 10

block histamine2 receptors in the parietal cells of the stomach –> reduces volume of gastric juice and its H+ concentration

Question 11

H2 blocker uses

Answer 11

gastric and duodenal ulcers
GERD
zollinger-ellison syndrome (hyper secretion of gastric acid --> peptic ulcers)
aspiration pneumonitis
heartburn, indigestion, sour stomach

Question 12

H2 blockers AEs

Answer 12

elevation in gastric pH increase risk of pneumonia

Question 13

H2 blockers patient teaching

Answer 13

take ranitidine and antacids 1 hr apart
take at bedtime
if no relief in 2 weeks –> seek medical attention

Question 14

Cimetidine has what AE

Answer 14

can cause confusion in elderly

Question 15

PPI drugs

Answer 15

-prazole