GI

Question 1

PUD: Duodenal ulcer

difference bewteen gastric

Answer 1

• epigastric pain pr dyspepsia
• hunger liek growling, gnawling, dull, aching pain
• relieved by antacid or food
• epigastric tenderness
• ages: 25-50 y.o.

Question 2

PUD: gastric ulcer

difference between duodenal

Answer 2

• epigastric pain
• pain in not relived by food
• food may precipitate symptoms
• nausea and anorexia
• ages: 55-65 y.o.

Question 3

what does cheif cells secrete?

Answer 3

• pepsin (digestive enzyme)

Question 4

what does parietal cells secrete?

Answer 4

• intrinsic factor (absorb b12)

Question 5

What is GERD?

Answer 5

• gastroesophageal reflux disease
• presence of chronic symptoms w/ or w/o mucosal damage (40%)
• occurs from abd reflux into esophagus
• increases risk for carcinoma of the esophagus

Question 6

antacids GOAL

Answer 6

• neutralize stomach acid amd reduce symptoms of heartburn

Question 7

antacid MOA and indication

Answer 7

• neutralize gastric acidilty and elevate pH of stomach
• used to relieve heartburn

Question 8

antacid SE

Answer 8

• constipation, rebound hyperacidity

Question 9

antacid consideration

Answer 9

• contraindicated in pts with CKF d/t risk of hypercalcemia

Question 10

different types of antacids

Answer 10

• OTC weak bases
  
  • Base (OH)3 or CO3 + Al, Ca, or Mg
  • Al(OH)3, CaCO3, Mg salts (hydroxide, trisilicate), Al and Mg combination
• Al(OH)3 + Mg(OH)2 = Maalox
• Al(OH)3 + Mg(OH)2 + simethicone (Mylanta)
  
  • MOA: Antacid + HCl -> salt + water
• Sodium bicarbonate: seldom used