GI Flashcards
bowel obstruction definition
Blockage of the lumen of small bowel; can perforate if necrosis present
bowel obstruction causes and risk factors
-Adhesions from prior surgery
-Strictures from Crohns, XRT or ischemia
-Hernia
-Hematoma
-Volvus/intussusception
-LBO
-Tumor, foreign body
bowel obstruction presentation and workup
Leukocytosis, dehydration
KUB: ladder-like pattern w/ air fluid levels on upright. Thickening of abd wall (thumbprinting)
CT w/ oral contrast w/ follow through
bowel obstruction treatment
Surgical consult
NGT to LIWS
IV fluids
Pain control
ABX IF: strangulation/necrosis suspected
cholecystitis definition
Inflammation of gallbladder
Cholelithiasis= stones in gallbladder
Choledocholithiasis = stones in CBD
cholecystitis causes and risk factors
-Cholelithiasis, Acalculous cholecystitis
-Bacteria
-Neoplasm
-Ischemia, torsion, strictures
-Obesity, pregnancy
4 Fs = female, fat, 40, fertile
-Female, advanced age, rapid wt loss, fad diets, high cholesterol
cholecystitis presentation
NV, bloating, gas, belching, previous episodes, RUQ pain, radiating pain to shoulder and scapula, Fever, jaundice
(+) Murphy’s sign
Mild leukocytosis, mild bili elevation, LFTs elevated (ALK PHOS)
Amylase > 500 consider pancreatitis also
cholecystitis diagnostic imaging
RUQ US = visualize stones
EKG = r/o cards issues
HIDA/PIPIDA scan = how well gallbladder is squeezing
ERCP: invasive but can place stent/remove stones and look at bili and pancr ducts
MRCP = non-invasive but non interventional
cholecystitis surgical and medical treatment
-NPO/NGT if severe NV
IV fluids
-Pain control including antispasmodics (Robinul)
-antiemetics
-ABX if infection suspected
-Sx or GI consult
Medical Tx if Sx not an option
-ursodiol for 12-24 months
-chenodeoxycholic acid
-dissolve stones w/ an ether placed directly into the gallbladder via percutaneous route
Crohns definition
Chronic inflammatory disease of bowel and digestive system that can effect any level of digestive systems
-transmural process (all layers) r/I ABD pain, perforations, abscess and strictures
Crohns presentation and workup
Labs: anemia d/t micro blood loss, B12 deficiency, inflammatory markers high, poor nutritional markers
(-) stool studies
Biopsy
Crohns management
-STOP SMOKING
-Nutritional support: maybe TPN
-Surgical consult
-ABX: flagyl, cipro, rifaximin
Steroids: IV initial then PO
-Entocort (for 1 yr)
-Pred is better but want to avoid systemic
Immunomodulating drugs: azathioprine, mercaptopurine, MTX
-Anti TNF
UC definition
Unknown etiology but characterized by intermittent bouts of inflammation of the mucosa in part of or the entire colon
UC presentation
S/s: bloody diarrhea, fever, ABD pain, wt loss, cramping
Extra colon s/s: arthralgias, ocular complications, skin disorders, liver disorders
UC workup
Labs: leukocytosis, anemia, lytes d/t diarrhea, elevated LFTs, stool Cx (-)
KUB: r/o or confirm megacolon; can help w/ disease severity by looking for feces in colon
Sigmoidoscopy/ colonoscopy w/ Bx for Dx
Can do barium enema but not as good and can’t be done during a flair
UC treatment
5-ASA: sulfasalazine, mesalamine, balsalazide
-sulfasalazine: wean on for acute flair up to 4-6 gm/day and then wean down to 2 gm/day for maintenance dosing
-supplement w/ folate
Step up to hydrocortisone
-foam enemas first
-step up to oral steroids Pred 20-30 BID taper slowly over 4-8 weeks
UC: when to hospitalize and hospital management
-NPO
-NGT if obstruction or toxic megacolon
-IV fluids
-Lytes
-TPN if wasting
-Stool sample for infection, leukocytes, occult blood
-KUB for toxic megacolon, free air and stool in colon
-SM 48-60 md/day
-ACTH 120 unit/day if not responding to SM
-cyclosporine is no response
-Surgery for removal and to cure disease
Celiacs defintion
Malabsorptive disease 2nd to intolerance of gluten that affects the small intestinal mucosa
1:100 people
Celiacs presentation and workup
s/s: stunted growth and s/s of malnutrition
IgA endomysial antibody
IgA tTG antibody tests
>90% sens and 95% specific screening
EGD w/ Bx for official Dx
Celiacs management
Remove all wheat, rye and barley products from diet
Can be refractory = very poor prognosis
PUD definition
Chronic disorder w/ lifelong tendency
Loss of enteric surface epithelium that extends deeply enough to penetrate muscularis mucosa (common duodenum and stomach)
Natural defense: mucosal barrier, good blood supply, competent sphincters
PUD risk factors
Gastric acid, pepsin, bile acids, decreased blood flow, incompetent sphincters, NSAIDS, ASA, steroids, smoking, tumors, stress, alcohol, low bicarb, H. pylori
PUD labs and results
-CBC: anemia, macrocytosis, leukocytosis if perf
-CMP: looking for liver disease, hypercalcemia, elevated BUN, dehydration
-Lipase and amylase
-Serum gastrin levels
PUD diagnostic tests
-H pylori testing: biopsy from EGD, serum test can show acute or past infection, breath test is better but cannot have ABX/antacids/pepto for 4 weeks AND no PPI for 2 weeks before test. Can do fecal test to check for cure
-CXR check for: asp PNA, effusions, eso or vicus perforation, ileus
-CT abd check for: fistula, inflammatory changes, cholecystitis, free air, liver disease
-EGD is best since it’s most accurate and can do interventions to fix condition
-UGI barium: if positive will likely still need EGD