GI - * Flashcards

1
Q

5 Fs of abdominal distention

A
Fat (obesity)
Faeces (constipation)
Foetus (pregnancy)
Flatus (GI)
Fluid (ascites)
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2
Q

Clinical features of pain

Constant/ intermittent/ severe/ loin/back, central/lower

A

Constant pain, gradual onset but progressive worsening: inflammatory cause
Intermittent pain, poorly localised: colic arising from a visceral structure
Severe pain out of proportion to clinical signs: ischaemic bowel, until proven otherwise
Loin/back pain: pancreas, renal tract, abdominal aorta i.e. retroperitoneal
Central & lower abdominal pain in children (<12yrs) is only pathological in 10-20%

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3
Q

GI causes of acute abdomen

A

Gastroduodenal: PU, gastritis, gastric volvulus, malignancy
Intestinal: appendicitis, obstruction, diverticulitis, gastroenteritis, IBD, mesenteric adenitis, strangulated hernia, intussusception (can be associated with a tumour/polyp as leading edge) , volvulus, TB
Hepatobiliary: acute/chronic cholecystitis, cholangitis, hepatitis
Pancreatic: acute/chronic pancreatitis, malignancy
Splenic: infarction, spontaneous rupture (associated with glandular fever)

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4
Q

Medical causes of acute abdomen

A

MI, DKA/HONK, lead poisoning, uraemia, sickle cell, Addison’s/phaeo, porphyria, shingles, TB, hypercalcaemia, Henoch-Schonlein Purpura, Tabes dorsalis, Bornholm disease (viral), pneumonia, Thyroid storm, polyarteritis nodosa
Porphyria, lead poisoning, Henoch-Schonlein purpura, polyarteritis nodosa, tabes dorsalis

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5
Q

Non-GI causes of acute abdomen

A

Urinary: cystitis, acute urinary retention, acute pyelonephritis, ureteric colic, hydro nephritis, pyelonephritis, polycystic kidney, tumour
Gynaecological: ruptured ectopic, torsion/ rupture of ovarian cyst, salpingitis, severe dysmenorrhoea, Mittelschmertz, endometriosis, red degeneration of a fibroid
Vascular: mesenteric angina (claudication), AAA, mesenteric embolus/venous thrombosis, ischaemic colitis, acute aortic dissection
Peritoneum: 1o/ 2o peritonitis
Abdominal wall: rectus sheath haematoma, cellulitis, strangulated hernia
Retroperitoneum: haemorrhage
Referred pain: herpes zoster, lobar pneumonia, thoracic spine disease, pleurisy, MI, pericarditis, testicular torsion

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6
Q

Acute abdomen according to position of pain

A

R-hypochondrium: gallstones, liver pain e.g. fitz hugh curtis syndrome (PID causing liver pain), referred pain
Epigastric: PUD, ulcer perforation, GORD, pancreatitis, appendicitis (early), referred heart pain
L-hypochondrium: splenic injury, tail of pancreas, pseudocyst of pancreas (cyst with no proper walls - build-up of fluid in lesser sac if pancreatic duct is blocked)
Umbilical: hernia, early appendicitis, gastroenteritis, SBO
Loin: pyelonephritis, renal calculi, diverticulitis, cancer of colon
R-iliac fossa: appendicitis, gynaecological (Mitelschmerz, PID & chlamydia, ectopic, twisted ovarian cyst), Meckel’s diverticulum, Crohn’s of the terminal ileum
Suprapubic: cystitis, pelvic pathology e.g. diverticular abscess, gynaecological problems
L-iliac fossa: diverticulitis, colon cancer, ureteric colic, back pain, gynaecological pathology

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7
Q

Acute abdomen Ix

A
U&E, FBC, amylase, LFT, CRP
ABG
urine dip
CXR / AXR
USS
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8
Q

Early treatment of acute abdomen

A

IV ABx are inappropriate without a clear diagnosis
Fluid balance, analgesia +/- antiemetics
Monitor vital signs

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9
Q

Syndromes requiring laparotomy

A

organ rupture - shock, abdo swelling, trauma Hx
Peritonitis - perforated PU/DU, diverticulum, appendix, bowel, GB
Check serum amylase - acute pancreatitis causes these signs but does not require laparotomy

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10
Q

Syndromes not requiring laparotomy

A

Local peritonitis: diverticulitis, cholecystitis, salpingitis, appendicits (surgery required), localised ileus
Colic

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11
Q

Definition of peritonitis

A

Inflammation of the peritoneum (covering of the external surfaces of all the abdominal & pelvic organs) → sepsis → septic shock → death

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12
Q

Aetiology of peritonitis

A

usually bacteral infection
Exterior cause: wound, peritoneal dialysis
Abdo viscera: perforation, anastomotic leak, bowel infarction)
septicaemia
Female genital tract

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13
Q

Spontaneous bacterial peritonitis (SBP)

A

infection of ascites fluid that cannot be attributed to any intra-abdominal cause;
one of the most freq encountered bacterial infections in patients with cirrhosis
Rx: cefotaxime or tazosin

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14
Q

Clinical Dx of SBP

A

↑ing tachycardia & pyrexia
constant abdominal pain (peritoneal inflammation) - exacerbated by any movements (e.g. coughing) & local pressure
abdo tenderness & guarding (involuntary spasm of anterior abdominal wall muscles over inflamed abdominal viscera)
rebound tenderness
localised pain during distant palpation
absence of bowel sounds in a tender, rigid abdomen
signs of shock
abdo distension (accumulation of free fluid)

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15
Q

Ix SBP

A
FBC (leucocytosis)  
Serum amylase (pancreatitis)  
Urinalysis 
Stool sample  
Ascitic tap 
USS 
Erect CXR (perforation) 
AXR (free gas)
CT (cause of peritonitis)
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16
Q

Rx SBP

A

Target underlying process: supportive therapy to prevent 2o complications
Medical: ABC, fluid+ electrolyte replacement systemic ABx, pain relief, gastric aspiration to prevent further distension
Surgical: laparotomy if cause can be removed/closed or if underlying cause unclear
Recovery. ITU

17
Q

establishing a diagnosis in acute abdomen

A

BLOODS: amylase 3x upper limit of normal is highly suggestive of acute pancreatitis
FBC (Hb, WCC), U&E (Na, K), amylase, LFTs, CRP, group & save
Cultures if considering infection as a possible diagnosis
URINE DIP: signs of infection, haematuria +-MC&S, pregnancy test for all women of reproductive age
ABG: useful in bleeding or septic patients, especially pH, pO2, PCO2 & lactate for signs of tissue hypo-perfusion
IMAGING: erect chest radiograph (free abdominal air), RUQ US (hepatobiliary), pelvic UC (tubo-ovarian disease)

18
Q

Causes of acute upper GI bleed

A
PUD
Oesophageal varices
Mallory-Weiss tear
Gastritis/ gastric erosions
Drugs (NSAIDs, aspirin, steroids, thrombolytic, anticoagulants)
Oesophagitis, duodenitis
Malignancy
19
Q

SSx of acute GI bleed

A

Anaemia
Melena
Dizziness, fainting, abdo pain, dysphagia, hypotension, tachycardia, decreased JVP and UO, cool and clammy

20
Q

RF of acute GI bleed

A

NSAIDs, steroids, alcohol, major trauma or massive burns

Risk of bleeding: anticoagulants

21
Q

Rockall and Glasgow Blatchford scores

A

GBS - predicts need for endoscopy (>6)

Rockall - morbidity

22
Q

Rx for GI bleed

A
Emergency care - ABCDE
Assess for shock
Monitor UO
CXR, ECG, ABG
pulse and BP, cardiac monitoring
Transfuse until haemodynamically stable 
Omeprazole 80mg bolus and IV 8mg/h for 3 days
Urgent endoscopy
OGD
Angiography
Surgery may be required if massive haemorrhage, failed initial endoscopic treatment with active bleeding, rebleeding, initial Rockall >3/final >6
Medical: IV PPI, stop NSAIDs, H pylori treatment,
23
Q

P and S prevention of GI bleeding

A

P - injection methods (adrenaline, NaCl, thrombin, fibrin sealant, sclerosants, thermal methods, endoscopic clips, variceal ligation)
S - avoid smoking and NSAIDs

24
Q

Causes of lower GI bleeds

A
Haemorrhoids / anal fissure
Infectious colitis
UC
Diverticulitis
Colorectal cancer / large polyps
Meckels, angiodysplasia, post radiotherapy procitis, aorto-enteric fistula, trauma
25
Q

Ix of lower GI bleed

A

FBC, U&E, LFT, clotting, amylase, CRP, G&S
Stool chart, sample for MC&S
Imaging: AXR, CXR, sigmoidoscopy/colonoscopy

26
Q

Acute Rx of rectal bleeding

A
ABC resus
Hx and exm
Fluid management (fluid replacement and monitor UO)
ABx if evidence of sepsis / perforation
PPI
Clear fluids for colonocopy
Surgery if unremitting, massive bleeding