GI Flashcards
The RUQ contains
Liver, gallbladder, ascending colon, kidney and pancreas (sm. amt)
The LUQ contains
Stomach, pancreas, descending colon, kidney
The RLQ contains
Appendix, ileum, cecum, ovary
The LLQ contains
sigmoid colon, ovary
What is a + psoas sign
RLQ pain is produced when pt raises their right leg against resistance of pressure from the practitioners hand or when they lie on their left side and extend the right leg from the hip
What does a + psoas sign indicate
Peritoneal irritation/peritonitis
What is a + obturator sign
Inward rotation of the hip causes RLQ pain
What does a + obturator sign suggest
Peritonitis
What is a + Rosvigs Sign
Deep palpation of the LLQ produces pain in the RLQ
What does a + Rosvigs sign suggest
Peritonitis
What is McBurney’s Point
the area between the superior iliac crest and umbilicus in the RLQ
What does tenderness at McBurney’s Point suggest?
Appendicitis
What is a + Markle’s Jar Test
Pt raises heels and drops them suddenly which produces pain, also positive if pt refuses to do this r/t pain
What is rebound tenderness
Worsening abdominal pain when hand is released after abdominal palpation compared with pain on deep palpation
What is Murphy’s sign
Press deeply on the RUQ under the costal margin during inspiration. Midinspiratory arrest is a + Murphy’s
What does a + Murphy’s sign suggest?
Cholecystitis
What is Carnett’s Sign
Pt does an abdominal crunch if this worsens pain then the source is the abdominal wall
Sx of Appendicitis
Acute onset of periumbilical pain, pain at McBurney’s pint, anorexia, low grade fever, RLQ, rebound tenderness, guarding
+Psosa, obturator, heel jar, Rosvigs, Rebound tenderness
What is the modality of imaging for appendicitis
CT
Sx of Cholecystitis
RUQ pain or epigastric pain that worsens within 1 hr after a fatty meal, nausea, vomiting and anorexia
What is the imaging modality for cholecystitis
Ultrasound
If U/S is inconclusive for cholecystitis what would you order
HIDA scan
What condition produces an elevation in bilirubin but normal LFTs
Gilbert’s syndrome
What are symptoms of colon cancer
Vague GI sx, may have IDA, changes in bowel habits/stools, bloody stools (heme +), dark tarry stools, mass on abdominal palpation
What is the gold standard screening for colorectal cancer?
Colonoscopy q10 years
Can also do FIT annually
What are the differences between Crohn’s and Colitis
Crohn occurs from mouth to anus, sx depends on affected area (watery diarrhea, bloody diarrhea, fever, anorexia, wt loss, dehydration, fatigue, periumbilical pain, fistuale, perianal disease
UC: Occurs in the colon/rectum
-sx: bloody diarrhea with mucus, cramps, bloating, gas, fever, anorexia, wt loss, fatigue, arthralgias, arthritis, IDA or anemia of chronic disease
Crohn’s and UC increase the risk of:
Colon cancer
Toxic Megacolon
What is GERD
acidic contents regurgitate from stomach into esophagus related to inappropriate LES relaxation
Food triggers for GERD
-chocolate, mints, caffeine, ETOH, carbonated drinks, tomatoes, citrus, fatty foods, spice
Med triggers for GERD
CCB, NSAIDs, nitrates, anticholinergics, iron, bisphosphonates, quinidines, theophylline, alpha adrenergic receptor agonists
Sx of GERD
- chronic heartburn
- associated with fatty or large meals
- worsens when supine
- acidic/sour taste in mouth
- thinning enamel
- chronic sore throat/cough
What is a complication of GERD
Barrett’s esophagus
What is the treatment of GERD
First Line: Lifestyle changes avoid large/fat meals, 3-4 hrs pre bedtime, avoid triggers, weight loss, smoking cessation
Pharm:
Antacid
H2 antagonist
PPI
What are longterm risks of PPI use?
Risk of osteoprosis, interstital nephritis, low magnesium, C. Diff, decreased iron absorption
When should you refer a patient with GERD
- No relief after 4-8 weeks after PPI use
- Sx associated with weight loss, difficulty swallowing, bleeding
C. Diff Diarrhea Risk Factors
- Prior or current antibiotic therapy
- Advanced age
- Hospitalization
- Chemo
What Abx are most likely to cause C. Diff
-Clindamycin, fluroquinolones, cephalosporin, penicillin
What are sx of C. Diff
-watery diarrhea, cramps, anorexia, nausea, low grade fever
What is the 1st line treatment for C. Diff
Vancomycin 125mg PO QID x 10 days
What is irritable bowel syndrome
A chronic functional disorder of the colon can be diarrhea or constipation dominant
What are treatments for IBS
- increase dietary fiber
- avoid gassy foods (ie. beans, onions, cabbage, high fructose corn syrup)
- antispasmodics (Dicylomine or hyoscyamine)
- Decrease anxiety and stress
Red Flags Diarrhea
- Bleeding
- Abdominal pain
- Weight loss
- Anemia
- Elevated inflammatory markers
- lyte disturbances
Risk factors for Colorectal cancer
- any polyps or hx of colorectal cancer
- IBD
- Family hx of CRC or polyps
What are RED FLAGS in Peptic Ulcer Disease
- Early satiety
- Anorexia
- Anemia
- Recurrent Vomiting
- Hematemesis
- Weight loss
What are sx of PUD
- recurrent epigastric pain
- Burning, gnawing ache
- Pain that is relieved by antacids or food
- Black tarry stools
- Blood in stools
- Coffee ground emesis
- IDA
What labs are indicated in PUD
- CBC
- FOBT
- H. Pylori (urea breath test)
- Upper endoscopy + Biopsy
What is the gold standard test for PUD
Upper endoscopy and biopsy
If a patient has multiple ulcers or are resistant to treatment, what should you test and what are you looking for?
- Gastrin levels
- Zollinger-Ellison Syndrome
What is the treatment for a Negative H. Pylori Ulcer
- smoking and ETOH cessation
- stop NSAIDs
- Combo lifestyle changes with PPI/H2 antagonist
- If no response x4-8 weeks refer
What is the treatment of a +H. Pylori Ulcer
- Quad Therapy
- Triple Therapy
Quad therapy consists of
- Bismuth 600mg QID
- Metronidazole 250mg QID
- Tetracycline 500mg QID
- PPI standard dose
Triple therapy consists of
- Clarithromycin 500mg BID
- Amoxicillin 1g BID or Metronidazole 500mg BID
- PPI standard dose
What is the difference in pain presentation between a gastric ulcer and a duodenal ulcer
- Gastic ulcers pain recurs shortly post meals
- Duodenal ulcers pain occurs 2-4hrs post meal
What are diverticula
Small pouch like herniations on the external surface of the colon, secondary to chronic fiber insufficiency
What is diverticulitis
Infection of diverticula (the small pouch like herniation on the external surface of the colon)
What are sx of diverticulitits
- LLQ pain
- fever
- If obstruction occurs, may have nausea +/- vomiting +/- ileus
What are labs are indicated in suspected diverticulitits
- CBC (will see left shift)
- FOBT (+)
What is the gold standard for dx diverticulitis
CT
What is the outpatient management of diverticulitis
- only outpatient in uncomplicated cases
- Liquid Diet
- Amox/Clav or Cipro & Flagyl
What is acute pancreatitis
Inflammation of the pancreas secondary to:
- ETOH
- Elevated triglycerides
- Gallstones
- Infections
A triglyceride level of ____ will cause a high risk of acute pancreatitis
800mg/dL
Sx of acute pancreatitis include:
- Fever
- N/V
- Abdominal pain with radiation to midback
- guarding
- tenderness
- Cullens
- Grey-Turner’s Signs
What is Cullen’s Sign
Bluish discoloration around the umbilicus
What is grey turner’s sign
Bluish discoloration around the flanks
What does IgM mean regarding immunity
Think “minute” as in you are recently infected
What does IgG mean regarding immunity
Thing “gone” as in you have immunity
Acute Hep A infection is indicated by:
IgM Anti-HAV
The presence of Hep A immunity is indicated by the following lab test:
IgG Anti- HAV
What does a + HBsAg mean
The patient has the virus and is currently infected
What does a + Anti-HBs mean
Patient is immune
What does HBeAg mean
Chronic Hep B infection
What does Anti-Hbc mean
- This appears at onset of Hep B infection and stays for life
- Can help you see whether immunity is from infection or vaccination
What is the screening test for Hep C
Anti HCV
If the Anti HCV is + what should you order
HCV RNA
If ALT and AST are elevated but ALT > AST think:
L- Liver
Likely hepatitis
If ALT and AST are elevated but AST > ALT think:
AST- Acetaminophen, statins, tequila aka drugs, statins and ETOH
What ration of AST:ALT make ETOH the most likely cause?
2
An elevation of AST ALT with a ratio of <1 is likely:
NAFLD
When is an elevation in ALP normal?
- In pregnancy
- Adolescents
Where is ALP found
Bones and liver
What is the gold standard for colorectal cancer screening?
Colonoscopy q10 years
What is NAFLD
- Hepatic steatosis without 2ndary cause
- Can progress to cirrhosis
What abdominal conditions warrant an X-ray
Ileus, obstruction, perforation
What abdominal conditions warrant an U/S
Gallbladder, pelvic organs, appendix*, liver
What abdominal conditions warrant a CT
Appendix, diverticulitis, acute abdomen
What abdominal conditions warrant an MRI
Hepatocellular carcinoma
Metastatic Disease
If an ultrasound is inconclusive for cholecystitis what is another test you can order to confirm
HIDA