GI

Question 1

male 22 yr with recurrent pulmonary infections and finger clubbing shows extensive exocrine gland atrophy and ficrosis
Pancreatic duct most likely def?

Answer 1

Vitamin A
Pt is suggestive of cystic fibrosis
severe CF&raquo_space; total obstruction จาก fibrotic atriphy of exocrine gland ได้&raquo_space;pancreatic insuf» def of fat soluble vitamin

Vit A contribute to squamous metaplasia of epithelial lining of pancreatic exocrine ducts
โดยปกติ vit A จะเป็นตัว maintain