GFR CKD: Staging

Question 1

GFR Range: G1

Answer 1

≥ 90 mL/min

Normal

Question 2

GFR Range: G2

Answer 2

60-89 mL/min

Mildly decreased

Question 3

GFR Range: G3a

Answer 3

45-59 mL/min

Mild –> moderately decreased

Question 4

GFR Range: G3b

Answer 4

30-44 mL/min

Moderate-severely decreased

Question 5

GFR Range: G4

Answer 5

15-29 mL/min

Severely decreased

Question 6

GFR Range: G5

Question 7

Albuminuria Categories: A1

Answer 7

ACR ≤ 30mg/g (≤ 3mg/mmol)

Normal

Question 8

Albuminuria Categories: A3

Answer 8

ACR ≥300mg/g (>30mg/mmol)

Albuminuria

Question 9

MDRD Limitations (6)

Answer 9

1. ) Amputees
2. ) Pediatrics
3. ) Elderly
4. ) Pregnancy
5. ) Unstable kidney Fx
6. ) Liver disease

Question 10

Wt for C-G if BMI > 40?

Answer 10

Lean BW (kg)

= (9270)(Total BW) / [6680 + (216 * BMI)] FOR MEN
= (9270)(Total BW) / [8780 + (244 * BMI)] FOR WOMEN

Question 11

Wt for C-G if BMI 30-40?

Answer 11

Adjusted BW (kg)

= Ideal BW + [0.4 * (Actual BW - Ideal BW)]

Question 12

Ideal BW

Answer 12

Men = 50kg + (Ht > 60in * 2.303)
Women = 45kg + (Ht > 60in * 2.303)

Question 13

Nephritic Kidney Disease: Diagnosis

Answer 13

Hematuria

Proteinuria (~1-3g/day)

Question 14

C-G GFR Estimation

Answer 14

DRUG DOSING purposes

Question 15

MDRD GFR Estimation

Answer 15

STAGING purposes

Question 16

MDRD Limitations (6)

Answer 16

1. ) Amputees
2. ) Pediatrics
3. ) Elderly
4. ) Pregnancy
5. ) Unstable kidney Fx
6. ) Liver disease

Question 17

Wt for C-G if BMI > 40?

Answer 17

Lean BW

= (9270)(Total BW) / [6680 + (216 * BMI)] FOR MEN
= (9270)(Total BW) / [8780 + (244 * BMI)] FOR WOMEN

Question 18

Wt for C-G if BMI 30-40?

Answer 18

Adjusted BW

= Ideal BW + [0.4 * (Actual BW - Ideal BW)]

Question 19

Ideal BW

Answer 19

Men = 50kg + (Ht > 60in * 2.303)
Women = 45kg + (Ht > 60in * 2.303)

Question 20

Nephritic Kidney Disease: Diagnosis

Answer 20

Hematuria

Proteinuria (~1-3g/day)

Question 21

Nephrotic Kidney Disease: Diagnosis

Answer 21

EXTREME Proteinuria (>3g/day)

• Edema
• Hyperlipidemia
• Hypercoaguable state

Question 22

When to use: Cockcroft-Gault Equation (CkG)

Answer 22

Dosing purposes

-may be inaccurate for low muscle mass (round to 1.0mg/mL for estimation purposes)

Question 23

When to use: MDRD

Answer 23

(online estimation tool)

Question 24

Imput factors for MDRD (website)

Answer 24

1. ) Age
2. ) Sex
3. ) Race
4. ) SrCr or Cystatin C