Gestational Condition Flashcards
Hypertension in Pregnancy: Significance & Incidence
- Preeclampsia complicates approx. 5-10% of all pregnancies
-
HTN disorders of preg are the most common medical complication reported during preg
> hemorrhagic/SI are 2nd & 3rd - Significant contributor to maternal & perinatal morbidity & mortality
Gestational Hypertension
- Develops after 20th wk of preg w/out proteinuria
- Need more than 1 HTN reading
Chronic Hypertension
& risk for, & fetal effects
- HTN before pregnancy or diagnosed before 20 wks
-
Risk for
> placental abruption
> superimposed preeclampsia: development of preeclamp from HTN
> incrd perinatal mortality -
Fetal Effects
> growth restriction
> preterm birth
Preeclampsia
-
HTN & proteinuria develops after 20wks
or -
HTN w/ end organ damage
> renal/liver
Eclampsia
- Seizure activity or coma in women diagnosed w/ preeclampsia
-
No previous hx
> or pre-existing patho of seizure disorder - Eclamptic seizures can occur before, during, or after birth
Chronic HTN w/ Superimposed Preeclampsia
- A sudden incr in blood pressure tht was previously well-controlled
- New-onset proteinuria or a sudden & sustained incr in proteinuria in a women known to have proteinuria before conception or early in pregnancy
Preeclampsia - Pathophysiology
- Disruptions in placental perfusion & endothelial cell dysfunctions
-
Placental itching (spasm)
> = small baby -
Generalized vasospasm
> incrd risk of clots - Spiral arteries don’t remodel to allow for incrd blood flow
-
Reduced kidney perfusion
> protein in urine
> generalized edema
Preeclampsia - Etiology
S/S only develop during pregnancy and disappear after birth
Preeclampsia - Risk Factors
- Fam hx
- Multifetal pregnancy
- African-American race
- Obesity
- 19-40yrs
- Any pre-existing medical or genetic conditions
Preeclampsia: HELLP Syndrome
-
Lab diagnostic variant of severe preeclamp involves hepatic dysfunction, characterized by:
> Hemolysis (H)
> Elevated liver enzymes (EL)
> Low platelets (LP)
Preeclampsia: HELLP Syndrome - Associated w/ Incrd Risk For
- Pulm edema
- Renal failure
- Liver hemorrhage or failure
-
Disseminated intravascular coagulation (DIC)
> use up all clotting factors; bleed out of all holes - Placental abruption
- Acute resp distress syndrome
- Sepsis
- Stroke
- Fetal & maternal death
Identifying & Preventing Preeclampsia
LILI LUK
-
Physical Examination
> dependent, pitting edema
> DTR (clonus): suppose to be negative
> blurred/double vision
> RUQ pain: liver ischemia
> listen to lungs/HR: pulm edema
> SOB -
Lab Tests
> urine output (oliguria)
> kidney labs (Cr/proteinuria)
> low platelets
> incrs factor 8
> liver func tests
> lipids incrd
> incrd Hct
Mild Gestational HTN & Mild Preeclampsia
treatment
diet
-
Treatment:
> BP control
> May have some restriction
> Maternal/fetal assessment -
Diet
> don’t reduce salt
Severe Gestational HTN & Severe Preeclampsia
cure
med
-
Cure
> delivery -
Drug used during delivery to prevent eclampsia
> magnesium sulfate: prevent & treat a seizure - severe GHTN & preeclamp put pregnancy at greater risk for complications
> control BP
Magnesium Sulfate
how to admin
therapeutic lvls
excretion
- Drug of choice for prevention & treatment of eclampsia
-
Administered almost excusively IV
> 4-6gram loading dose over 15-20mins
> followed by maintenance dose of 2gram/hr after delivery
> big bore IV -
Therapeutic lvls
> 4-7mEq/L -
Excreted by kidneys
> if compromised, lvls will rise
> watch I&Os for toxicity
Magnesium Sulfate - Adverse Effects
- Warming
- Flushing
- Diaphoresis
- IV site irritation
- may need Pitocin to help contract since mag causes relaxation
Magnesium Sulfate - Mild Toxicity
- Appears drunk:
- Lethargy
- Muscle weakness
- Dcrd DTRs
- Double vision
- Slurred speech
- draw labs, watch I&Os
Magensium Toxicity - Severe Toxicity
- Maternal hypotension
-
Bradycardia
> dcrd HR -
Bradypnea
> dcrd RR - Cardiac arrest
Magnesium Toxicity - Managing Toxicity
-
Discontinue infusion
> priority - Notify HCP
-
Administer Calcium Gluconate
> antidote
Hyperemesis Gravidarum - Define
- Excessive vomiting accompanied by dehydration, electrolyte imbalance, ketosis, & acetonuria
- last entire pregnancy
Hyperemesis Gravidarum - Etiology
- Relaxation of the smooth muscle of the stomach
- Incrd hCG lvls
Hyperemesis Gravidarum - CMs
- Weight loss <5%
- Dehydration
- Electrolyte imbalance
Hyperemesis Gravidarum - Care Management
- IV fluids
- Pyridoxine (vit B6)
Hemorrhagic Disorders - Maternal Risks
- Hemorrhagic disorders in pregnancy are medical emergencies
-
Maternal blood loss dcrs oxygen-carrying capacity
> incrd risk for: hypovolemia, anemia, infection, preterm labor & birth
> adversely affects oxygen delivery to fetus
Hemorrhagic Disorders - Fetal Risks
Fetal risks includes blood loss or anemia, hypoxemia, hypoxia, anoxia, & preterm birth
Spontaneous Abortion
Spontaneous abortions often lead to a D&C
Reduced Cervical Competence (Cerclage)
- A procedure in which the cervical opening is stitched closed to prevent or delay preterm birth due to premature dilation
-
Prophylactic Cerclage
> placed at 11-15wks of gestation
Ectopic Pregnancy
- Fertilized ovum implanted outside the uterine cavity
- Most occur in fallopian tube(Ampulla)
Ectopic Pregnancy - CMs
- Abdominal pain
- Delayed menses
- Abnormal vaginal bleeding
- Unilateral pelvic pain
Ectopic Pregnancy - Management
-
Medical
> Methotrexate: stops growth and prevents rupture -
Surgical
> Salpingectomy: removal of one or both fallopian tube, cannot come to term
Gestational Trophoblastic Disease - Define
& education
-
Define: abnormal fertilization w/out viable fetus
> tumor, mass of cells -
Education:
> risk for developing a type of cancer
> measure hCG for a year
> don’t get pregnant for next year: monitoring hCG
Gestational Trophoblastic Disease - CMs
- Vaginal bleeding
- Significantly larger uterus
Gestational Trophoblastic Disease - Management
- Most end up passing spontaneously
- Suction curettage (D&C) is safe, rapid, and effective if necessary
- Do NOT recommend induction of labor w/ oxytocin or prostaglandins
Late Pregnancy Bleeding: Placenta Previa - Define
& fetal risks
- Placenta implanted in LOWER uterine segment near or over interal cervical
- Excessive bleeding
- Fetal risks include malpresentation, preterm birth, fetal anemia, & congenital anomalies
Late Pregnancy Bleeding: Placenta Previa - Classification & CMs
-
Classified based on
> complete; more painless bleeding
> marginal -
CMs
> abnormal placental attachment
> excessive bleeding: ask if painful
Late Pregnancy Bleeding: Placenta Previa - Diagnosis
Transabdominal ultrasound examination
Late Pregnancy Bleeding: Placenta Previa - Management
-
Expectant management: observation & bed rest
> no treatment unless symps appear -
Alternative birth:
> cesarean birth
> home care -
Active Management:
> birth regardless of gestational age if excessive bleeds or complications arise
Late Pregnancy Bleeding: Abruptio Placentae - Define
- Premature separation of placenta
- Biggest concern w/ pre-existing conditions & trauma
Late Pregnancy Bleeding: Abruptio Placentae - Classifications
- Grade 1 (mild)
- Grade 2 (moderate)
- Grade 3 (severe)
Late Pregnancy Bleeding: Abruptio Placentae - CMs
-
Vaginal bleeding
> very painful - Abdominal pain
- Uterine tenderness
- Contractions
Late Pregnancy Bleeding: Abruptio Placentae - Maternal Outcomes
- Blood loss
- Coagulopathy
- Need for transfusion
- End-organ damage
Late Pregnancy Bleeding: Abruption - Etiology
- Maternal HTN, chronic or pregnancy related, is the most common risk factor
- Drugs/trauma
Late Pregnancy Bleeding: Abruptio Placentae - Fetal Outcomes
-
Fetal growth restriction
> low birth weight, organ dysfuntion -
Oligohydramnios
> low amniotic fluid - Preterm birth
-
Hypoxemia
> low oxygen in blood - Stillbirth
Late Pregnancy Bleeding: Abruption - Management
- Depends on severity, if stable they will just watch
- Unstable then active management & delivery required
Disseminated Intravascular Coagulation (DIC) - Pathophysiology
- Diffuse clotting causing widespread external & internal bleeding
-
Triggered by large amounts of tissue thromboplastin
> placental abruption or dead fetus -
Triggered by widespread damage to vascular integrity
> severe preeclampsia, HELLP, gram neg sepsis
Disseminated Intravascular Coagulation (DIC) - Management
- Correction of underlying cause
- Volume expansion
- Rapid replacement of blood products and clotting factors
- Optimization of oxygenation
- Continued reassessment of lab parameters
Trauma During Pregnancy - Maternal Physiologic Characteristics
- Requires strategies adapted for appropriate resuscitation, fluid therapy, positioning, assessments:
-
Cardiac Output
> could have no signs of shock until more than 30% of blood lost -
Circulating Blood Volume
> can lose 1000mL of blood -
Decreased Intolerance for Hypoxia Apnea
> risk for acidosis -
Uterus & Bladder Positioning
> risk for vena caval compression in supine -
Elevated Lvls of Progesterone
> relaxes LES and an incr in hydrochloric acid, can result in aspiration, protect airway
Trauma During Pregnancy - Fetal Physiologic Characteristics
- Careful monitoring of fetal status assists greatly in maternal assessment
- Fetal monitor tracing works as “oximeter” of internal maternal well-being
Trauma During Pregnancy - Nursing Care Management
- Immediate stabilization
-
Primary Survey
> cardiopulm resuscitation - Seconday survey
- Electronic fetal monitoring
-
Fetal-maternal hemorrhage
> ultrasound
> radiation exposure - Perimortem cesarean delivery