Gero 2 Flashcards
Strategies for engineered negligible senescence SENS)
Aubrey de Grey Challenges the most basic assumptions underlying they human condition that aging is inevitable. He argues instead that aging is a disease, one that can be cured if it is approached as an “engineering problem. His plan calls for identifying all the components that cause human tissue to age and designing remedies for each of them forestalling disease and eventually pushing back death
Stroke
Cerebrovascular accident (CV) The rapid loss of brain function due to disturbance in the blood supply to the brain. This can be due to ischemia (lack of blood flow) caused by blockage or hemorage. As a result, the affected area of the brain cannot function, which might result in an inability to move one or more limbs on one side of the body, inability to understand or formulate speech or an inability to see one side of the visual field. High blood pressure is the most important modifiable risk factor. 2nd leading cause of death worldwide
Life cycle
The entire course of a person’s life, from infancy to old age. Health, social roles, expectations, and socioeconomic status tend to change as an individual develops.
Life expectancy
Average amount of time of life remaining for a population whose members all have the same birth date
Telomeres
A series of repetative DNA sequences and specialized proteins that cap the ends of chromosomes and get shorter with each cell division. When they get too short, the cell stops dividing and dies.
Telomere theory
Non-stochastic Each time a cell divides, the DNA unwraps, and the information within is copied. Because of how cells divide, that very last bit of a chromosome, the telomere, cannot be completely copied. A little bit has to be cut off. It is thought that, as a cell divides, the telomeres become shorter and shorter each time until they are gone. At this point, the so-called “real” DNA cannot be copied anymore, and the cell simply ages and is no longer able to replicate. Cancers, negative lifestyle choices, and cell mutations can speed up telomere shortening
Thermoregulation
A process that allows your body to maintain its core internal temperature. All thermoregulation mechanisms are designed to return your body to homeostasis. This is a state of equilibrium. A healthy internal body temperature falls within a narrow window.
Verbal report
Reports of behavior from some knowledge source. This could be from interviewing, focus groups and related means for gathering data, directly by asking participant.s There are no direct measures of behavior which may sometimes be innacurate.
Variance
Measure of variability. A statistical measure of how much a set of observations differ from each other.
Veracity
The principle of truth telling, and it is grounded in respect for persons and the concept of autonomy. In order for a person to make fully rational choices, he or she must have the information relevant to his or her decision.
Time-lag design
A study that examines the responses of different participants of similar age at different points in time. Time-lag is one of the three methods used to study developmental and generational change.
Tinnitus
A condition causing the perception of ringing in the ear. Multiple causes (MS, ear infection, wax build up.) Common among adults 55-65 years of age
Mental illness in aging
Two paths: Life long illness: schizophrenia, bipolar disorder, schizo-affective disorder, borderline personality disorder, panic disorder, OCD, PTSD. Later-onset illness: depression, dementia/cognitive impairment, anxiety, alcohol/substance abuse, sexual and sleep disorders, adjustment disorder, complicated grief.
Type I Error
Reporting significant difference when there wasn’t one; also known as a false positive. The researcher reporting that the relationship is significant when in fact it was not. This is more serious methodological error.
Type II Error
Reporting that there was no difference when in fact there was a difference, also known as a false negative. The researcher is reporting that the relationship is not significant when in fact it really is.
