Germ Layers

Question 1

When is gasturlation? What are the first layers formed?

Answer 1

End of the second week

two flat layers:
Epiblast
Hypoblast

Question 2

Epiblast

Answer 2

All embryonic tissue and some extraembryonic tissues

Ectoderm
Mesoderm
Endoderm

Express nanog

Question 3

Hypoblast

Answer 3

Extraembryonic endoderm

Gata 6 - induced by FGF-4

Question 4

Cells that become the first inner cell mass cells express nanog which destines them for what development?

Answer 4

To become epiblast

Question 5

What is Gata-6 effect on the developing gasturla?

Answer 5

Induces later inner cell mass cells to become hypoblast

Gata 6 expression induced from FGF-4 from early ICM cells

Question 6

What two molecules induce development of the primitive streak?

Answer 6

TGF-β and Wnt

Question 7

What are bottle cells?

Answer 7

Epithelial cells that travel the epiblast and through the primitive streak and changes shape, bottle, then -dendrity- as a mesenchymal cell.

Tf snail