Geriatric Pharmacotherapy Flashcards
What are the 45 Ms we should keep in mind when caring for geriatric patients?
What Matters
Mobility
Medication
Mentation
Multi-complexity
How is GI absorption different in geriatric pateints?
No significant change
Time of inset or peak may be delayed
How is intramuscular absorption different in geriatric patients?
decreased IM absorption because of lower muscle mass and peripheral circulation, and increased connective tissue
How is topical absorption different in geriatric patients?
Decreased topical absorption due to lower skin hydration and increased keratinization
How is medication distribution different in geriatric patients?
increase in distribution of lipid soluble medications but a decrease in distribution of water soluble medications
How is protein binding different in geriatric patients?
less albumin and protein affinity will lead to increase free fraction of highly protein bound medications
Geriatric patients have a ________ metabolism compared to adults
slower
How is renal elimination different in geriatric patients?
renal function is decreased significantly by more than 50%
What drugs can increase the risk of falling for geriatric pateints?
- any CNS depressants
- benzodiazepines (-azepam)
- sedatives
- anti-psychotics
Effects of cholinergic drugs
SLUDD
Salivation, Lacrimation, Urination, Defacation, Digestive
The systolic blood pressure of a healthy geriatric patient is recommended to be …?
<130
