GERD Flashcards

0
Q

heart burn, acid taste, belching

A

GERD

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1
Q

pathophysiologies of GERD (4)

A

transient relaxation of LES
acid hypersecretion in stomach
decreased gastric emptying
hiatal hernia

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2
Q

atypical symptoms of GERD (5)

A
chest pain
hoarseness
dental enamel decay
asthma/cough
dyspepsia
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3
Q

GERD complications (3)

A

dysphagia
odynophagia
hematemesis

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4
Q

tx for unexplained angina or asthma?

A

PPI

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5
Q

when to perform GERD diagnostic?

what is the preferred GERD diagnostic?

A

uncertain diagnosis, atypical/complicated symptoms, refractory, before surgery

endoscopy

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6
Q

what can be seen with a barium swallow? what can’t?

A

yes: hiatal hernia, strictures
no: esophagitis, Barrett’s epithelium

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7
Q

what is the best study to confirm GERD?

A

ambulatory pH monitoring

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8
Q

what diagnostic study assesses LES pressure and peristalsis?

A

esophageal manometry

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9
Q

lifestyle tx for GERD (4)

A

elevate head of bed
no food 3h before bed
smoking cessation
decrease fat and vol. of diet

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10
Q

H2 receptor anatagonists (4)

A

Cimetidine
Ranitidine
Famotidine
Nizatidine

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11
Q

PPIs (suffix)

A

-prazoles

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12
Q

what is Barrett’s esophagus?

A

a specialized type of intestinal metaplasia- replacement of squamous epithelium with columnar epithelium due to recurrent acid injury

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13
Q

what is a result of Barrett’s esophagus?

A

esophageal adenocarcinoma

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14
Q

progressive dysplasia while eating solid foods can indicate?

A

esophageal carcinoma

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15
Q

etiology of esophageal adenocarcinoma

A

Barrett’s esophagus

16
Q

odynophagia, constant chest/back pain, regurgitation, anorexia, wt. loss, malnutrition

A

esophageal carcinoma

17
Q

most common type of esophageal cancer?

A

squamous cell carcinoma

18
Q

risk factors for esophageal squamous cell carcinoma (4)

A

hx tobacco/EtOH use
ingestion of caustic substances
chronic esophagitis
nutritional deficiencies

19
Q

diagnosis of esophageal carcinoma? (2)

A

endoscopy

stage w/ CT