Georgette’s Flashcards

1
Q

Benefits of Lithium treatment

A

Gold standard for treating manic episodes

Neuroprotective

Antisuicidal effect

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2
Q

Normal serum values for lithium

A

0.5 to 1.2 mEq per liter

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3
Q

Common Baseline labs before initiation with lithium

A

Thyroid panel (Hyperthyroid can appear as mania)

Serum creatinine (0.6 to 1.2 mg/dL)

BUN (10 to 20 mg/dL)

Urinalysis (Large amount of protein in urine (+4) May indicate kidney disease

Pregnancy test (12 to 51 years of age are considered child bearing)

ECG for clients >than 50

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4
Q

Clinically significant side effects of lithium

A

Hypothyroidism
Course hand tremors with toxicity
Maculopapular rash
Diarrhea, vomiting, cramps, anorexia
Polyuria with related polydipsia
T-wave inversion
Leukocytosis

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5
Q

Carbamazepine (Tegretol) Black box warning for

A

Agranulocytosis (low WBCs) and Aplastic anemia (deficiency of all types of blood cells)

pallor, fatigue, headache, nose bleeds, bleeding gums, skin rash, shortness of breath

Steven Johnson syndrome particularly in Asians (Screen for HLAB1502 allele before initiation)

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6
Q

A hypertensive crisis occurs when

A

MAOIs are taken in conjunction with certain medication’s

Common medication include: Meperidine (Demerol), stimulants, decongestants, asthma medication,

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7
Q

Symptoms of hypertensive crisis include

A

Sudden, explosive like headache, usually in occipital region

 Hypertension, Flushing, palpitations, diaphoresis, fever

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8
Q

Treatment of hypertensive crisis includes

A

Discontinuing the MAOI

Phentolamine (Blocks by binding to norepinephrine receptor sites)

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9
Q

The treatment for serotonin syndrome

A

Cryptoheptadine (antihistamine)

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10
Q

Cardinal sign of serotonin syndrome is

A

Cardinal sign of serotonin syndrome is myoclonic jerking, hyper reflexia, confusion, shivering, goosebumps, tachycardia and hypertension

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11
Q

Teratogenic risks of benzodiazepines

A

Floppy baby syndrome, cleft palate

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12
Q

Teratogenic risks of carbamazepine

A

Neural tube defects

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13
Q

Teratogenic Risk of lithium

A

Ebstein anomaly

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14
Q

Teratogenic risk of Depakote

A

Spina bifida

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15
Q

For patients taking clozapine and/or carbamazepine (tegretol), Risk for neutropenia is monitored by which lab value

A

ANC only

DC Clozapine at ANC less than 1000 (Neutropenia) Regardless of whether the patient is showing signs of infection or not

DC clozapine at wbc’s 2000 to 3000 (Agranulocytosis)

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16
Q

For patients taking clozapine, what should the patient be closely monitored for

A

Signs of infection (Fever, chills, sore throat, weakness)

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17
Q

What is normal BMI

A

18.5 to 24.9

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18
Q

A BMI less than —— requires hospitalization

A

<15

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19
Q

Physical exam findings for anorexia

A

Low BMI
Russells sign (Calluses on dorsum of hand secondary to Induced vomiting)
Brittle hair and nails
Lanugo on face extremities and trunk
Amenorrhea
Emaciation
Bradycardia
Hypotension

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20
Q

BMI for a patient with bulimia nervosa is usually

A

Normal

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21
Q

As Wellbutrin is know to have more or less sexual side effects

A

Less sexual side effects because it is an NDRI

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22
Q

Which antidepressant is appropriate for patients experiencing depression with low energy and fatigue

A

Wellbutrin

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23
Q

Which antidepressant is contraindicated in patients with a history of seizure or anorexia/bulimia

A

Wellbutrin. Wellbutrin decreases seizure threshold

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24
Q

What are some known cytochrome P450 inhibitors

A

Pneumonic: SICK FACES.COM

Sodium valproate
Indomethacin
CLARITHROMYCIN/ Cimetidine
Ketoconazole

Fluconazole
alcohol
Chloramphenicol
ERYTHROMYCIN
Sulfonamide

Cipro
Omeprazole
Metronidazole

Grapefruit juice
Wellbutrin 

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25
What are some common cytochrome P450 inducers
CARBAMAZEPINE (TEGRETOL) Tobacco Phenobarbital Dilantin Oral Contraceptives Pneumonic: BS CRAP GPS Barbiturates , St. John’s wort, carbamazepine,  rifampin, alcohol, phenytoin, Griseofulvin,  Phenobarbital, sulfonylureas 
26
Which common antipsychotic is metabolized by cytochrome P450 enzyme CYP1A2
Clozapine (Clozaril)
27
Which medications are known to reduce renal clearance
Indocin (NSAID) Ibuprofen Thiazides Ace inhibitors
28
Why are older adults more sensitive to psychotropic medication
Most psychotropic medications are lipophilic and highly protein bound Older adults have more body fat and less protein which makes them more likely to develop toxicity to two accumulation of medications Also, older adults have slower metabolism and less muscle mass
29
Pharmacodynamics is
What a medication does to a persons body
30
An agonist does what
Binds to receptors and activates a biological response
31
An inverse agonist does what
Has the opposite effect of an agonist. Inverse agonists do not bind to receptors
32
Partial agonist do what
Does not fully activate the receptor
33
Antagonists do what
Bind to the receptor but does not activate it biological response
34
A BMI greater than 30 indicates
Obesity
35
In which areas of the brain is dopamine produced
Substantial nigra ventral tegmental nucleus accumbens 
36
In which area of the brain is norepinephrine produced
Locus ceruleus medullary Formation reticular formation
37
In which area is serotonin produced
Raphae nuclear of the brain stem
38
Glutamate is considered the universal
Excitatory neurotransmitter
39
GABA is considered the universal
Inhibitory neurotransmitter
40
Acetylcholine is synthesized by which area
The basil nucleus of Maynert 
41
Increased levels of corticotropin releasing hormones in which areas of the brain will increase symptoms of anxiety
Increased levels of corticotropin releasing hormone in the amygdala, hippocampus, and Locus coeruleus will increase symptoms of anxiety
42
The follow up care of the patient with ADHD should include
Monitor clinical progress overtime  Use standardized reading scales (Vanderbilt, Connors which both include parent and teacher input)
43
Autism spectrum disorder is best defined as
Persistent deficits in social communication and social interaction across multiple settings
44
Assessment findings you would expect to see in autism spectrum disorder includes
No response when called by name Little or no eye contact Non-verbal communication Often likes to lineup, stack, or organize objects and toys
45
Common Screen tools used for autism spectrum disorder equal
Modified checklist for autism in toddlers (M-CHAT) Autism diagnostic observation schedule -Generic (ADOS-G) Ages and stages questionnaire’s (ASQ)
46
Pharmacological management in autism spectrum disorder may include
Antipsychotics which are affective for symptoms such as tantrums, aggressive behavior, self-injurious behavior, hyperactivity, and repetitive stereotypes behaviors
47
The corpus callosum is
An area of sensorimotor information exchange between the two hemispheres Of the cerebrum
48
Each hemisphere of the cerebrum is divided into four major lobes which are
Frontal lobe Temporel lobe Occipital lobe Parietal lobe
49
Functions of the frontal lobe include
Executive function: Working memory, reasoning, planning, prioritizing, sequencing behavior, insight, flexibility to come in judgment, impulse control Language (Broca’s area) expressive speech
50
Disturbances of the frontal lobe can lead to
Personality changes, emotional and intellectual changes
51
Temporal lobe functions include
Language (Wernicke’s area) speech reception, language comprehension, Memory, facial recognition, Hearing, Speech, emotion
52
Functions of the Frontal lobe
Thinking, planning, problem-solving, emotions, Behavioral control, Decision making
53
Z
54
Functions of the Parietal lobe
Perception, object classification, spelling, Knowledge of numbers, Visual-spatial processing
55
Functions of the Occipital lobe
Vision, visual processing, color identification
56
Functions of the Cerebellum
Gross and fine hand motor skills, hand to eye coordination skills, and balance
57
Functions of the brain stem
Regulates body temperature, heat rate, breathing, swallowing
58
The clock drawing test 
Take a minute or two to complete Quick screen for possible dementia / Alzheimers Difficulties with the clock drawing test indicates constructional apraxia / lesions to the right parietal lobe 
59
The limbic system Lies within the cerebrum and is composed of the
Thalamus, hypothalamus, Hippocampus, and amygdala
60
The function of the limbic system is to
Regulate and modulate emotions and memory
61
The function of the hypothalamus is two
Regulate appetite, circadian rhythm and libido
62
The function of the hippocampus is to
Regulate motivation, stress, emotion Regulate memory and convert short-term memory into long-term memory
63
The function of the amygdala is
Mediation of fear, anxiety, aggression, and rage Mediation of mood, fear, emotion, and aggression
64
 A typical antipsychotics antagonize the
they (block) the 5HT2a serotonin receptor
65
mesolimbic dopamine pathway
Excess dopamine causes positive psychotic symptoms Antagonism of D2 receptors in the mesolimbic pathway helps decrease the positive symptoms of psychosis
66
Mesocortical dopamine pathway
Decreased dopamine in the mesocortical pathway causes negative and depressive symptoms of schizophrenia
67
Nigrostriatal dopamine pathway
The nigrostriatal dopamine pathway mediates motor movements The blockade of D2 receptors in this pathway leads to the development of extrapyramidal symptoms (EPS) because of inverse rise in acetylcholine levels (inc salivation, teary eyes, diarrhea) Long-standing blockade of D2 receptors in the nigrostriatal pathway can lead to tardive dyskinesia
68
Tuberoinfundibular dopamine pathway
Blockade of D2 receptors in this pathway can lead to increased prolactin levels which causes galactorrhea (risperidone), amenorrhea, gynecomastia, sexual dysfunction. Long term hyperprolactinemia can lead to osteoporosis
69
Types of EPS (extrapyramidal symptoms) include:
Dystonia (Sustained muscular skeletal contractions) Oculargyric crisis, tortacollis Akathisia (ants in pants) Parkinsonism (same symptoms as Parkinson’s) Tardive dyskinesia (repetitive oral and tongue smacking)
70
EPS is caused by
excessive D2 blockade (antagonism) from antipsychotic therapy Decreased dopamine = Increased acetylcholine (remember inverse relationship)
71
Treatment of EPS includes
Anticholinergics like benztropine (Cogentin) for dystonia and Parkinsonism Beta blockers for akathisia Treatment of Tardive Dyskinesia is to stop or reduce the current dose of antipsychotic or start an atypical antipsychotics. Treatment can also include valbenazine (Ingrezza). Never give benztropine for TD. It can worsen TD
72
Occulogyric crisis
A rare form of dystonia which can lead to permanent injury and involves prolong involuntary upward deviation of the eyes Treatment is benztropine (Cogentin)
73
Neuroleptic malignant syndrome is
A type of EPS typically caused by taking too much of a first generation antipsychotic which decreases levels of dopamine too greatly severe muscle rigidity which can cause rhabdomyolysis, MUTISM, Fever, tachycardia, confusion Labs: CPK (elevated from muscle contraction and muscle distraction) myoglobinuria, elevated WBCs (Leukocytosis) elevated LFTs Treatment is discontinue the antipsychotic. Then give dantrolene (muscle relaxer) and a D2 agonist (like bromocryptine) to increase dopamine levels
74
To commonly used rating scales for the severity of akathisia are
The Barnes Akathisia rating scale Extrapyramidal Symptom rating scale 
75
Which antidepressant is associated with the most adverse cardiovascular side effects
citalopram (Celexa) 2011 warning about prolonged QTC intervals in doses greater than 40 mg (>20mg in older adults)
76
The study of a drug absorption, metabolism, distribution, and excretion is called
Pharmacokinetics
77
The study of what a drug does to the body is
Pharmacodynamics
78
Hallmark sign of fetal alcohol syndrome is
Underdeveloped features (Small head circumference, small eye openings, small nose, Small lips, low nasal bridge, epicanthal skinfolds,
79
Absorption is defined as
Method and rate and which drugs leave the site of administration. With oral medications absorption normally occurs in a small intestine and then the liver
80
Distribution is defined as
When the drug leaves the systemic circulation and enters the interstitium and cells Most psychotropic medication’s are lipophilic and highly protein bound. Only the unbound portion of the drug is active Patients with low protein levels related to malnutrition, aging can potentially experience toxicity
81
Which classification of medications is moved commonly associated with mania like side effects?
Steroids (Flonase, prednisone)
82
Which classification of medication is most commonly associated with depression like side effects
Steroids (Flonase (fluticasone), prednisone)
83
Isotretionoin (Accutane) Is associated with which two side effects?
Depression Birth defects (patients who are pregnant and taking Accutane should be recommended to stop immediately)
84
Propranolol is known to exacerbate or cause which psychiatric diagnosis
Depression
85
A physical description of a patient with fragile X syndrome would include
A description of larger structures Large, long head and ears. Macrorchidism (Abnormally large testes) Hyper extensible joints Crossed eyes (Strabismus), Highly arched palette
86
Tricyclic antidepressants are known to cause what and should be avoided in patients with a history of what?
TCAs are known to cause EKG changes and cardiac dysrhythmias Should be avoided in patients with history of cardiac dysrhythmias If necessary in this population EKG should be monitored before treatment begins and annually
87
What causes a hypertensive crisis
MAO eyes are taken in conjunction with certain medication‘s Meperidine (Demerol) Can result in coma or severe respiratory depression Stimulants and other sympathomimetics (Amphetamines, cocaine) TCAs, atypical antipsychotics
88
What are the symptoms of a hypertensive crisis
Sudden, explosive like headache, usually in occipital region Hypertension, palpitations, pupillary dilation, diaphoresis, fever, Flushing
89
What is the treatment for a hypertensive crisis
Discontinue the MAOI Give phentolamine (Blocks norepinephrine)
90
What causes serotonin syndrome
Taking too much of an Antidepressant (SSRI, MAOI, TCA, SNRI) TRIPTANS (Migraine medication) Imitrex (sumatriptan) At John’s Wort
91
What are the symptoms of serotonin syndrome
Hyperreflexia, myoclonic jerking, loss of coordination Agitation, restlessness, palpitations, rapid heart rate, hypertension, headache, sweating, shivering, goosebumps Confusion, fever, seizures, unconsciousness
92
 What is the treatment for serotonin syndrome
Discontinue the offending agent and provide support of treatment including Judicious use of benzodiazepines Serious overdose may require Cryptoheptadine (Anti-histamine) , and anticonvulsants 
93
When switching from an SSRI to an MAOI how long should a practitioner have the patient weight
14 days
94
When switching from Prozac to an MAOI how long should the practitioner have the patient wait
5 to 6 weeks
95
When switching from an MAOI back to Prozac how long should a practitioner have the patient wait
Two weeks
96
When switching medication’s a good rule of thumb is to always wait at least how many days regardless of drug class
14 days
97
When switching from Prozac is best to wait how long because of Prozac’s long half life
5-6 weeks
98
Serotonin discontinuation syndrome is caused by
Abrupt discontinuation
99
Symptoms of Serotonin discontinuation syndrome 
Flu like symptoms Fatigue and lethargy Myalgia Decreased concentration 
100
Which Antidepressant Is most likely to cause discontinuation syndrome if stopped abruptly
Zoloft (sertraline) has a short half-life so discontinuation syndrome is more likely
101
Delusions are defined as
Firmly maintained false beliefs despite evidence to the contrary
102
Paranoia is defined as
Believing that people are out to get you
103
Referential thinking is defined as
The belief that Cues and events in a patient’s every day life Have special meaning just for them
104
Components of mental status exam
Appearance Behavior Speech Mood Affect Thought process Thought content
105
Thought process as part of the MSE is defined as
Assessment of the patient’s organization of thoughts and ideas 
106
Tangential thought process as part of the MSE is defined as
Moving from thought to thought in a way that may or may not relate to the question and never gets to the point
107
Circumstantial thought process as part of the MSE is defined as
Providing unnecessary detail but eventually answering the question
108
Thought content as a part of the mental status exam is defined as
Themes that occupy the patients thoughts and perceptual disturbances Examples: SUICIDAL IDEATION, HOMICIDAL IDEATION, auditory or visual hallucinations
109
MMSE (Folstein scale) uses what to assess concentration, calculation, and attention?
Counting backwards from 100 by 7 (Serial 7’s)
110
MMSE (Folstein scale) uses what to assess registration (Ability to learn new material)
Slowly and clearly say the names of three unrelated objects. Ask the patient to repeat them
111
The MMSE (Folstein scale) defines registration as
The ability to learn new material
112
The MMSE (Folstein scale) uses what to assess fund of knowledge
Ask the patient who the current president is
113
Appraisal of the patient suicidal ideation, plan, method, intent would be documented in which part of the patients psychiatric evaluation?
Mental status exam
114
Which demographic group is at the highest risk of suicide 
Older, single, white, males, with depression
115
Treatment for alcohol withdrawal begins with a CIWA score of
8 or greater for (prn only) 15 or greater for (scheduled + prn) Diazepam and lorazepam are commonly used.
116
Which three medications are approved by the FDA for the treatment of alcohol use disorder
Acomprosate (campral) Disulfiram (Antabuse) Naltrexone (vivitrol)  Acomprosate and naltrexone decrease Alcohol consumption
117
Signs and symptoms of withdrawal according to the clinical opioid withdrawal scale (COWS)
Yawning ability/anxiety Myalgia Pupillary dilation Pilo erection Lacrimation Rhinorrhea
118
COWS severity scale
0-4 none 5-12 mild 13-24 MODERATE 25-35 moderate/severe >36 severe
119
It is best to give Buprenorphine or Suboxone (buprenorphine/ naloxone) when the patient is in a state of
Moderate withdrawal
120
Antabuse (disulfiram) should not be administered until the patient has been alcohol free for at least
12 hours
121
Patients should refrain from using anything containing alcohol (Vinegar, aftershave, perfume, mouthwash, cough medication) for how long after discontinuing disulfiram
2 weeks
122
The normal value for a mini mental status exam is
25-30 Normal 24-21 Mild dementia 20-10 Moderate dementia 9-0 Severe dementia
123
The normal value for the HAM-D depression rating scale is
(0-27) 0-7 normal 8-13 mild depression 14-18 moderate depression 19-22 severe depression 23-27 very severe depression
124
The normal value for the PHQ-7 depression rating scale is
(0-27) 0 - 4 Normal 5 - 9 Mild 10 - 14 Moderate 15 - 19 Moderated to severe 20 - 27 Severe
125
A normal value for the HAM-A anxiety rating scale is a less than
HAM A (0 - 56) 0 -17 Mild anxiety 18 - 24 Moderate anxiety 25 - 56 Severe anxiety
126
A normal score for the GAD Anziety rating scale is
GAD (0 -23) 0 - 4 Normal 5 - 9 Mild 10 - 14 Moderate 15 - 21 Severe
127
A normal value for the Beck Depression rating scale is
Beck (0-63) 0 - 9 Normal 10 - 18 Mild 19- 29 Moderate 30- 63 Severe
128
What is the acronym used to guide treatment for the brief intervention for treatment of alcohol 
FRAMES Feedback Responsibility Advice Menu Empathetic interviewing Self efficacy
129
What is the most commonly used screening tool for alcohol abuse
CAGE Item responses on the CAGE are scored 0 or 1, with a higher score an indication of alcohol problems. A total score of 2 or greater is considered clinically significant
130
What does the CAGE acronym stand for
Felt the need to (cut down) (Annoyed) by you mentioning your drinking Felt (guilty) about your drinking Felt the need to drink first thing in the morning to steady your nerves (Eye-opener)
131
Delirium is characterized by
Short term changes in cognition Disturbances of consciousness Inattention
132
Delirium has a poor prognosis and
A one-year mortality rate of 40%
133
The Pharmacological treatment of choice For delirium is
Haldol Haldol is preferred for agitated patients Avoid benzodiazepines unless alcohol withdrawal is involved
134
What are the two types of dementia
Cortical and sub cortical
135
Describe cortical dementia
Affecting the outer layer of the brain (Cortex) Which plays a critical role in memory and language Examples include Crutchfield Jacobs, Picks, and Alzheimer’s dementias
136
What symptoms characterize cortical dementia
Severe memory impairments and aphasia
137
Describe subcortical dementia
The early symptoms of clumsiness (MOTOR), irritability, and depression are what differentiates subcortical dementia from cortical dementia Examples include Huntington’s, Parkinson’s, vascular, Lewy body, and AIDS dementia In the later stages both types of dementia have similar presentations
138
Alzheimer’s dementia
without focal neurological deficits
139
Vascular dementia
Diffuse cerebral atrophy and enlarged ventricles Decreased acetylcholine and norepinephrine Carotid bruit, funduscopic abnormalities, and enlarged cardiac chambers
140
HIV dementia
Early signs are motor abnormalities (coordination, tremors, dystonia), cognitive decline, and Behavioral abnormalities
141
Picks dementia (aka frontotemporal dementia or frontal dementia)
language changes (slurred speech)
142
Huntington’s dementia
A high incidence of depression and psychosis
143
Lewy body dementia
visual hallucinations
144
Commonly used standardized instruments for assessing level of impairment in dementia
Montreal cognitive assessment (MoCA) Mini-Cog St. Louis University mental status examination (SLUMS)
145
What are the preferred treatment for psychosis and agitation in dementia
Try non-pharmacological treatments first Atypical antipsychotics are considered first line treatment Benzodiazepines should be avoided as these patients are susceptible to their adverse effects (falls, sedation, and delirium)
146
The goal of primary prevention is to, then name examples
Decrease the incidence of new cases PREVENTION Examples include stress management classes, smoking prevention, drug abuse prevention classes
147
The goal of secondary prevention is to, then name examples
Decrease the prevalence of existing cases Examples include SCREENING, hotlines, crisis intervention, disaster response
148
The goal of tertiary prevention, and provide examples
Decrease the disability and severity of existing cases Examples include REHABILITATION
149
What is kindling
The process of neuronal membrane threshold sensitivity dysfunction Process through which increasingly low severity stimuli can activate negative responses over time. (Seizures)
150
Define addiction
A cluster of cognitive, behavioral, and physiological symptoms indicating that the patient continues to use substances despite significant substance related problems
151
Potency is defined as
The relative dose require to achieve certain effects
152
ADHD requires how many attention symptoms and how many hyperactive symptoms
Six or more symptoms of an attention and six or more symptoms of hyperactivity
153
What are the symptoms of inattention In ADHD
Lack of attention to detail Inability to maintain attention Poor listening skills No follow through Disorganization Avoids hard tasks Loses things Distracted Forgetful
154
What are the Symptoms of hyperactivity in ADHD
Fidgety Inability to stay in seat Running and climbing Inability to engage in quiet activities Always on the go Excessive talking Blurting out information Difficulty waiting for turn Interrupting others
155
There are three types of ADHD what are they
ADHD, inattentive type (Lack of Symptom criteria for hyperactivity) ADHD, hyperactive type (Lack of Symptom criteria for an attention) ADHD combined type (All criteria for hyperactivity and inattention are met)
156
What is the etiology for ADHD
Abnormalities of frontal sub cortical pathways (Frontal cortex, basal ganglia, reticular activating system) Basal ganglia (Motor control) Reticular activating system (Arousal, sleep wake cycle, ability to focus)4
157
What are the neurotransmitter abnormalities affecting ADHD
dopamine dysfunction Norepinephrine dysfunction Serotonin dysfunction
158
Pharmacological management of ADHD
Before starting stimulants assess cardiac history AMPHETAMINES (Adderall) can be prescribed in children ages THREE and older Methylphenidate (Ritalin, Concerta) and Amphetamines can be prescribed in children’s ages six and older Alpha-2 agonist (Non-stimulants- Guanfacine, clonidine, Atomoxetine (Strattera)) Can be prescribed to children ages six and greater
159
In order to diagnose ADHD in children what must be determined
Intellectual functioning based on psychometric testing Psychometric testing: Connor’s parent and teacher reading skills Vanderbilt ADHD diagnostic parent and teacher rating skills
160
What are signs of stimulant abuse
Insomnia Tremors Hypertension and tachycardia Palpitations
161
What does non-pharmacological management of ADHD include
Behavioral therapy Patient and parent cognitive behavioral training program Psychoeducation Treatment of learning disorders  Family therapy and education
162
Describe autism spectrum disorder
Persistent deficits in social communication and social interaction across multiple settings
163
Characteristics of borderline personality disorder
Impulsivity, often with self damaging behavior Recurrent suicidal behavior
164
Non-pharmacological treatment for borderline personality disorder
dialectical behavioral therapy
165
Characteristics of antisocial personality disorder
Reckless disregard for the welfare of others Lack of remorse and indifference to the feelings of others
166
Rett Syndrome occurs primarily in who and what are common physical findings
Girls Common physical findings are loss of purpose for hand skills stereotypic hand movements Deceleration in head growth really look like shit
167
Disruptive mood dysregulation disorder (DMDD) Is characterized by
Diagnosed in children older than age 6 but younger than age 18  Chronic diss regulated mood Frequent temper outbursts and tantrums Severe irritability and anger
168
Pharmacological management of major disruptive mood disorder includes
Atypical antipsychotics Stimulants (for irritability) Antidepressants Mood stabilizers
169
What is the pneumonic for diagnosing depression
SIGE CAPS Sleep disturbance Interest reduced Guilt or self blame Energy loss or fatigue Concentration Diminished Appetite Diminished Psycho motor Changes Suicide Ideation
170
Pharmacological management of major depressive disorder includes educating the patient about
The therapeutic effect of Antidepressant treatment may take 4 to 6 weeks Once antidepressants have been started continue them for minimum of 6 to 12 months If a client has more than two prior episodes of major depressive disorder consider continuing antidepressants indefinitely
171
Tricyclic antidepressants should be avoided in patients with a known history or Family history of
Cardiac dysrhythmias TCAs are known to cause EKG changes and cardiac dysrhythmias
172
If a patient With major depressive disorder is experiencing treatment resistance or psychotic features Watch alternative treatment should be considered
Electroconvulsive therapy
173
What are possible contraindications for electroconvulsive therapy
Cardiac disease Compromise pulmonary status History of brain injury or brain tumor Complications with anesthesia
174
What are some possible adverse effects When treating patients with electroconvulsive therapy
Possible cardiovascular effects Systemic effects (Headache, myalgia, drowsiness) Cognitive effects (memory disturbance, confusion)
175
When treating children, adolescence, or young adults with antidepressants, what should you practitioner always take into consideration
All antidepressants carry a black box warning about increased suicidal thoughts. Patients should be monitored closely for suicidal thoughts/behavior
176
What is a symptom of major depressive disorder that is commonly confused with dementia related symptoms
Cognition and memory loss
177
How can the practitioner differentiate between cognitive and memory loss symptoms in patients with major depressive disorder versus patients with dementia
Clients with dementia usually have a pre-morbid history of slowly declining cognition In major depressive disorder cognitive changes have a relatively acute onset
178
No harm contracts are generally considered
Ineffective at reducing the risk/rate of suicide There is insufficient evidence to prove no harm contracts work
179
What characteristic of fluoxetine (Prozac) Provides the greatest degree of safety for patients who have severe depression
Les potential for injury with intentional overdose
180
The pneumonic for mania in bipolar disorder is
DIG FAST distractibility Impulsivity Grandiosity Flight of ideas (Racing thoughts) Agitation (Psycho motor) Sleep (Decreased) Talkativeness (Pressured speech) 
181
The neurotransmitters involved in bipolar disorder are
GABA, Glutamate, serotonin, norepinephrine, dopamine 
182
An added benefit of using lithium to treat bipolar disorder is that lithium is considered
Neuro protective
183
Which combination medication is FTA approved for the treatment of bipolar disorder
Symbyax (Prozac and Zyprexa)
184
According to the most recent treatment guidelines for bipolar disorder type one with psychotic features the best pharmacologic treatment choice would be an
Antipsychotic To stabilize the patient faster
185
Aside from the obvious symptoms of Steven Johnson syndrome (Tongue swelling, papules, rash, skin sloughing, painful mucous membranes) another important symptom to remember is
Fever
186
Non-pharmacological management of bipolar disorder includes
CBT Behavioral therapy’s Interpersonal therapy’s Supportive groups Milieu therapy
187
What are normal free thyroxine (FT4) lab values
0.8-2.8 ng/dl
188
What are normal thyroid stimulating hormone lab values
0.5 - 5.0 mU/l
189
When T4 and T3 are high, TSH secretion is
Decreased
190
T3 and T4 are low, TSH secretion
Increases
191
Hypothyroidism is defined as
Increased TSH (Decreased T4 and T3)
192
Systemic effects of hypothyroidism include
Cold intolerance Confusion Decreased libido Weight gain
193
Hyperthyroidism is defined as
Decreased TSH (Increased T3 and T4)
194
Systemic effects of hyperthyroidism include
Heat intolerance Irritability Agitation Anxiety Tachycardia Mood swings Weight loss
195
ALT (Alanine aminotransferase) Normal lab values are
5 to 35 U/l
196
When liver damage occurs serum ALT levels rise as much as
50 times normal
197
Commonly seen laboratory findings in patients with alcohol dependence and abuse
AST/ALT ratio of >2.0 Elevated: Glutamyltransferase Mean corpuscular volume Prothrombin time Uric acid Total cholesterol Triglycerides Decreased: Magnesium Calcium Potassium BUN H&H Platelet Albumin
198
Oppositional defiant disorder is characterized by what two symptoms
An enduring pattern of angry or irritable mood and argumentative, defiant, or vindictive behavior lasting at least 6 months with at least four of the associated symptoms Argues with authority Absence of physical aggression 
199
How is oppositional defiant disorder managed
Non-pharmacologically Individual Therapy family therapy (emphasis on child management skills), teaching parents about positive reinforcement and boundary settings. Evidence based treatment : Child and parent problem-solving skills (Adolescent Transitions Program ATP)
200
What are the defining characteristics of conduct disorder
Lack of remorse Aggression to people or animals The rights of others or societal norms or rules are violated
201
What is the pharmacological management of conduct disorder
Target mood and aggression Aggression and agitation are treated with antipsychotics, mood stabilizers, SSRI, and alpha agonists
202
Which symptoms are characteristic of conversion disorder
NEUROLOGICAL symptoms that cannot be explained by medical condition Mutism Blindness Paralysis Paresthesia (Glove stocking syndrome)  Symptoms usually begin suddenly after a stressful event
203
Which symptoms are characteristic of adjustment disorder
EMOTIONAL or behavioral reaction to a stressful situation An unhealthy reaction/response to an event that occurs within three months of it happening Example: Stressful events or changes in the life of your child or adolescent may be a family move, the parents' divorce or separation, the loss of a pet, or the birth of a sibling.
204
What are the subtypes types of adjustment disorder
Adjustment disorder with depressed mood Adjustment disorder with anxiety Adjustment disorder with mixed depression and anxiety Adjustment disorder with Disturbance of conduct Adjustment disorder with mixed emotions and conduct (A combination of all the above disorders)
205
In the absence of other significant clinical symptoms, grief is usually classified as
Adjustment disorder
206
Post traumatic stress disorder is best described as
Re-experiencing of an extremely traumatic event accompanied by symptoms of increased arousal and avoidance of stimuli associated with the trauma
207
Off label pharmacological management of nightmares may include
alpha antagonist like prazosin
208
What is the inclusion criteria for Tourette’s syndrome
At least 2 motor tics and at least 1 vocal (phonic) tic have been present, not necessarily at the same time Tics are not caused by the use of a substance or other medical condition.
209
What is the primary neurotransmitter involved in Tourette’s syndrome
dopamine Serotonin Norepinephrine
210
A common medication used in the treatment of Tourette’s syndrome is
Haldol (D1 and D2 antagonist) because of the excessive levels of dopamine Also Aripiprazole
211
What is the only known antipsychotic that has been shown to reduce the risk of suicide In patients diagnosed with schizophrenia
Clozaril
212
Most second generation antipsychotics (Clozapine, olanzapine, Quetiapine, and risperadone) cause the undesirable side effect of
Weight gain Ziprasidone (Geodon), aripiprazole (abilify), and lurasidone (latuda) are weight neutral. aripiprazole (least sedating)
213
What is the etiology of schizophrenia
Inadequate synapse formation Excessive pruning of synapses Excitotoxic death of neurons Prenatal exposure to toxins, including viral agents
214
What are some common in neurobiological findings in patients with schizophrenia
Enlarged ventricles Smaller frontal and temporal lobes Cortical atrophy Decreased cerebral blood flow Smaller hippocampus and amygdala
215
What are the characteristic neurotransmitter concentrations in schizophrenia
Excessive dopamine in mesolimbic pathway Decreased dopamine in the nasal cortical pathway Excessive glutamate Decreased gaba Decreased serotonin
216
What is the average ave age of onset of Symptoms of schizophrenia in men
18 to 25 Men tend to have more negative symptoms
217
What is the average age of onset forsymptoms of schizophrenia in women
Age is 25 to 35 Women usually experience more dysphoria than men and tend to have paranoid delusions and more hallucinations than men
218
Atypical antipsychotics are effective at managing symptoms of schizophrenia because of your action on which receptors
D2 and 5HT2A And have less EPS
219
What are the positive symptoms of schizophrenia and what is the cause
Hallucinations Delusions Referential thinking Disorganized behavior Hostility Grandiosity Mania Suspiciousness Caused by excessive dopamine in the mesolimbic pathway
220
What are the negative symptoms of Schizophrenia and what is the cause?
The “A’s” Affect (Flattened) Alogia (Poverty of speech) Avolition Apathy Abstract thinking (Inability) Anhedonia Attention deficit The cause is decreased dopamine in the mesocortical pathway
221
What Is a non-pharmacologic method of treatment for patients with schizophrenia
ACT (Assertive community treatment) An evidence based, multidisciplinary team approach which is available to patient with schizophrenia living in the community. This is an alternative to restrictive residential or hospital settings
222
Which aspects of preventative care should be considered during follow up with patients with schizophrenia
In order to screen for complications of treatment practitioners should monitor: serum glucose lipid panels Weight BMI Waist to hip ratio
223
 How many stages of human development are there according to Erikson? What are they?
eight Infancy 0-1 Early childhood 1-3 LATE CHILDHOOD 3-6 SCHOOL-AGE 6-12 Adolescence 12-20 Early adulthood 20-35 Middle adulthood 35-65 Late adulthood >65
224
What is the developmental task of infancy according to Erikson
Infancy 0 to 1 year Trust versus mistrust
225
What is a developmental task of early childhood according to Erikson
Early childhood 1 to 3 years Autonomy versus shame and doubt
226
What is the developmental task of late childhood according to Erikson
LATE CHILDHOOD 3 to 6 years INITIATIVE v GUILT
227
What is the developmental task of school age according to Erickson
SCHOOL AGE 6 to 12 years INDUSTRY v INFERIORITY
228
What is the developmental task of adolescence according to Erikson
Adolescence 12 to 20 years Identity versus role confusion
229
What is the developmental task in early adulthood according to Erikson
Early adulthood 20 to 35 years Intimacy versus isolation
230
What is the developmental task of middle adulthood according to Erikson
Middle adulthood 35 to 65 years Generativity versus self absorption (Stagnation)
231
What is the developmental task in late adulthood according to Erikson
Late adulthood greater than 65 years Integrity versus despair
232
What are indications of developmental mastery in late childhood according to Erikson
Self directed behavior, Ability to be a self starter Purpose
233
What is an indication of developmental mastery in school age children according to Erikson
Competency Friends and classmates play a role in how children progress Through proficiency at play and schoolwork, children are able to develop a sense of competency and pride in their own ability
234
How many stages of cognitive development are there according to Piaget. What are they called?
Sensorimotor (0-2) Object permanence PREOPERATIONAL (2-7) Egocentric, Magical thinking (Believe their thoughts can influence their environment) Concrete operational (7-12) Reversibility and conservation FORMAL OPERATIONAL (>12) ability to think abstractly, thinking operates in a formal, logical manner
235
Define object permanence
Objects continue to exist after they are no longer seen
236
Define object constant y
Absence does not mean disappearance or abandonment
237
Describe the phallic stage of Freud’s psychosexual stages of development
Occurs ages 3-6 Exhibition, masturbation with focus on oedipal conflict, anxiety of castration males in fear of lost maternal love in females Can lead to sexual identity disorders if failure to fulfill stage
238
Idealization is it coping method for dealing with
Anxiety
239
What are two key themes used in motivational learning
Affirm the patient’s positive treats Reflective listening Being non-confrontational and non-adversarial
240
What are the 5 predictable stages of change that occur according to the trans theoretical model of change
Precontemplation: Not aware of the problem. Practitioner should raise the patient’s awareness without giving any prescriptive advice Contemplation: Aware of a problem but not committing to change. The practitioner should help the patient see the benefits of change and the consequences of not changing, Preparation: The patient has made the decision to change. The practitioner should help the patient find a change strategy Action: The patient is engaging in overt actions to change. The practitioner should support and advocate for patient Maintenance: The patient is engaging in behaviors to prevent relapse. The practitioner should help the patient identify the possibility of relapse and identify and use strategies to avoid relapse
241
Who developed cognitive therapy and what is the goal
Cognitive therapy was developed by Aaron Beck The goal is to change clients irrational beliefs, faulty conceptions, and negative cognitive distortions
242
What techniques does behavioral therapy employ to help change patient’s maladaptive behaviors
Modeling Exposure Relaxation Problem-solving Role-playing 
243
What is the aim of cognitive behavioral therapy
Change the patient’s thought patterns, conscious and unconscious beliefs, Attitudes, and behavior to increase their ability to attain goals and face face difficulties
244
How does cognitive behavioral therapy work
The patient and Therapist work as a team to identify problems, devise strategies, and create solutions (SKILLS TRAINING AND EXPOSURE)
245
Some essential cognitive behavioral therapy tools are
JOURNALING COGNITIVE RESTRUCTURING  (Exploring the cause of Faulty thinking, and then restructuring and reframing them Nightmare exposure Relaxed breathing Unraveling cognitive distortions Exposure and response prevention
246
PANDAS is
(Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections) Sudden onset of OCD symptoms associated with streptococcal infection
247
Existential therapy is aimed at
Understanding the patient subjective experience
248
Existential therapy emphasizes
Making responsible choices and excepting freedom Understanding the patient’s subjective world/experiences
249
Goals of existential therapy are to
Focus on the present and on personal responsibility Understand the patient’s subjective world/experiences
250
Existential therapy is suited for
Terminal illness, suicidal thoughts
251
Humanistic therapy is also known as known as
Person centered therapy
252
Humanistic therapy involves the concept of
People are born with the capacity for: Self-directed growth Self actualization
253
What is the goal of interpersonal therapy
identify and modify interpersonal problems to manage relationships
254
Which psychiatric disorder is EMDR most commonly used in
PTSD Although both CBT and EMDR are used in PTSD, EMDR is preferred
255
What is the goal of EMDR
To achieve adaptive resolution
256
What are the three phases of EMDR
Desensitization phase Installation phase Body Scan
257
What does the desensitization phase of EMDR involve
Client visualizes the trauma and verbalizes the negative thoughts or maladaptive beliefs are remaining attentive to physical sensations. This process occurs for a limited time While the client maintains rhythmic eye movements The client is then instructed to block out negative thoughts and to verbalize their feelings
258
What does the installation phase of EMDRinvolve
The patient installs it increases positive thoughts that they have declared as a replacement of the original negative thought
259
What does the body scan phase of EMDR involve
The client Visualize the trauma along with a positive thought and then scans their body mentally to identify any tension
260
Irving alone was the first person to
What is the reticle perspective on group work and identified 10 therapeutic factors unique to Group Therapy
261
What are the unique factors of group therapy as defined by Irving Yalom
Installation of hope Universality Altruism Increase development of socialization skills Imitated behaviors Interpersonal learning Group cohesiveness Catharsis Existential factors Corrective refocusing
262
What is the focus of family systems therapy
Focus is on chronic anxiety within families Uses genomes and triangles
263
What are the treatment goals of family systems therapy
To increase levels of self differentiation And awareness of each members function within a family
264
What are triangles within family systems therapy
Dyads that form triads to decrease stress The lower the level of family adaptation the more likely a triangle will develop
265
Structural family therapy examines
The boundaries and hierarchy within a family
266
What is the difference between strategic Family therapy and structural family therapy
Strategic Family therapy is more symptom focused than structural family therapy
267
What is a paradoxical directive within strategic therapy
A paradoxical directive is a negative Task that is assigned to a family member who is resistant to change (use with caution)
268
Solution focused therapy utilizes
Miracle questions ” If a miracle water happen tonight while you were asleep and tomorrow morning you a walk to find the problem no longer existed, what would be different?” “ How would you know the miracle to place?” “ How would others know?”
269
Which complementary/alternative therapy is used to treat pain and depression
Acupuncture
270
List the 11 defense mechanisms
Denial Projection Regression Repression Reaction formation RATIONALIZATION Undoing INTELLECTUALIZATION Suppression Sublimation Altruism
271
The defense mechanism of projection is best described as
Individuals attributing their own unacceptable thoughts and feelings to another person. “ Do you hate someone but you know this is an unacceptable emotion so you ‘solve’ the problem by believing they hat you”
272
A defense mechanism of displacement is best described as
redirection of an impulse (usually aggression) Onto a powerless substitute target
273
The defense mechanism of sublimation is best described as
 Displacement of unacceptable emotions into behaviors which are constructive and socially acceptable
274
The defense mechanism of INTELLECTUALIZATION Is best described as
Concentrating on the intellectual aspects of a situation to avoid emotional aspects
275
The defense mechanism of RATIONALIZATION is best described as 
An attempt to logically justify an unacceptable behavior
276
Research has shown a correlation between ACE adverse childhood experiences (Traumatic events occurring between the ages of zero and 17) and
Heart disease, fractures, diabetes, unintentional pregnancy, depression, anxiety, COPD, Chronic bronchitis, sleep disorders, Dissociative disorders, Eating disorders, alcoholism
277
When working with avoidant patients with the history of trauma what communication techniques are effective/helpful
Communication techniques that increase arousal Activation of the amygdala is needed so that memories stored there can be re-processed
278
How is the recovery model defined
There is an emphasis on resilience and control over problems Rather than full symptom resolution
279
Recovery as defined by the recovery model is
Not about getting rid of problems for a rather fostering ones own Abilities, interests, dreams
280
Recovery as defined by the recovery model is a process which is
Non-linear With occasional setbacks and learning from experience
281
The four dimensions of recovery according to the recovery model are
 Health  Home Purpose Community
282
Alternative community treatment Is centered on
The patients Personal strengths, and needs, and desires for the future It serves as an alternative to more restrictive Residential or hospital settings for patients with more severe mental illness
283
Tics are contraindicated for what classification of medication
Stimulants Use guanfacine instead
284
The priority item after being notified by a patient at a have been raped or abused is to
Assure them that they are safe
285
The best setting to preform a psychiatric exam/interview on a patient is
In a private office or private area with the door open or partially open
286
If a child comes to your office with their parents and says that they were abused, make sure to
Interview the patients separately Notify CPS
287
If a child is playing with a toy in a sexual way during your interview then you should be suspicious of
Sexual abuse Immediately notify CPS
288
Therapeutic alliance is built with adolescents by reassuring them that
Information is confidential Interview them without parents in the room
289
If a patient has a repeated history of self harm or suicidal ideations it’s important to notify them during your first meeting
About the limits of confidentiality
290
It Create an ethical dilemma to separate parents from children for the purpose of interviewing them However,
You must advocate for your patient (In this case the child) who has the right to confidentiality
291
When taking this exam
Inter-collaboration is encouraged and delegation is often incorrect
292
You have identified a gap in care when OB patients are discharged without Risk assessment for postpartum depression. You Work in conjunction with your coworkers to Create andimplement a screening process. In this scenario you have
Identified a problem and collaborated to find a solution
293
During this exam referring out should always be considered
As a last option. Ensure that there’s nothing else you can do for your patient before referring out. This may include lab work, counseling, testing etc.
294
When considering symptoms of a mental health disorder within a cultural context, ensure that you have the patient
Contextualize their symptoms with regards to their culture. Just because the patient appears to have symptoms of mental illness does not mean that they have a diagnosable mental illness.  You can offer them a brief supportive therapy
295
If a patient has lost a job or house appropriate intervention would be
Brief supportive therapy not medication
296
When attempting to reduce Mental health stigma within a diverse community the practitioner must use
Multicultural teaching Ethnospecific assessment parameters
297
Common belief among Native Americans is the mental illness and or substance use disorder can be caused by
An imbalance between individuals in the world
298
The ethnic group with the highest rate of suicide and suicide attempts in the US is
Native Americans
299
If an employee of your office is attempting to take away a healing stick from a patient and the best action is to
Teach the employee about cultural competency and sensitivity
300
If a patient wants you to release information to their traditional healer you must first
Obtain clearance for informed consent from the patient
301
Normal TSH values are
0.5 - 5.0
302
If your patient taking depakote presents with signs of a heptaotoxicity (abdominal pain in the upper right portion of abdomen, reddish brown urine, jaundice, fatigue) Your next action should be to
To a liver function test checking me AST and ALT levels
303
Normal AST levels
5-40
304
Normal ALT levels
5-35
305
What is the therapeutic range for valproic acid
50 a 125
306
What are toxic levels for valproic acid
>150
307
What are signs of valproic acid toxicity
Disorientation Lethargy Respiratory depression Nausea/vomiting
308
What should be your next action if your patient presents with valproic acid toxicity
Stop valproic acid Check valproic acid level Check LFT and ammonia level
309
Kava is
An herbal supplement used for anxiety, stress, insomnia
310
Kava can cause
Liver damage
311
Kava interacts with
Xanax (can cause excessive drowsiness) CNS depressants (Can cause excessive drowsiness)
312
Lamictal (lamotrigine) Has a black box warning for
Steven Johnson syndrome (FEVER, Bodyaches, rash, peeling skin, tongue swelling)
313
Which mood stabilizer is the least likely causes weight gain
Lamictal (lamotrigine) Also the least likely chance of causing metabolic syndrome
314
Which antipsychotics cause the least weight gain?
Ziprasidone Aripiprazole Lurasidone
315
Which antipsychotic is the least sedating
Aripiprazole
316
How should the practitioner manage antipsychotic induced weight gain
Primary action should be nonpharmacological strategies to include exercise and nutritional counseling If primary action unsuccessful, pharmacological interventions consist of switching to another antipsychotic with less potential for a weight gain Ziprasidone (Geodon) Aripiprazole (abilify) Lurasidone (latuda)
317
The signs of infection caused by agranulocytosis in patients taking carbamazepine or Clozaril are
Sudden fever Chills Sore throat Weakness
318
If a lithium level is greater than 1.4 in the practitioner must
Discontinue lithium regardless of symptoms and signs of toxicity
319
If a lithium level is 1.3 or 1.4 the practitioner may
Continue to Prescribe with him while monitoring the patient for signs and symptoms of toxicity
320
The neuroprotective treatment of choice for bipolar disorder is
Lithium
321
The only known Antipsychotic medication that has shown to reduce the risk of suicide in patients diagnosed with schizophrenia is
Clozaril 
322
ACE inhibitors (lisinopril) NSAIDs (ibuprofen, indocin), and thiazides (hydrochlorothiazide) can reduce
Renal clearance and cause lithium toxicity
323
Patients who are taking Lithium should be encouraged to
Increase their fluid intake to avoid dehydration
324
What should be the practitioners intervention if they suspect lithium toxicity
Discontinue lithium Check Serum lithium levels
325
A washout time of how many half-lives is recommended between cessation of the previous drug and the introduction a new drug to avoid serotonin syndrome
5
326
When treating cancer patients experiencing depression medication’s with the least chance of drug drug interactions are
Citalopram (celexa) and escitalopram (lexapro) both are SSRIs
327
For patients with chronic neuropathic pain who are experiencing depression the best choice of antidepressant is
an SNRI Cymbalta (Duloxetine) Effexor (venlafaxine)
328
What classification of medication is used for chronic neuropathic pain
Alpha-2 Delta Ligands Lyrics (Pre-Gabalin) Gabapentin 
329
Which classification of antidepressants has the lowest incidence of sexual dysfunction side effects
NDRIs Bupropion (Wellbutrin) Both SSRIs and SNRIs can both cause sexual side effects
330
Which classification of antidepressants will help depressed patients were also experiencing fatigue
Bupropion (Wellbutrin) which is in an NDRI
331
Bupropion (Wellbutrin) is know to increase risk of 
Seizure
332
For children and adolescents taking SSRIs and SNRIs what should be assessed with each visit
Frequency and severity of self harm
333
Which SSRI can cause insomnia and should be taken in the morning
Prozac (Fluoxetine)
334
If a patient is self-medicating with alcohol it is considered
A barrier to treatment
335
Which mental health disorders are known to increase thoughts of self harm
Depression Bipolar disorder Alcohol abuse Eating disorders Schizophrenia
336
Which personality disorder is most likely to present with homicidal ideation
Antisocial personality disorder
337
Few experimental studies exist and investigate the placebo effect of antidepressants in
Children and adolescents When compared to adults, children with depression have a reduced placebo rate. This is because few parents want their children to receive placebos instead of standard of care
338
Which areas of the brain can cause aggression, impulsivity, and abstract thinking problems in patients with schizophrenia
Abnormality in the prefrontal cortex, amygdala, basal ganglia, hippocampus, and limbic regions of the brain
339
Patients with schizophrenia have low tolerance to
ALPHA 2 ADRENERGIC RECEPTOR AGONIST like (GUANFACINE AND CLONIDINE) The NEUROPTOTECTIVE EFFECTS of these medications are limited ARE LIMITED
340
Stimulants potentially the release of which neurotransmitter
Dopamine
341
Prescribing stimulants to patients with schizophrenia can cause an increase in which symptoms and why?
Stimulants can cause an increase in positive symptoms because of increased levels of dopamine in the mesolimbic system
342
 A patient with a long-term history of medication not adherence would benefit from
A Case Manager who could arrange for a nurse to go to the patient’s home to administer their medication
343
What are the benefits of exercise programs for patients with schizophrenia
Exercise can improve cognition, quality of life, and long-term health
344
If patients with schizophrenia are the higher risk for relapse sometimes they are switched from oral to intramuscular Haldol. What is the ratio and what is the maximum dose intramuscularly per visit?
20 x’s the daily dose for the first month 15-10 x’s the daily dose for every month after the first The patient should receive no more than 100 mg intramuscular per visit. They can return after 5 to 7 days to receive the rest of the dose if it exceeds 100mg
345
Define delusion
I firmly maintained belief despite information to the contrary
346
When performing a mental status examination of a preschool child (3-5), Information is obtained primarily through
CLINICAL OBSERVATION by listening and observing cues
347
The MMSE (Folstein scale) defines Recall as
Memory Ask the patient if they can recall the three words you previously asked them to remember
348
Can the min mental status exam be used in pediatric patients 
No
349
Which atypical antipsychotic can be given intramuscularly for rapid stabilization of psychosis
Ziprasidone (Geodon) Aripiprazole (abilify) Paliperidone (Invega) 
350
Dystonia is caused by and characterized by
D2 receptor blockade in the nigrostriatal dopamine pathway Painful muscle spasms in the neck, stiff neck 
351
Increased Acetylcholine levels can cause
Increased salivation, watery eyes, diarrhea
352
Reglan can cause
EPS (Tardive dyskinesia, Parkinsonism)
353
Which two neurotransmitters are affected when a patient is experiencing extraparametal symptoms
Dopamine is decreased by the antipsychotics and acetylcholine is increased. There is an inverse relationship between dopamine and acetyl choline
354
What are normal prolactin levels in men and women
Men <20 Women <25
355
If a patient who is taking olanzapine (Zyprexa) Tells you that they have begun smoking what should you do
Increase the patient’s dose of olanzapine Tobacco is an inducer And will decrease the serum levels of olanzapine
356
If a patient who is taking olanzapine tells you that they have quit smoking you should
Decrease their dose of olanzapine. Tobacco was acting as an inducer thereby increasing the metabolism of olanzapine. With the tobacco no longer present serum olanzapine levels will increase
357
Which classification of medication is associated with mania, depression, and psychosis
Steroids
358
If a patient who is taking antidepressants or mood stabilizers begins a medication that can cause depression or mania,what should the practitioner do
Increase the dose of either the antidepressant or a mood stabilizer to counteract the potential symptoms of depression or mania
359
Which to neurotransmitters are involved in addiction
Dopamine and GABA
360
If a patient with anorexia complains of pain after eating which diagnosis should the practitioner consider
Delayed gastric emptying
361
Are which medication can delay gastric emptying
Ranitidine Omeprazole Famotidine 
362
Which classification of medication can decrease the absorption of psychotropic medication’s
Proton pump inhibitor antacids
363
Which symptom should be closely monitored in older adults (>65) who are taking SSRIs
Anxiety
364
If a medication causes a paradoxical effect the practitioner would want to
Avoid prescribing the medication future
365
Ziprasidone (geodon) can cause 
QT prolongation
366
The FDA now warrants that citalopram should don’t be given and doses greatest and 40mg daily (>20mg/daily in older adults) because
Doses over 40 mg can cause prolongation of the QT interval and lead to an abnormal heart rhythm (including torsade de pointes)
367
Apoptosis is defined as
Neuronal loss and cell death
368
The greatest risk for developing symptoms of bipolar disorder is
Family history (Highly inherited)
369
When diagnosed after the age of 45, bipolar disorder is almost always associated with
A medical condition
370
If a patient with borderline PD presents with irritability, anger, and self-harming behavior, The Practitioner should consider prescribing
lithium
371
If a patient with borderline PD presents with depressed mood, emotional lability, interpersonal problems, rejection sensitivity, aggression, and hostility
The practitioner should consider prescribing Depakote
372
If a patient presents with borderline personality disorder exhibiting symptoms of self harm and suicidality then the therapy of choice is
Dialectical behavioral therapy because it has evidence of decreased suicidality in patients with borderline personality disorder
373
What are two techniques used in the process of diagnosing a patient with borderline personality disorder
Journaling and diary 
374
Which medications can help control the behavioral symptoms such as impulse control problems and rage in Tourette’s syndrome
clonidine (Catapres, Kapvay) and guanfacine (Intuniv)
375
Acute stress disorder is
A psychiatric diagnosis that may occur in patients within 4 weeks of a trauma Versus posttraumatic stress disorder in which symptoms manifest >four weeks after the event
376
What is the eitology of ADHD inattentive type
Abnormalities in the prefrontal cortex
377
What part of the frontal cortex is specifically involved in executive function
Dorsolateral prefrontal cortex
378
If a patient’s parents were to become anxious during psychoeducation regarding ADHD the providers first action would be to
Stop and provide support to the parents
379
The symptoms most characteristic of obsessive compulsive disorder OCD or
Recurrent and persistent thoughts, impulses, images, compulsions (example motor tics) Neurotransmitters affected are serotonin and norepinephrine
380
Distinguishing characteristic between obsessive compulsive disorder Tourette’s disorder is
The absence of Intrusive and persistent thoughts with Tourette’s disorder (tics only) The presence of Intrusive thoughts with obsessive compulsive disorder (tics + intrusive/persistent thoughts)
381
What are the definitions of and differences between Factitious disorder and malingering disorder
Factitious disorder is self-induced harm to produce symptoms of illness (No secondary gain) Malingering disorder symptoms are faked to achieve secondary gain.
382
What is the priority action if a child reports factitious disorder by other
Immediately report/notify CPS
383
What are the symptoms the most characteristic of reactive attachment disorder
Fearful, inhibited, withdrawn, apathetic, shows no emotion towards caregivers The product of the severely dysfunctional really relationship with caregiver, neglect
384
Two defining characteristics of general anxiety disorder are
Excessive worry for > 6 months
385
To defining characteristics of panic attack are
Abrupt surge of intense fear Impending doom
386
Panic disorder is best described as 
Recurrent unexpected panic attacks
387
The pharmacological treatment of choice for panic disorder or
the SSRIs Paroxetine (paxil), fluoxetine (Prozac), sertraline (Zoloft)
388
Disruptive mood dysregulation disorder is the best defined as
A depressive disorder occurring in children > age 6 but > age 18 These children are severely moody and irritable with frequent intense anger outbursts and temper tantrum’s
389
The ‘Broken Mirror’ theory of Autusm
Dysfunction of the mirror neuron system causes Poor social interaction and cognition
390
Which questionnaire would be most appropriate if the patient is irritable, depressed, with labile mood
Mood disorder questionnaire
391
It is important for the practitioners remember that nightmares in children can be attributed to
A family history or genetic predisposition
392
Which what are three things that should be ruled as possible causes of delirium in an older adult
Vitamin B 12 Folic acid Infection
393
If a patient has pseudo dementia, primary diagnosis is
Depression (With memory and cognition impairment)
394
Compared to dementia, the onset of pseudo dementia is
Acute And associated with depressive symptoms
395
When interviewing a patient with Pseudo dementia a practitioner would expect the answer of
“ I don’t know” vs the lack of an answer or confabulation with dementia
396
Irritability, anger, hallucinations, and delusions can all the symptoms of what in older adults
Depression
397
The primary characteristics that defines cortical dementia from subcortical dementia is
Subcortical dementia involves motor abnormalities (coordination, ataxia, dystonia, tremors) Cortical dementia involves Language in memory impairments (aphasia, amnesia)
398
Preferred treatment for HIV dementia is
Antiretrovirals
399
What area of the brain is involved in speech comprehension
The temporal lobe (Wernicki’s area)
400
What area of the brain is involved with Speech expression
The frontal lobe (Broca’s area)
401
What are considered first-line agents in patients with psychotic symptoms of dementia
Atypical antipsychotics
402
What symptoms would the practitioner expect to see in a patient with a frontal lobe tumor
Personality changes and aggression
403
The substantia nigra helps to regulate
Motor movements
404
Signs of lead poisoning
Developmental delay, learning difficulties, Irritability, Loss of appetite, Weight loss, Sluggishness and fatigue, Abdominal pain, Vomiting, Constipation, hearing loss, Seizures, eating things such as paint chips, that aren't food (pica).
405
How does multisystem family therapy work and who is it targeted for
Youth‘s age is 12 to 17 years who present with serious antisocial, problematic behavior, and with serious criminal offenses The patient’s parents are empowered with resources and skills to help effectively manage their children
406
Multi system family therapy utilizes which types of services
Home based model of service delivery to reduce barriers that keep families from accessing services
407
The most important factor in effective hildhood grieving is
An intact family
408
What are the neurotransmitters involved in mood disorders
GABA, glutamate, dopamine, norepinephrine, serotonin
409
If a member is uncomfortable sharing with the group in the practitioner should
Encourage them to continue attending group And individual sessions for the group member
410
Awareness of body sensations especially breath awareness is a key element of
Mindfulness meditation
411
What exercise can help provide resilience in children
Self-esteem building
412
If a patient is unable to construct a chronological narrative in the provider could assist by using
Closed ended questions
413
If a therapy session is scheduled for a husband and wife and one member cannot be present the Therapist should
Reschedule
414
If a 15-year-old brother sodomizes Their five year old brother, the therapist should insist that
The brother not be left alone with the younger brother Also, the therapist should initiate crisis management
415
What is normal for boys to develop what between the ages of nine and 16 years
Breast buds Usually resolve within six months
416
Therapist should order which lab value for a patient presenting with rheumatoid arthritis
ESR Eosinophil sedimentation rate
417
An increased intercranial pressure can cause an infants cry to sound
Shrill
418
Why are women more likely to become intoxicated as well as Develop alcohol induced liver problems than men
Women produce less alcohol dehydrogenase than men
419
The grasp reflex (Palmer reflex) is normal unit what age
5-6 months
420
The startle reflex (Moro reflex) Is normal up until 
5-6 months
421
The Babinski reflex is normal up until
2 years When the sole of the foot is stroked in an upward motion the toes fan out
422
Phosphodiesterase type 5 (PDE5) ie Cialis/Viagra are
Rapidly absorbed
423
IF a patient presents with NORMOCYTIC MACROCYTIC ANEMIA give which supplements
FOLIC ACID B12 IRON
424
The practitioner should screen all adolescent ADHD patients for
Substance abuse Likewise all adolescence with substance abuse disorder should be screened for ADHD
425
The right of the habius corpus allows patients to
Leave the hospital AMA if they feel like they have been falsely hospitalized
426
Acute disseminated encephalomyelitis (ADEM) is characterized by a brief but widespread attack of inflammation in the brain and spinal cord that damages myelin – the protective covering of nerve fibers. ADEM often follows viral or bacterial infections, Neuro exam findings might include
Asymmetrical movement of the extremities Ataxia Paresthesia Fatigue/weakness/confusion 
427
When attempting to answer your PICOTquestion what is the highest level of evidence (level 1)
Level 1 = A systematic review of all relevant randomized controlled trials
428
PICOT stands for
Problem Intervention Comparison Outcome Time
429
The practitioner can assist a patient who is having difficulty constructing a timeline of their symptoms by
Asking specific questions that will anchor the patient’s memory or link memorable events together
430
Iatrogenic disease/illness is defined as
Tests, surgeries, medications that cause side effects And example would be risperidone causing breast discharge
431
And effective means for convincing employees of implementing a new policy change would be to explain how the new policy will
Improve the quality of patient care
432
For the nurse practitioner functioning in the outpatient setting in effect means for demonstrating continuous quality improvement would be to
Develop an instrument to monitor clinical outcomes
433
For the nurse practitioner working with patients who have depression and anxiety and effective means to assess performance and outcomes would be to implement
standardize rating scale at regular intervals
434
Auto immune diseases can increase levels of what
Cytokines
435
What are some common signs and symptoms of alcohol withdrawal
Tremors Paroxysmal sweal Tactile disturbances Auditory disturbances Visual disturbances Headaches
436
Three Pharmacological treatments of alcohol dependence may include
Acamprosate (Not metabolized in the liver) maintain sobriety By controlling drinking urges and cravings Disulfiram (Antabuse) Naltrexone (vivitrol) blocks the effects and feelings of alcohol. Naltrexone reduces alcohol cravings and the amount of alcohol consumed 
437
Who determines the scope of practice within a given state
Deterrined by State legislative statues (State board of nursing). It defines the nurse practitioners role and varies broadly from state to state
438
Who determines the standards of practice for a nurse practitioners
The American nurses association
439
What are two exceptions to patient confidentiality
Patient discloses intent to harm self or others Answering court orders, subpoenas, or summons
440
Informed consent is defined as
A communication process between provider in patient that results in a patient accepting or refusing the plan of care
441
Desmopressin his medication used for
Enuresis (nighttime bed wetting) Decreases urine production
442
If a new black box warning is issued by the FDA The practitioner should do work before taking patients office medication or putting patient on to the medication
Research the risk and benefits
443
It is important for the Practitioner to do what two things for every medication and treatment they prescribe
Provide the patient with full disclosure Document the disclosure and education
444
Reflective practice is defined as
Using debriefing strategies after an adverse event Process of continual adaptation and learning
445
Name three legal concerns for tele medicine 
Confidentiality Medical errors Jurisdictional authority
446
If a pregnant patient is found to be misusing alcohol, The primary action of the nurse practitioner is two
Refer her to a residential treatment facility (Not report her for using alcohol while pregnant)
447
Example of Nonmaleficence: Doing no harm
Example: Stopping a medication that is causing harmful side effects or discontinuing a treatment strategy that is not effective and may be harmful. Imminent danger.
448
Fidelity is defined as
Being true and loyal. Fidelity, comes from the Latin "fides" meaning faithfulness, is concerned with promise keeping, integrity, and honesty, It also involves meeting the patient's reasonable expectations (role fidelity) such as being respectful, competent, and professional
449
Just culture is defined as
In a just culture, individuals are continually learning, designing safe systems, and managing behavioral choices.
450
The process of continuous quality improvement utilizes which acronym
PDSA Plan Do Study Act
451
Within the four components of health policy who are the policy makers
Process Policy reform Policy environment Policymakers (Stakeholders and key players)
452
To assess barriers and facilitate evidence-based practice, PMHNPs should assess what among health-care providers
assess baseline knowledge, beliefs, and practices among health-care providers using a survey.
453
Defined the case management model
Nurses can optimize client self-care, reduce fragmentation of care, provide quality care across the continuum, improve clients' quality of life, patient care and outcomes, reduce length of hospitalization, increase client, and staff satisfaction, This model allows nurses to demonstrate there strengths as members of the multidisciplinary health care teams.
454
Tarasoff principle holds that providers have a
Tarasoff principle (Tarasoff v. Regents at the University of California, 1976): Duty to warn potential victim of imminent danger of homicidal clients,
455
Donaldson versus Connor determined that
It is unconstitutional to commit person involuntarily who is not immediately a threat to themselves or others
456
Risk factors for suicide
Previous suicide attempt Ages 45 or older if male Ages 55 or older if female Divorced, single, or separated Caucasian
457
Normal T3 values
0.9 to 2.8 nanomoles per liter (nmol/L)
458
The Saint Louis University Mental Status. (SLUMS) Examination for detecting mild cognitive impairment and dementia. What is a normal score
SLUM (0-30) 27 - 30 Normal 21 - 26 Mild 0 - 20 Dementia