Gentamicin Flashcards
1
Q
class of gentamicin
A
aminoglycosides
2
Q
how does gentamicin block protein synthesis
A
bacteriocidal/bacteriostatic. irreversible binding to 30s ribosomal subunit –> misread mRNA
3
Q
resistant aerobic gram -ve bac targeted by gentamicin
A
- enterobacter
- serratia
- klebsiella
4
Q
indications for gentamicin
A
- septicaemia
- meningitis
- nosocomial RTI
- complicated UTI
- intra-abdominal infections
5
Q
contraindications gentamicin
A
- preggo
- myasthenia gravis
6
Q
SEs gentamicin
A
- nephrotoxicity
- ototoxicity (irreversible)
- abx-colitis
7
Q
gentamicin is mostly excreted via
A
urine
