GenSurg Flashcards
Contents: Pancreatitis, Diverticulitis, Appendicitis, Inguinal hernia, Bowel Obstruction, Cholecystitis
What are the most common causes of pancreatitis?
Chronic EtOH & gallstones.
Less common: hypercholesterolemia, iatrogenic (eg ERCP)
What are the chronic sequellae of pancreatitis?
Pancreatic pseudocyst
Splenic vein or portal vein thrombosis
Hemorrhagic pancreatitis
What are the PQRST symptoms of pancreatitis?
Epigastric pain
P: better leaning forward, worse lying down
Q: sharp (though can be dull)
R: radiates straight through to back (not around like chole issues)
S: severe
T: Acute, constant
What history is important to elicit in suspected pancreatitis?
EtOH Gallstones, biliary disease Hypercholesterolemia Recent procedures like ERCP Medications (eg thiazides can be linked)
How will a patient with pancreatitis appear on exam? (General appearance)
Ill; may be obtunded or diaphoretic
What vital sign abnormalities will be found in pancreatitis?
Tachycardia, fever, tachypnea
Hypotension (or orthostatic)
What will the HEENT and cardiac exams show in pancreatitis?
HEENT: dry mucous membranes, Sx of dehydration, scleral icterus
Chest: Normal (can have atelectasis from shallow breathing)
What will be found on abdo exam in pancreatitis?
- Soft, non-distended
- Moderate to severe tenderness in epigastrium or upper abdo
- Decreased bowel sounds
- Often, involuntary guarding
What other finding may be found on abdo exam in pancreatitis?
- if pseudocyst: may have palpable mass
- if hemorrhagic: Grey-Turner’s sign (R flank hematoma) or Cullen’s sign (periumbilical hematoma)
What is the hallmark of pancreatitis?
Severe dehydration and intravascular depletion
What is SIRS?
Systemic Inflammatory Response Syndrome: two or more of: - fever or hypothermia - tachycardia - tachypnea - change in blood leukocyte count
What lab finding is most sensitive and specific for pancreatitis?
Lipase: often elevated into the thousands
What imaging is ordered for suspected pancreatitis?
Abdo CT with Contrast is diagnostic (sensitive and specific). Can also Dx complications like pseudocyst, hemorrhagic pancreatitis
Consider AXR and CXR to r/o other causes
How is pancreatitis prognosis assessed?
CT scoring system (Balthazar score) based on degree of necrosis, inflammation, and the presence of fluid collections
How is pancreatitis treated acutely?
Fluid resuscitation with crystalloid and colloid Monitor electrolytes Pain control NPO Consider early nutritional support
What are some acute complications of pancreatitis?
Respiratory failure Hemodynamic instability/shock ARDS DIC Sepsis GI Bleed Progression to infected pancreatic necrosis
How is infected pancreatic necrosis diagnosed and treated? What is the mortality?
Dx: percutaneous aspiration
Tx: aggressive operative debridement
High mortality.
What procedures are done for pancreatitis?
Depends on presentation.
- pancreatic necrosectomy
- cholecystectomy
- drainage of cysts via cyst gastrotomy (IR, endoscopy, laparoscopic, open)
- splenectomy if splenic vein thrombosis
How long should a patient with pancreatitis be kept NPO?
Until pain-free.
Consider NGT if vomiting.
What are immediate post-op concerns with pancreatitis?
Bleeding
Ileus, return of bowel function
What are short-term post-op concerns with pancreatitis?
Surgical site infection
Anastomotic leak
Intra-abdominal abscess
Pancreatic leak
What are the signs of post-procedure intra-abdominal abscess?
Poor appetite
Low-grade fever
What are diverticula? Where are they found?
Small mucosal herniations in the colon.
Often at perforating vasa recta, ie weak points in colon wall.
Usually L colon (R in Asian pop)
Name three risk factors for developing diverticulitis
- Diverticula
- Increasing age
- Western population
Also possibly low fibre diet, constipation, obesity
What is tenesmus?
Continual or recurrent feeling of needing to evacuate bowels (even after having done so)
What are the clinical features of diverticulitis? (Name 2 presenting symptoms, + other SSx)
Main:
Steady, deep discomfort in LLQ
Change in bowel habits
Additional: Urinary symptoms Tenesmus GI Bleed Paralytic ileus SBO (Small bowel obstruction)
What physical findings are commonly present in diverticulitis?
- Low-grade fever
- Localized tenderness
- Left-sided pain on rectal exam
- Occult blood
- Rebound and guarding
- Peritoneal signs (suggest perforation or abscess rupture)
What investigation best confirms a diagnosis of diverticulitis?
CT scan (IV and oral contrast) Findings: - Pericolic fat stranding - Diverticula - Thickened bowel wall - Peridiverticular abscess
What lab finding is present in about 1/3 of patients with diverticulitis?
Leukocytosis (present in only 36% of patients)
What is the medical management of diverticulitis?
- Fluids
- Correct electrolyte abnormalities
- NPO
- Abx: For outpatients (non-toxic). Liquid diet x 48 hours, cipro and flagyl
What is the surgical management of diverticulitis?
Elective (uncomplicated): primary anastomosis
Emergency (complicated):
- Primary anastomosis with a proximal diversion, or
- Hartmann’s (resection with anorectal closure + end colostomy)
Is it necessary to resect all diverticulae?
No
Why might there be urinary symptoms in diverticulitis?
Spread of inflammation to nearby bladder
What is complicated diverticulitis?
Complicated diverticulitis includes perforation, abscess, obstruction, or fistula
What is the pathophysiology of appendicitis?
Obstruction of the lumen of the appendix
Continued secretion → impaired venous return & edema → arterial compromise, ischemia → gangrene → perforation
What is a phlegmon?
Mass of inflammatory tissue (e.g. can have a phlegmon next to an inflamed appendix)
What systems should be reviewed in suspected appendicitis?
GI, GU, Gyne, Resp, MSK, Trauma
What is the classic presentation of appendicitis, and approx what % of pt present this way?
1/2 to 2/3 present classically
- Periumbilical pain
- Anorexia, nausea, vomiting
- Pain localizes to RLQ
What % of appendices are retrocecal? in RUQ?
26% are retrocecal
4% are in RUQ
Where does a retrocecal appendicitis cause pain?
R flank
What symptoms does a suprapubic appendicitis cause?
Suprapubic pain
Dysuria
Where might men have pain from appendicitis?
Testicles
What signs are present on the physical exam in appendicitis?
Depends on duration of Sx
- RLQ tenderness (or ROsving sign: LLQ)
- Rebound tenderness, voluntary guarding, rigidity, tenderness on rectal exam
- Psoas or Obdurator sign
- Fever is a late finding (indicates rupture)
What labs aid in the diagnosis of appendicitis?
WBC usually mildly elevated (eg 12 x10^9/L; normal is 4-10 x10^9/L)
CBC is not sensitive or specific