genomic sequencing Flashcards

1
Q

genome

A

hereditary info encoded in DNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

genomic sequencing

A

process where exact sequence of nucleotide bases along gene or entire genome is determined

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

bioinformatics

A

comparison of gene sequences from diff organisms using comp and statistical analysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

highly conserved genes

A

very similar genome sequences to DNA sequences which are positively selected overtime

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

the more closely related the groups are…

A

the greater number of conserved DNA sequences they have in common in the genome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

phylogenetics

A

study of evolutionary history and relationships
- compares data from DNA sequences of diff species to determine how diff they are

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

why is sequence data used

A

to show evolutionary relatedness of genes between organisms among group of organisms
- to determine main sequence of events in evolution (along w fossil fuels)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

molecular clock

A

show when species diverged during evolution
- assume constant mutation rate and show differences in DNA or AA sequences

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what do the differences in sequence data is species indicate

A

the time of divergence from a common ancestor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

pharmacogenetics

A

use of genome info to advise and assist choice of drugs
- highly imp for improving drug therapy and prescribing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

an individuals genome sequence used to…

A

select most effective drug and dosage to treat their disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly