Genomic based population sacreening

Question 1

WILSON AND JUNGNER CRITERIA (Principles and practice of screening for disease.)

Answer 1

1. The condition is important health problem.
2. There is treatment and there are facilities for confirming the diagnosis and doing the treatment
3. There should be a recognizable latent or early symptomatic stage -> The natural history of the condition, including development from latent to declared disease, should be adequately understood.
4. The test should be acceptable to the population.
5. There should be an agreed policy on whom to treat as patients.
6. The cost of case-finding (including diagnosis and treatment of patients diagnosed) should be economically balanced in relation to possible expenditure on medical care as a whole.
7. Case-finding should be a continuing process and not a “once and for all” project (?)