genome projects Flashcards
1
Q
what is a genome?
A
the complete set of genetic information in the cells of an organism
2
Q
what is genome sequencing?
A
- identifying the dna base sequence of an individual
- allows us to determine the amino acid sequence of the polypeptides coded for by that DNA
3
Q
what is a proteome?
A
the complete set of proteins that can be produced by a cell
4
Q
give an application of sequencing the proteome in simple organisms?
A
identifying potential antigens for potential use in vaccine production
5
Q
give some applications of genome sequencing?
A
- comparing genomes between species to determine evolutionary relationships
- genetic matching
- personalised medicine
- synthetic biology
6
Q
How have sequencing methods changed over time?
A
- used to be a manual process, however now it has become automated
- a reaction mixture is created and after the process is complete, a machine reads the base sequence
7
Q
can we directly translate the genome into the proteome?
A
(simple organisms) YES
complex organisms - harder due to the presence of non-coding DNA and regularotry genes
