Genome Editing Flashcards

1
Q

How is genetic technology regulated?

A

Legislation
Normative documents
Policies
Regulations

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2
Q

What is human germ-line editing?

A

Manipulating the genes of reproductive cells.

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3
Q

What is human embryonic stem cell research?

A

The study of potential applications of pluripotent cells.

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4
Q

What is human reproductive cloning?

A

The cloning of reproductive cells

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5
Q

What is human somatic gene therapy?

A

The use of DNA modification to treat diseases.

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6
Q

What is human cloning research?

A

Research done on duplicates of human cells.

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7
Q

What is pre implantation genetic diagnosis?

A

The identification of genetic defects in embryos prior to implantation.

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8
Q

What is a prohibited embryo?

A

In Australian law, a prohibited embryo is an ámbito with an altered germ-line or an embryo that has been created solely for the purpose of research.

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9
Q

Describe three different approaches of regulations.

A

Restrictive
Intermediate
Permissive

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10
Q

Describe a restrictive law approach.

A

It outlaws all upstream practices and technology regardless of its purpose.

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11
Q

Who practices restrictive law?

A

Canada and Germany

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12
Q

Describe the Intermediate law approach.

A

It allows upstream applications and technology, yet forbids specific downstream applications.

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13
Q

Who has an intermediate law approach?

A

Japan and Israel

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14
Q

What is a permissive law approach?

A

Allows practices on a case by case basis.

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15
Q

Who has a permissive approach?

A

United States and Singapore

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16
Q

What is an eugenic trait?

A

Non-pathological genetic trait.

17
Q

What is the importance of preimplantation genetic diagnosis?

A

As proposed by Hinxton Group, PGD provides a self-regulatory approach and a potential model for defining research and clinical reproductive applications.

18
Q

What is the PGD model based on?

A

Gravity threshold
Prevention threshold
Transmission threshold

19
Q

In which countries human germline genetic modification is restrictive?

A

Canada, Germany, France, UK and Australia

20
Q

In which countries human germline genetic modification is legislative but intermediate?

A

United States

21
Q

In which countries human germline genetic modification is only regulatory and permissive?

A

Singapore and China

22
Q

Why is the definition of an embryo or germline an issue?

A

They both determine wether is a functional capability or a just a specific stage of development.

23
Q

Why is cautiousness a problem?

A

It may mean different things. Either being vigilant as informations and evidence is compiled or just setting tiers of restrictions and moratorias.

24
Q

Regarding prediagnostic embryo selection, which countries are regulatory and permissive?

A

Singapore, China, Japan, Israel

25
Q

Regarding prediagnostic embryo selection, which countries are restrictive?

A

Germany

26
Q

Regarding prediagnostic embryo selection, what’s the US take on?

A

Legislative but intermediate.

27
Q

Regarding reproductive cloning most countries are legislative and restrictive, except:

A

Singapore

28
Q

Human research cloning is restrictive in what countries?

A

Germany, Canada, Brasil France

29
Q

What’s United States’ take on human research cloning?

A

Regulatory but restrictive

30
Q

Human somatic cell therapy in the US is:

A

Intermediate and permissive.

31
Q

Human embryonic stem cell research is restrictive in which countries?

A

Canada and Germany