Genitourinary Flashcards
Bacteria associated with bacterial vaginosis?
Gardnerella vaginalis
mycoplasma hominis
prevotella species
RFs for bacterial vaginosis?
multiple sexual partners (not STI)
excessive vaginal cleaning
recent antibiotics
smoking
copper coil
Presentation of bacterial vaginosis?
fishy-smelling watery grey or white vaginal discharge
(not typical to have itching or pain -> alt diagnosis)
Investigations of bacterial vaginosis?
vaginal pH >4.5
vaginal swab (‘clue cells’ on microscopy)
Mx of bacterial vaginosis?
no treatment if asymptomatic (self-resolves)
metronidazole (oral or topical)
check for chlamydia or gonorrhoea where appropriate
Metronidazole interacts with?
alcohol
disulfiram-like reaction
Complications of bacterial vaginosis?
incr. risk of STIs
in pregnant women:
miscarriage
preterm delivery
PROM
chorioamnionitis
low birth weight
postpartum endometritis
What is bacterial vaginsosis?
overgrowth or bacteria in the vagina caused by a loss of friendly lactoballi
RFs for candidiasis?
incr. oestrogen
poorly controlled DM
immunosuppression
ABx
Presentation of thrush?
thick, white discharge that does not smell
vulval and vaginal itching, irritation or discomfort
Investigations for candidiasis?
not always necessary
vaginal pH <4.5
charcoal swab with microscopy
Mx of candidiasis?
antifungals
topical cream, pessary or oral
fluconazole oral
clotrimazole topically
pregnant women: topical only, fluconazole C/I
What is chlamydia trachomatis?
gram-negative bacteria
most common STI
cause of infertility
Presentation of chlamydia?
women asymptomatic
abnormal discharge
pelvic pain
abnormal vaginal bleeding
dyspareunia
dysuria
on exam:
pelvic or abdo tenderness
cervical excitation
cervicitis
purulent discharge
Diagnosis of chlamydia?
nucleic-acid amplification test
endocervical swab preferred