Genitourinary Flashcards
Urethra
cm? female and male
Urethra
* Females: 3-4 cm
* Males: 20 cm
functional capacity for bladder to empty the urine
functional capacity 400-500ml
- Oliguria:
- Anuria
- Normal
Oliguria: daily urine volume of less than 400 mL
* Anuria urine output of less than 100 mL/day
* Normal urine production is 0.5mL/kg/hr
GFR - glomerular filtration rate
GFR - glomerular filtration rate
* < 90 mL/min/1.73 m2 considered chronic kidney damage
< 60 mL/min/1.73 m2 considered irreversible kidney damag
Acute kidney injury Vs Chronic Kidney Failure
Acute kidney injury is a reversible syndrome that results in
decreased glomerular filtration rate and oliguria
- Chronic renal failure (ESRD) is a progressive, irreversible
deterioration of renal function that results in azotemia
Acute kidney injury cause
Prerenal
Intra-renal
Post-renal
Prerenal
*Hypoperfusion of kidney
* Hypovolemia
* Reduced cardiac output
* Vasodilation
Intrarenal
* Prolonged renal ischemia
* Nephrotoxic agents
* Infectious processes
Postrenal
* Urinary tract obstruction
Four Phases of Acute Kidney Injury
- Initiation
- Begins with the initial insult
Oliguria
* Increase in serum urea, creatinine, uric acid, organic acids, K+,
mag
Diuresis
* Increase in urine output
Recovery
* Renal function continues to improve
Urinalysis and urine culture:
Renal function tests:
Ultrasonography:
Urinalysis and urine culture
* Specific gravity, CYU, pH, protein,
glucose, ketones
Renal function tests
* GFR
Ultrasonography
* Bladder should be ful
What is the difference between Prerenal and
Intrarenal failure?
- Prerenal acute renal failure is characterized by diminished renal
blood flow (60 to 70 percent of cases). - In intrinsic acute renal failure, there is damage to the renal
parenchyma (25 to 40 percent of cases). - Postrenal acute renal failure occurs because of urinary tract
obstruction (5 to 10 percent of cases)
Acute Kidney Injury: clinical manifestations in oliguric phase
( Hint more like right-side heart failure symptoms)
- Peripheral edema, pulmonary edema, JVD, HTN
- Fatigue
- N/V
- SOB
- Confusion
- Seizures or coma
- Chest pain
Azotemia
abnormally high levels of nitroge
Initial diagnostic test for Acute kidney injury
Ultrasound
then CBC -
* Hemoglobin
Acute Kidney Injury: Tx medications for hyperkalemia especially
K+ is the most life-threatening in AKI
Hyperkalemia
- Sodium polystyrene sulfonate (PO, PR)
- Sorbitol
- IV insulin/D50
- IV bicarbonate
- Dialysis
Monitor nephrotoxic medications
example?
Contrast, biguanides, etc
Collaborative Problems and Complications
Hyperkalemia
* Pericarditis
* Pericardial effusion
* Pericardial tamponade (extra fluid builds up in the space around the
heart)
* Hypertension
* Anemia - lower production of erythropoietin production of RBCs
* Bone disease and metastatic calcifications (calcium salts in normal
tissue)