genito-urinary Flashcards

1
Q

what drug classes are used for genito-urinary (7)

A

alpha blockers
parasympathomimetics
antimuscarinics
potassium citrate
sodium citrate
vasodilators
phosphodiesterase type 5 inhibitors

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2
Q

what are drug examples of alpha-blockers (3)

A

alfuzosin
doxazosin
inodramin

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3
Q

what are alpha-blockers used for

A

urinary retention

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4
Q

what is the mechanism of action of alpha-blockers

A

prevent noradrenaline from tightening artery and vein muscles

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5
Q

what are the side effects of alpha-blockers (4)

A

drowsiness
hypotension
dizziness
headache

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6
Q

what are the cautions associated with alpha-blockers

A

avoid with history of postural hypotension

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7
Q

what is a drug example of a parasympathomimetic

A

bethanechol

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8
Q

what are parasympathomimetics used for

A

urinary retention

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9
Q

what is the mechanism of action of a parasympathomimetic

A

increase detrusor muscle contraction

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10
Q

what are the side effects of a parasympathomimetic (3)

A

N&V
abdominal pain
hypotension

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11
Q

what are drug examples of antimuscarinics (6)

A

oxybutynin
tolterodine
duloxetine
flavoxate
festoterodine
solifenacin

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12
Q

what are antimuscarinics used for

A

urinary incontinence

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13
Q

what is the mechanism of action of antimuscarinics (2)

A

reduce symptoms of urgency
increase bladder capacity

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14
Q

what are the side effects of antimuscarinics (5)

A

dry mouth
GI disturbances
taste disturbance
blurred vision
dry eyes

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15
Q

what is potassium citrate and sodium citrate used for

A

urological pain

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16
Q

what is the mechanism of action of potassium citrate and sodium citrate

A

alkalise the urine

17
Q

what are the cautions of potassium citrate and sodium citrate

A

caution with the elderly and in cardiac disease

18
Q

what is a drug example of a vasodialator

A

alprostadil

19
Q

what are vasodilators used for

A

erectile dysfunction

20
Q

what is the mechanism of action of vasodialators

A

dilate blood vessels

21
Q

what are drug examples of phosphodiesterase type 5 inhibitors (3)

A

sildenafil
tadalafil
vardenafil

22
Q

what are phosphodiesterase type 5 inhibitors used for

A

erectile dysfunction

23
Q

what is the mechanism of action of phosphodiesterase type 5 inhibitors

A

prevent the breakdown of of cyclic GMP so blood vessels dilate longer