Genetics of Complex Obesity Flashcards

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1
Q

What diseases are linked with obesity?

A
  • Type 2 Diabetes
  • Cardiovascular disease
  • Hypertension
  • Cancer
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2
Q

Genome Wide Association Studies (GWAS)

A
  • Large populations of people
  • Disease status and or trait information
  • Single nucleotide polymorphism (SNP) DNA genotypes at very high density - tend to be common variants
  • Statistical analysis tools
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3
Q

What is the FTO Locus

A

Region in 1st intron of FTO Gene on Chromosome 16, strongly associated with BMI and obesity in GWAS studies

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4
Q
A
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