Genetics - Linkage and recombination lectures 3-4 Flashcards

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1
Q

complete dominance

A

the phenotypes of the heterozygote and the dominant homozygote are identical

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2
Q

incomplete dominance

A

the phenotype of the f1 hybrids is somewhere between the two parental varieties

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3
Q

codominance

A

two dominant alleles affect the phenotype in separate, distinguishable ways

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4
Q

multiple alleles

A

most genes exist in more than one allelic form
for example, the gene for blood type.
This gene codes for the enzyme that adds either A or B carbohydrate to red blood cells.

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5
Q

pleiotropy

A

when one gene affects the phenotype in multiple ways

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6
Q

mendelian disorders

A

disorders caused by a single gene

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7
Q

DNA damage and repair

A

our dna is constantly being damaged and repaired

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8
Q

DNA ligase

A

an enzyme that repairs DNA

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9
Q

meiosis 1

A

homologous chromosomes separate

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10
Q

meiosis 2

A

sisters chromatids separate

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11
Q

tetrads

A

four part structure that forms during prophase of meiosis,

consisting of two homolgous chromosomes

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12
Q

crossing over/ recombination

A

in prophase one of meiosis, each pair of homologous chromosomes will slightly overlap and share and reshuffle dna at points called chiasma.

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13
Q

synaptonemal complex

A

during prophase 1 . the two homologous chromosomes join together via a protein scaffold. this joins the chromosomes along their length.

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14
Q

cohesion crosslinking

A

cohesion crosslinking occurs to hold the two chromosomes together and prevent them being pulles apart until anaphase.

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15
Q

independent assortement

A

when genes are located on different chromosomes hence they are inherited separately

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16
Q

complete linkage

A

when two genes are so close to each other on the chromosome that even crossing over will not separate them

17
Q

incomplete or partial linkage

A

when genes are far apart on a chromosome , hence crossing over may or may not affect them

18
Q

linkage

A

two genes are inherited together

19
Q

X inactivation

A

if the x chromosome of a mammalian female becomes inactive, the phenotype will be a mosaic of the two traits

20
Q

parental types

A

when the phenotype of the offspring is the same as the phenotype of the parent

21
Q

recombinants

A

when the phenotype of the offspring is a combination of the parents phenotype