Genetics

Question 1

What is the probability that a parent with phenylketonuria will have a child that carries the gene for the trait?

Answer 1

• Punnett square
• recessive
• mutated gene for the enzyme phenylalanine hydroxylase (PAH)

Question 2

What is the probability that a parent with Huntington’s disease will have a child who expresses the trait?

Answer 2

• Punnett square
• dominant
• production of mutant Huntintin protein

Question 3

Linkage Study: Purpose

Answer 3

to identify a genetic marker that is always inherited by those family members with the disease but not by those who do not have the disease

Question 4

Linkage Study: Kinds of Polymorphisms

Answer 4

• single nucleotide polymorphisms

Question 5

Are these linkage study polymorphisms, when linked with the disease or trait of interest, causally related to the expression of that trait (ie: are the identified linked genes the genes that cause the disease)?

Answer 5

• it might not be the SNP itself that causes the disease but a gene near that SNP