genetics Flashcards
Define Homologous Chromosomes
HC are similar in size, shape, gene locus, centromere position, and staining pattern,
have same genes determining certain trait at same loci,
but the gene may be of different alleles
define gene locus
Position of gene on chr,
where Alternative form of a gene, (having a different nucleotide sequence) occupies the same locus,
there are diff genes at diff locus
define gene
An ordered sequence of DNA nucleotide located at particular locus, on a particular
chr, that encodes for a specifical functional produc
Define alleles
Alternative form of a gene, having a different nucleotide sequence
define phenotype
Expressed trait of organism due to genotype & environmental influences
what makes a gene dominant?
An allele that expresses its phenotype regardless if its homozygous/heterozygous → gene
pdt of dominant allele masks effect of gene product expressed by recessive allele
how do you know a gene is recessive?
Allele that is only expressed in homozygous recessive organism
define codominance and give an example
When 2 different dominant alleles of the same genes are both equally expressed in heterozygote’s phenotype & influence the phenotype → Red/White flowers (both flowers exist) & AB blood group: IAIB
define incomplete dominance and give an example
When phenotype of heterozygous is an intermediate btwn phenotypes of both homozygous for either allele → Pink flowers (Red + White: CRCW= pink)
How do you carry out a test cross?
A cross with a homozygous recessive
Why do we do a test cross?
To determine whether the subject is homo dom/rec/heterozygous
Environment influences organisms. Give an example of the environment influencing the genetics of organism.
Temperature
Fur colour of Himalayan Rabbits:
Cooler body parts → black fur, Warmer body parts → white fur → reduce heat loss → survive better
Food
Diet of honeybees affect their Differentiation:
Larvae of honey bee fed with Royal Jelly → becomes Queen bees
Give the outcomes of the following MONOHYBRID crosses:
- Hh x Hh =
- Hh x hh = (test cross)
- hh x hh =
- HH x HH =
- Hh x Hh = 3:1
- Hh x hh = 1:1
- hh x hh = all recessive
- HH x HH = all dominant
An organism has 2 gene loci: A and B. Both A and B genes interact to determine the fur type of this organism. What kind of genetics interaction is happening here?
2 genes
1 trait
= epistasis
Gene interaction where a gene at 1 locus affects phenotypic expression of a gene at 2nd locus
If you cross a heterozygous for 2 gene loci, what outcome do you expect?
If the outcome is not you predicted, what kind of genetic interaction is happening?
e.g. AaBb x AaBb
= 9:3:3:1
If altered dihybrid ratio = Incomplete Linkage (most of the time)
IF THE RATIO BECOMES MONOHYBRID RATIO e..g 1:1 or 3:1 CONFIRMS COMPLETE* LINKAGE!