Genetic Material Flashcards

1
Q

Three Macromolecules that Comprise a Living Organism

A
  1. Carbohydrates
  2. Proteins
  3. Nucleic Acids
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2
Q

Deoxyribonucleic Acid (DNA) is first isolated by

A

Friedrich Miescher

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3
Q

Deoxyribonucleic Acid (DNA) is first isolated in

A

1869

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4
Q

He discovered microscopic substances from ____ among
surgical bandages.

A

pus

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5
Q

Radioactivity in liquid

A

Phages grown with radioactive sulfur (^35S)

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6
Q

Radioactivity in pellet

A

Phages grown with radioactive phosphorus (^32P)

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7
Q

Procedures of the phage experiment

A
  1. Mix radioactively labeled
  2. Agitate in a blender
  3. Centrifuge the mixture
  4. Measure the radioactivity
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8
Q

Introduced the currently accepted model of DNA, that of the double helix.

A

Francis Crick and James Watson

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9
Q

Introduced the currently accepted model of DNA, that of the double helix in the year

A

1953

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10
Q

Who also published a paper in Nature supporting the proposed
model, Crick and Watson were awarded the Nobel prize for
Medicine or Physiology.

A

Maurice Wilkins

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11
Q

The fundamental relationship of DNA, RNA and proteins

A

Central Dogma of Molecular Biology

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12
Q

DNA → RNA (mRNA) → Protein (Amino acids)

A

Central Dogma of Molecular Biology

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13
Q

DNA → RNA (mRNA)

A

Transcription

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14
Q

(mRNA) → Protein (Amino acids)

A

Translation

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15
Q

RNA (mRNA) → DNA

A

Reverse Transcription

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16
Q

The enzyme of Reverse Transcription

A

Reverse Transcriptase

17
Q

Synthesis of an RNA copy of a segment of DNA

A

Transcription

18
Q

The main repository of genetic information among all living
organisms and many viruses.

A

DNA

19
Q

Composed of two chains of biopolymer interlaced with one
another to form a double helix.

A

DNA

20
Q

Two strands are called _____________and are composed of smaller
units called _____________.

A

Polynucleotides; nucleotides

21
Q

Unzips DNA and attach to AT region

A

DNA Helicase

22
Q

A Y-shaped region where a cell’s DNA double helix is unwound and separated.

A

Replication Fork

23
Q

All nucleotide is made up of _____-containing bases

A

Nitrogen

24
Q

What are the components of DNA

A
  • Pentose sugar (5 carbons)
  • phosphate group
  • nucleobases
25
Q

Nucleobase linked to a sugar.

A

Nucleoside

26
Q

Difference of a Nucleosides and Nucleotides

A

Nucleoside:
- Base
- Sugar

Nucleotide:
- Base
- Sugar
- Phosphate

27
Q

Acts as the sugar backbone that connects all other DNA
components

A

Deoxyribose / D-2-deoxyribose

28
Q

Which is more flexible, RNA or DNA?

A

DNA, because it is double helix.

29
Q

What group are attached to RNA? DNA?

A

RNA: Hydroxyl (OH)
DNA: Hydrogen (H)

30
Q

Which is more prone to destruction, RNA or DNA?

A

RNA, because it is single stranded.

31
Q

An aldopentose, a monosaccharide with 5 carbon atoms and an
aldehyde as a functional group

A

2-deoxyribose

32
Q
A