genetic inheritance Flashcards
1
Q
Mendel’s 3 laws of inheritance
A
- segregation, 2 alleles per trait per individual, segregate during meiosis so gamete has 1 allele
- independent assortment, alleles for separate traits inherited independently
- dominance, recessive alleles are completely masked by dominant allele in heterozygous state
2
Q
exceptions to mendel’s 1st law, segregation
A
- clonal reproduction
- haplo-diploid organisms
- sex chromosomes
3
Q
exceptions to mendel’s 2nd law, independent assortment
A
- clonal reproduction
- chromosomal linkage, crossing over less likely to split up genes on same chromosome so more likely to be inherited together
4
Q
exceptions to mendel’s 3rd law, dominance
A
- incomplete dominance, phenotype of heterozygote is intermediate between the two homozygotes
- codominance, phenotype of heterozygote contains traits of both alleles
5
Q
epistasis
A
one gene modifies or controls the expression of another gene, can be dominant or recessive
6
Q
dominant epistasis
A
- dominant allele masks all alleles at other genes, recessive alleles have no effect
- e.g. white coat (and blue eyes and deafness) gene in cats
7
Q
recessive epistasis
A
- recessive allele masks other alleles if homozygous
- e.g. white coat genes in mice
8
Q
mendelian traits
A
trait controlled by one gene e.g. dry vs sticky earwax
9
Q
quantitative traits
A
- trait controlled by many genes e.g. height
- additive effect, as number of genes contributing to a trait increase, number of phenotypes increase and distribution of trait values approaches normal distribution