genetic inheritance Flashcards

1
Q

Mendel’s 3 laws of inheritance

A
  1. segregation, 2 alleles per trait per individual, segregate during meiosis so gamete has 1 allele
  2. independent assortment, alleles for separate traits inherited independently
  3. dominance, recessive alleles are completely masked by dominant allele in heterozygous state
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2
Q

exceptions to mendel’s 1st law, segregation

A
  • clonal reproduction
  • haplo-diploid organisms
  • sex chromosomes
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3
Q

exceptions to mendel’s 2nd law, independent assortment

A
  • clonal reproduction
  • chromosomal linkage, crossing over less likely to split up genes on same chromosome so more likely to be inherited together
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4
Q

exceptions to mendel’s 3rd law, dominance

A
  • incomplete dominance, phenotype of heterozygote is intermediate between the two homozygotes
  • codominance, phenotype of heterozygote contains traits of both alleles
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5
Q

epistasis

A

one gene modifies or controls the expression of another gene, can be dominant or recessive

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6
Q

dominant epistasis

A
  • dominant allele masks all alleles at other genes, recessive alleles have no effect
  • e.g. white coat (and blue eyes and deafness) gene in cats
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7
Q

recessive epistasis

A
  • recessive allele masks other alleles if homozygous
  • e.g. white coat genes in mice
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8
Q

mendelian traits

A

trait controlled by one gene e.g. dry vs sticky earwax

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9
Q

quantitative traits

A
  • trait controlled by many genes e.g. height
  • additive effect, as number of genes contributing to a trait increase, number of phenotypes increase and distribution of trait values approaches normal distribution
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